[en] Prader Willi syndrome can be viewed as a physiopathological model of obesity. Such patients deserve specific management, preferably in a multidisciplinary setting. The paper reports on 6 patients followed in the paediatric endocrine service at the University of Liege.
Disciplines :
Pediatrics Neurology
Author, co-author :
Salmon, C.
Gaillez, Stephanie ; Centre Hospitalier Universitaire de Liège - CHU > Génétique
Pieltain, Catherine ; Centre Hospitalier Universitaire de Liège - CHU > Néonatologie
Sacre, F.
Misson, Jean-Paul ; Université de Liège - ULiège > Département des sciences cliniques > Pédiatrie
Rocour-Brumioul, D.
Bourguignon, Jean-Pierre ; Université de Liège - ULiège > Département des sciences cliniques > Pédiatrie
Prader A, Labhart A, Willi H.- Ein Syndrome von Adipositas, Kleinwuchs, Kryptorchismus und Oligophrenie nach myotoniear-tigem Zustand im Neugeborenenalter. Schweiz Med Wochenschr, 1956, 86, 1260-1261.
Holm VA, Cassidy SB, Butler MG, et al.- Prader-Willi syndrome. Consensus diagnostic criteria. Pediatrics, 1993, 91, 398-402.
Bray GA, Dahms WT, Swerdloff RS, et al.- The Prader-Willi syndrome. A study of 40 patients and a review of the literature. Medecine, 1983, 62, 59-80.
Cummings DE, Clement K, Purnell JQ, et al.- Elevated plasma ghrelin levels in Prader-Willi syndrome. Nature medecine, 2002, 8, 643-644.
Delparigi A, Tschöp M, Heiman ML, et al.- High circulating ghrelin: a potential cause for hyperphagia and obesity in Prader-Willi syndrome. J Clin Endocrinol Metab, 2002, 87, 5461-5464.
Burman P, Ritzén EM, Lindgren AC.- Endocrine dysfunction in Prader-Willi syndrome: A review with special reference to GH. Endocrine Reviews, 2001, 22, 787-799.
L'Allemand D, Eiholzer U, Rousson V, et al.- Increased adrenal androgen levels in patients with Prader-Willi syndrome are associated with insulin, IGF-1, and leptin, but not with measures of obesity. Horm Res, 2002, 58, 215-222.
Dykens EM, Cassidy SB.- Prader-Willi syndrome. Genetic, behavioral, and treatment issues. Child Adolesc Psychiatr Clin North Am, 1996, 5, 913-927.