L. LONDON T., MEGLYNN K. Liver cancer. In: SCHOTTENFELD D., FRAUMENI J. Cancer epidemiology and prevention, Oxford University Press, New-York, 1996.
MEGLYNN K., TSAO L., HSING A., DEVESA S., FRAUMENI J. International trends and patterns of primary liver cancer. Int. J. Cancer, 2001, 90: 290-296.
EL-SERAG H., MASON A. Rising incidence of hepatocellular carcinoma in the United States. N. Engl. J. Med., 1999, 340: 745-750.
EL-SERAG H., MASON A. Risk factors for the rising rates of primary liver cancer in the United States. Arch. Intern. Med., 2000, 180: 3227-3230.
CHANG M.H., CHEN C.J., LAI M.S., HSU H.M., WU T.C., KONG M.S., LIANG D.C., SHAU W.Y., CHEN D.S. Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group. N. Engl. J. Med., 1997, 336: 1855-9.
CHANG M.H., SHAU W.Y., CHEN C.J., WU T.C., KONG M.S., LIANG D.C., HSU H.M., CHEN H.L., HSU H.Y., CHEN D.S. The Taiwan Childhood Hepatoma Study Group. Hepatitis B vaccination and hepatocellular carcinoma rates in boys and girls. J. Ant. Med. Assoc., 2000, 284: 3040-2.
NIEDERAU C., HEINTGES T., LANGE S., GOLDMANN G., NIEDERAU C.M., MOHR L. et al. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N. Engl J. Med., 1996, 334: 1422-7.
LIN S.M., SHEEN I.S., CHIEN R.N., CHU C.M., LIAW Y.F. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology, 1999, 29: 971-5.
CAMMÀ C., GIUNTA M., ANDREONE P., CRAXI A. Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: an evidence-based approach. J. Hepatol., 2001, 34: 593-602.
KASAHARA A., HAYASHI N., MOCHIZUKI K., TAKAYANAGI M., YOSHIOKA K., KAKUMU S., IIJIMA A., URUSHIHARA A., KIYOSAWA K., OKUDA M., HINO K., OKITA K. Risk factors for hepatocellular carcinoma and its incidence after interferon treatment in patients with chronic hepatitis C. Osaka Liver Disease Study Group. Hepatology, 1998, 27: 1394-402.
CAMMA C., DI MARCO V., LO IACONO O., ALMASIO P., GIUNTA M., FUSCHI P., VACCARO A., FABIANO C., MAGRIN S., STEFANO R., BONURA C., PAGLIARO L., CRAXI A. Long-term course of interferon-treated chronic hepatitis C. J. Hepatol., 1998, 28: 531-7.
YOSHIDA H., SHIRATORI Y., MORIYAMA M., ARAKAWA Y., IDE T., SATA M., INOUE O., YANO M., TANAKA M., FUJIYAMA S., NISHIGUCHI S., KUROKI T., IMAZEKI F., YOKOSUKA O., KINOYAMA S., YAMADA G., OMATA M. Interferon therapy reduces the risk for hepatocellular carcinoma: national surveillance program of cirrhotic and noncirrhotic patients with chronic hepatitis C in Japan. IHIT Study Group. Inhibition of Hepatocarcinogenesis by Interferon Therapy. Ann. Intern. Med., 1999, 131: 174-81.
COLOMBO M. Screening for cancer in viral hepatitis. Clin. Liver Dis., 2001, 5: 109-121.
NGUYEN M., KEEFFE E. Screening for hepatocellular carcinoma. J. Clin. Gastroenterol., 2002, 35.
JOHNSON P., WILLIAMS R. Cirrhosis and the etiology of hepatocellular carcinoma. J. Hepatol., 1987, 4: 140-147.
CALVET X., BRUIX J., BRU C., GINES P., VILANA R., SOLE M., AYUSO M., BRUGUERA M., RODES J. Natural history of hepatocellular carcinoma in Spain. J. Hepatol., 1990, 10: 311-317.
THE CANCER OF THE LIVER ITALIAN PROGRAM (CLIP) INVESTIGATORS. A new prognostic system for hepatocellular carcinoma: A retrospective study of 435 patients. Hepatology, 1998, 28: 751-755.
OMATA M., TAKANO S. Occurrence of hepatocellular in chronic viral hepatitis. Cancer Chemother. Pharmacol., 1994, 33 (suppl): 5153-5154.
BRECHOT C., JAFFREDO F., LAGORCE D., GERKEN G., MEYER ZUN BÜSCHENFELDE K., PAPAKONSTONTINOU A., HADZIYANNIS S., ROMEO R., COLOMBO M., RODES J., BRUIX J., WILLIAMS R., NAOUMOV N. Impact of HBV, HCV and GBV-C/HGV on hepatocellular carcinoma in Europe: results of an european concerted action. J. Hepatol., 1998, 29: 173-183.
LIA Y.-F., TAI D.-I., CHU C.-M., LIN D.-Y., SHEEN I.-S., CHEN T.-J., PAO C.C. Early detection of hepatocellular carcinoma in patients with chronic type B hepatitis-A prospective study. Gastroenterology, 1986, 90: 263-267.
SHERMAN M., PELTEKIAN K., LEE C. Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: incidence and prevalence of hepatocellular carcinoma in a North America urban population. Hepatology, 1995, 22: 432-438.
IKEDA K., SAITOH S., SUZUKI Y., KOBAYASHI M., TSUBOTA A., KOIDA I., ARASE Y., FUKUDA M., CHAYAMA K., MURASHIMA N., KUMADA H. Disease progression and hepatocellular carcinogenese in patients with chronic viral hepatitis: a prospective observation of 2218 patients. J. Hepatol., 1998, 28: 930-938.
YANG H.-I., LU S.-N., LIAW Y.-F., YOU S.-L., SUN C.-A., WANG L.-Y., HSIAO C., CHEN P.-J., CHEN D.-S., CHEN C.-J. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N. Engl. J. Med., 2002, 347: 168-174.
TSUKUMA I., HIYANA T., TANAKA S., NAKAO H., YABUUCHI T., KITANURA T., NAKANISHI K., FUJIMOTO I., INOUE A., YANAZAKI H., KAWASHIMA T. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N. Engl. J. Med., 1993, 328: 1797-1801.
LOK A., LAI C.-L. Factors determining the development of hepatocellular carcinoma in hepatitis B surface antigen carriers. Cancer, 1988, 61: 1287-1291.
HENRION J., DE MAEGHT S., DELTENRE P., CHILAIN J.-M., MAISIN J.-M., SCHAPIRA M., HELLER F. Impact of hepatitis C virus infection on the aetiology of cirrhosis and hepatocarcinoma in the affiliated hospitals in Southern Belgium. Acta Gastroenterol. Belg., 2002, 65: 80-82.
HENRION J., LIBON E., DE MAEGHT S., DELTENRE P., SCHAPIRA M., GHILAIN J.-M., MAISIN J.-M., HELLER F. Dépistage du carcinome hépatocellulaire dans une cohorte de malades porteurs d'une cirrhose d'origine principalement alcoolique. Gastroenterol. Clin. Biol., 2003, 27: 534-539.
VAN GOSSUM A., DUBOIS P., LAURENT E., REDING P., BURETTE A., ADLER M., CREMER M. Les caractéristiques cliniques, biologiques et épidémioldgiques des hépatocarcinomes dans la région bruxelloise. Acta Gastroenterol. Belg., 1985, 48: 337-351.
CALVET X., BRUIX J., GINES P., BRU C., SOLE M., VILANA R., RODES J. Prognostic factors of hepatocellular carcinoma in the west: a multivariate analysis in 206 patients. Hepatology, 1990, 12: 753-763.
OKUDA K., OHTSUKI T., OBATA H., TOMINATSU M., OKAZAKI N., HASEGAWA H., NAKAJIMA Y., OHNISHI K. Natural history of hepatocellular carcinoma and prognosis in relation to treatment. Study of 850 patients. Cancer, 1985, 56: 912-928.
COLOMBO M. The natural history of hepatocellular carcinoma in western countries. Hepato-Gastroenterol., 1998, 45: 1221-1225.
TAKETA K. α-foetoprotein: reevaluation in hepatology. Hepatology, 1990, 12: 1420-1432.
SHERMAN M. α-foetoprotein: an obituary. J. Hepatol., 2001, 37: 603-605.
IKEDA K., SAITOH S., KOIDA I., ARASEY, TSUBOTA., CHAYAMA K., KUMADA H., KAWANISHI N. A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis. Hepatology. 1993, 18: 47-53.
OKA H., TAMORI A., KUROKI T., KOBAYASHI K., YAHAMOTO S. Prospective study of α-foetoprotein in cirrhotic patients monitored for development of hepatocellular carcinoma. Hepatology, 1994, 19: 61-66.
OKANO H., SHIRAKI K., INOUE H., ITO T., YAMANAKO T., DEGUCHI M., SUGIMOTO K., SAKAI T., OHMORI S., MURATA K., TAKASE K., NAKANO T. Comparison of screening methods for hepatocellular carcinoma in patients with cirrhosis. Anticancer Research, 2001, 21: 2979-2982.
ZOLI M., MAGALOTTI D., GUELLI C., MARCHESINI G., PISI E. Efficiency of a surveillance program for early detection of hepatocellular carcinoma. Cancer, 1996, 78: 977-985.
COLOMBO M., DE FRANCHIS R., DEL NINNO E., SANGIOVANNI A., DE FAZIO C., TOMMASINI M., DONATO F., PIVA A., DI CARLO V., DIOGUARDI N. Hepatocellular carcinoma in Italian patients with cirrhosis. N. Engl. J. Med., 1991, 325: 6.
PATERON D., GANNE N., TRINCHET J-C., AUROUSSEAU M-H., MAL F., MEICLER C., CODERC E., REBOULLET P., BEAUGRAND M. Prospective study of screening for hepatocellular carcinoma in Caucasian patients with cirrhosis. J. Hepatol., 1994, 20: 65-71.
COTTONE M., VIRDONE R., FUSCO G., ORLANDO A., TURRI M., CALTAGIRONE H., MARINGHINI A., SCIARRINO E., DEMMA I., NICOLI N., TINE F., SAMMARCO S., PAGLIARO L. Asymptomatic hepatocellular carcinoma in Child's A cirrhosis. A comparison of natural history and surgical treatment. Gastroenterology, 1989, 96: 1566-1571.
FAIVRE J., FORMAN D., ESTEVE J., OBRADOVIC M., SANT M. and the EUROCARE working group. - Survival of patients with primary liver cancer, pancreatic cancer and biliary tract cancer in Europe. Eur. J. Cancer, 1998, 34: 2184-2190.
EL-SERAG H., MASON A., KEY C. Trends in survival of patients with hepatocellular carcinoma between, 1977 and, 1996 in the United States. Hepatology, 2001, 33: 62-65.
BRUIX J., SHERMAN M., LLOVET J.M., BEAUGRAND M., LENCIONI R., BURROUGHS A.K., CHRISTENSEN E., PAGLIARO L., COLOMBO M., RODES J.; EASL PANEL OF EXPERTS ON HCC. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J. Hepatol., 2001, 35: 421-30.
HORIGOME H., NOMURA T., SASO K., ITOH M., JOH T., OHARA H.L. Limitations of imaging diagnosis for small hepatocellular carcinoma: comparison with histological findings. J. Gastroenterol. Hepatol., 1999, 14: 559-65.
LLOVET J.M., BEAUGRAND M. Hepatocellular carcinoma: present status and future prospects. J. Hepatol., 2003, 38 (Suppl 1): S136-S49.
DURAND F., REGIMBEAU J.M., BELGHITI J., SAUVANET A., VILGRAIN V., TERRIS B., MOUTARDIER V., FARGES O., VALLA D. Assessment of the benefits and risks of percutaneous biopsy before surgical resection of hepatocellular carcinoma. J. Hepatol., 2001, 35: 254-8.
KIM S.H., LIM H.K., LEE W.J., CHO J.M., JANG H.J. Needle-tract implantation in hepatocellular carcinoma: frequency and CT findings after biopsy with a 19,5-gauge automated biopsy gun. Abdom. Imaging, 2000, 25: 246-50.
LIU C., FRILLING A., DERESKEWITZ C., BROELSCH CE. Tumor seeding after fine needle aspiration biopsy and percutaneous radiofrequency thermal ablation of hepatocellular carcinoma. Dig. Surg., 2003, 20: 460-463.
MULIER S., MULIER P., NI Y., MIAO Y., DUPAS B., MARCHAL G., DE WEVER I., MICHEL L. Complications of radiofrequency coagulation of liver tumours. Br. J. Surg., 2002, 89: 1206-22.
TAKAMORI R., WONG L.L., DANG C., WONG L. Needle-tract implantation from hepatocellular cancer: is needle biopsy of the liver always necessary? Liver Transplantation, 2000, 6: 67-72.
PUGH R.N.H., MURRAY-LYON I.M., DAWSON J.L., PIETRONI M.C., WILLIAMS R. Transsection of the oesophagus for bleeding oesophageal varices. Br. J. Surg., 1973, 60: 646-9.
International Union against Cancer (UICC). TNM classification of malignant tumours. In: SOBIN L.H., WITTEKIND C.H. (eds). 5th ed. New York: Wiley-Liss, 1997: 74-7.
SORENSEN J.B., KLEE M., PALSHOF T., HANSEN H.H. Performance status assessment in cancer patients. An inter-observer validation study. Br. J. Cancer, 1993, 67: 773-5.
LLOVET J.M., BRU C., BRUIX J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin. Liver Dis., 1999, 19: 329-38.
BEFELER A.S., DI BISCEGLIE A.M. Hepatocellular carcinoma: diagnosis and treatment. Gastroenterology, 2002, 122: 1609-19.
RYDER S.D. Guidelines for diagnosis and treatment of hepatocellular carcinoma in adults. Gut, 2003, 52 (Suppl III): 1-8.
MAZZAFERRO V., REGALIA E., DOCI R., ANDREOLA S., PULVIRENTI A., BOZZETTI F., MONTALTO F., AMMANTUNA M., MORAHITO A., GENNARI L. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N. Eng. J. Med., 1996, 334(11): 693-699.
MC PEAKE J.R., O'GRADY J.G., ZAMAN S., PORTMANN B., WIGHT D.G., CALNE R.Y., WILLIAMS R. Liver transplantation for primary hepatocellular carcinoma: tumour size and number determine outcome. J. Hepatol., 1993, 18: 226-234.
LLOVET J.M., BRUIX J., FUSTER J., CASTELLS A., GARCIA-VALDECASAS J.C., GRANDE L., FRANCA A., BRU C., NAVASA M., AYUSO M.C., SOLE M., REAL M.I., VILANA R., RIMOLA A., VISA J., RODES J. Liver transplantation for small hepatocellular carcinoma: the tumour node metastasis classification does not have prognostic power. Hepatology, 1998, 27: 1572-1577.
RINGE B., PICHLMAYR R., WITTEKIND C., TUSCH G. Surgical treatment of hepatocellular carcinoma: experience with liver resection and transplantation in 19 198 patients. Word J. Surg., 1999, 15: 270-285.
BRUIX J., CASTELLS A., BOSCH J., FEU F., FUSTER J., GARCIA-PAGAN J.C., VISA J., BRU C., RODES J. Surgical resection of hepatocellular carcinoma in cirrhotic patients: prognostic value of preoperative portal pressure. Gastroenterology, 1996, 111: 1018-1022.
LLOVET J.M., FUSTER J., BRUIX J. Intention to treat analysis of surgical treatment for early hepatocellular carcinoma: resection versus transplantation. Hepatology, 1999, 30: 1434-1440.
FREEMAN R., WIESNER R., HARPER A., MC DIARMID S.V., LAKE J., EDWARDS E., MERION R., WOLFE R., TURCOTTE J., TEPERMAN L. UNOS/OPTN Liver disease severity score, UNOS/OPTN Liver and Intestine, and UNOS/OPTN pediatric transplantation committees. The new liver allocation system: moving toward evidence-based transplantation policy. Liver Transpl., 2002, 8: 851-858.
SARASIN F., MAJNO P., MAJNO P., LLOVET J.M., BRUIX J., MENTHA G., HADENGUE A. A liver donor liver transplantation for early hepatocellular carcinoma: a cost-effectiveness perspective. Hepatology, 2001, 33: 1073-1079.
BRUIX J., LLOVET J.M. Prognostic prediction and treatment strategy in hepatocellular carcinoma. Hepatology, 2002, 35: 519-524.
LIVRAGHI T., GIORGIO A., MARIN G., SALMI A., DE SIO I., BOLONDI L., POMPILI M., BRUNELLO F., LAZZZARONI S., TORZILLI G. Hepatocellular carcinoma and cirrhosis in 746 patients: long term results of percutaneous ethanol injection. Radiology, 1995, 197: 101-108.
BUSCARINI L., BUSCARINE E., DI STASI M., VALLISA D., QUARETTI P., ROCCA A. Percutaneous radiofrequency ablation of small hepatocellular carcinoma, long-term results. Eur. Radiol., 2001, 11: 914-921.
LENCIONE R.A., ALLGAIER H.P., CIONI D., OLSCHEWSKI M., DEIBERT P., CROCETTI L., LAUBENBERGER J., ZUBER I., BLUM H.E., BARTOLOZZI C. Small hepatocellular carcinoma in cirrhosis : randomised comparison of radio-frequency thermal ablation versus percutaneous ethanol injection. Radiology, 2003, 228: 235-240.
LLOVET J.M., BRUIX J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival Hepatology, 2003, 37: 429-42.
TRINCHET J.C., GANNE-CARRIE N., BEAUGRAND M. Review article: intra-arterial treatments in patients with hepatocellular carcinima. Aliment Pharmacol. Ther., 2003,17 (Suppl. 2): 111-118.
SHEU J., SUNG J., CHEN D., YANG P., LAI M., LEE C., HSU H., CHUANG C.N., YANG P.C., WANG T.H. Growth rates of asymptomatic hepatocellular carcinoma and its clinical implications. Gastroenterology, 1985, 89: 259-266.
LLOVET J., MAS X., APONTE J., FUSTER J., NAVASA M., CHRISTENSEN E., RODÉS J., BRUIX J. Cost effectiveness of adjuvant therapy for hepatocellular carcinoma during the waiting list for liver transplantation. Gut, 2002, 50: 123-128.
LLOVET J., VILANA R., BRU C., BIANCHI L., SALMERON J., BOIX L., GANAN S., SALA M., PAGES M., AYUSO C., SOLE M., RODES J., BRUIX J. The Barcelona Clinic Liver Cancer Group. Increased risk of tumor seeding after precutaneous radio frequency ablation for single hepatocellular carcinoma. Hepatology, 2001, 33: 1124-1129.
FONTANA R.J., HAMIDULLAH H., NGHIEM H., GREENSON J.K., HUSSAIN H., MARRERO J., RUDICH S., MC CLURE L.A., ARENAS J. Percutaneous radiofrequency thermal ablation of HCC: a safe and affective bridge to liver transplantation. Liver Transplantation, 2002, 8: 1165-1174.
LIVRAGHI T., SOLBIATI L., MELONI M.F., GAZELLE G.S., HALPERN E.F., GOLDBERG S.N. Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology, 2003, 226: 441-451.
RICHARD H., SILBERZWEIG J., MITTY H., LOU W., AHN J., COOPER J. Hepatic arterial complications in liver transplant recipients treated with pretransplantation chemoembolisation for hepatocellular carcinoma. Radiology, 2000, 214: 775-779.
MAJNO P., ADAM R., BISMUTH H., CASTAING D., ARICHE A., KRISSAT J., PERRINH., AZOULAY D. Influence of preoperative trans-arterial lipiodol chemoembolisation on resection and transplantation for hepatocellular carcinoma in patients with cirrhosis. Ann. Surg., 1997, 226: 688-703.
HARNOIS D., STEERS I., ANDREWS J., RUBIN J., PITOT H., BURGART L., WIESNER R., GORES G. Preoperative hepatic artery chemoembolisation followed by orthotopic liver transplantation for hepatocellular carcinoma. Liver Transpl. Surg. Liver Transpl. Surg., 1999, 5: 192-199.
OLDHAFER K., CHAVAN A., FRUHAUF N., FLEMMING P., SCHLITT H., KUBIN S., NASHAN B., WEIMANN A., RAAB R., MANNS M., GALANSKI M. Arterial chemoembolization before liver transplantation in patients with hepatocellular carcinoma: marked tumor necrosis but no survival benefit. J. Hepatol., 1998, 29: 953-959.
VENOOK A., FERRELL L., ROBERTS J., EMOND J., FRYE J., RING E., ASHER N.L., JAKE J.R. Liver transplantation for hepatocellular carcinoma: results with preoperative chemoembolization. Liver Transpl. Surg. Liver Transpl. Surg., 1995, 1: 242-248.