[en] Clinical proteomics is a technical approach studying the entire proteome
expressed by cells, tissues or organs. It describes the dynamics of cell
regulation by detecting molecular events related to diseases development.
Proteomic techniques focus mainly on identification of new biomarkers or new
therapeutic targets. It is a multidisciplinary approach using medical,
biological, bioanalytical and bioinformatics knowledges. A strong collaboration
between these fields allowed SELDI-TOF-MS proteomics studies to be performed at
the CHU and the University of Liege, in GIGA-Research facilities. The aim of
these studies was driven along three main axes of research related to the
identification of biomarkers specific to a studied pathology, to a common
biological pathway and, finally, to a treatment response.
