Control of Lymphoepithelial Interactions within Thymic Nurse Cells by Gamma-Interferon and Tumor Necrosis Factor Alpha. Possible Role in the Modulation of Intrathymic Education?
Defresne, Marie-Paule; Humblet, Chantal; Rongy, A. M.et al.
[en] The role of cytokines in the process of intrathymic differentiation is not yet clearly established. The results presented in this paper demonstrate that interferon-gamma and tumor necrosis factor-alpha regulate 'in vivo' and 'in vitro' the interactions between epithelial cells and thymocytes within thymic nurse cells. The mechanism of action of these cytokines and their possible physiologic role 'in vivo' are discussed.
Defresne, Marie-Paule ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie
Humblet, Chantal ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie
Rongy, A. M.
Boniver, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Language :
English
Title :
Control of Lymphoepithelial Interactions within Thymic Nurse Cells by Gamma-Interferon and Tumor Necrosis Factor Alpha. Possible Role in the Modulation of Intrathymic Education?
Publication date :
1989
Journal title :
Thymus
ISSN :
0165-6090
Publisher :
Kluwer Academic Publishers, Netherlands
Volume :
13
Issue :
3-4
Pages :
201-4
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
CAC - Centre anticancéreux près l'Université de Liège asbl FRSM - Fonds de la Recherche Scientifique Médicale
