PLENA and FARINELLI: redundancy and regulatory interactions between two Antirrhinum MADS-box factors controlling flower development.

Davies, B.; Motte, Patrick; Keck, E.; Saedler, H.; Sommer, H.; Schwarz-Sommer, Z.

doi:10.1093/emboj/18.14.4023

Article (Scientific journals)

PLENA and FARINELLI: redundancy and regulatory interactions between two Antirrhinum MADS-box factors controlling flower development.

Davies, B.; Motte, Patrick; Keck, E. et al.

1999 • In EMBO Journal, 18 (14), p. 4023-34

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https://hdl.handle.net/2268/71673

DOI
10.1093/emboj/18.14.4023

PubMed
10406807

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Keywords :

Amino Acid Sequence; Arabidopsis/chemistry/genetics; Cloning, Molecular; DNA-Binding Proteins/chemistry/genetics/metabolism; Fertility; Gene Expression; Gene Expression Regulation, Developmental; Gene Expression Regulation, Plant; Genes, Homeobox/genetics; Genes, Plant/genetics/physiology; MADS Domain Proteins; Models, Biological; Molecular Sequence Data; Mutagenesis, Insertional; Mutation/genetics; Phenotype; Phylogeny; Plant Proteins/chemistry/genetics/metabolism; Plant Structures/genetics/growth & development/physiology; Plants, Genetically Modified; Plants, Toxic; RNA, Messenger/genetics/metabolism; Tobacco/genetics; Transcription Factors/chemistry/genetics/metabolism

Abstract :

[en] We report the discovery of an Antirrhinum MADS-box gene, FARINELLI (FAR), and the isolation of far mutants by a reverse genetic screen. Despite striking similarities between FAR and the class C MADS-box gene PLENA (PLE), the phenotypes of their respective mutants are dramatically different. Unlike ple mutants, which show homeotic conversion of reproductive organs to perianth organs and a loss of floral determinacy, far mutants have normal flowers which are partially male-sterile. Expression studies of PLE and FAR, in wild-type and mutant backgrounds, show complex interactions between the two genes. Double mutant analysis reveals an unexpected, redundant negative control over the B-function MADS-box genes. This feature of the two Antirrhinum C-function-like genes is markedly different from the control of the inner boundary of the B-function expression domain in Arabidopsis, and we propose and discuss a model to account for these differences. The difference in phenotypes of mutants in two highly related genes illustrates the importance of the position within the regulatory network in determining gene function.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Davies, B.

Motte, Patrick ; Université de Liège - ULiège > Département des sciences de la vie > Génomique fonctionnelle et imagerie moléculaire végétale

Keck, E.

Saedler, H.

Sommer, H.

Schwarz-Sommer, Z.

Language :

English

Title :

PLENA and FARINELLI: redundancy and regulatory interactions between two Antirrhinum MADS-box factors controlling flower development.

Publication date :

1999

Journal title :

EMBO Journal

ISSN :

0261-4189

eISSN :

1460-2075

Publisher :

Oxford University Press, Oxford, United Kingdom

Volume :

Issue :

Pages :

4023-34

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 11 September 2010

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221

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