Hypertension artérielle et antagonistes du récepteur de l'angiotensine II

Krzesinski, Jean-Marie; Turatzinse, L.; Rorive, Georges

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Hypertension artérielle et antagonistes du récepteur de l'angiotensine II

Krzesinski, Jean-Marie; Turatzinse, L.; Rorive, Georges

1996 • In Médecine et Hygiène, 2127, p. 1480-1486

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Keywords :

antagonistes des récepteurs del'angiotensine II; hypertension artérielle; angiotensine II; récepteurs de l'angiotensine II

Abstract :

[fr] Dans l'hypertension artérielle et la décompensation cardiaque, les inhibiteurs de l'enzyme de conversion constituent un outil thérapeutique important mais, parfois, au prix de certains effets secondaires (par exemple, la toux). De nouvelles perspectives de contrôle du système rénine angiotensine-aldostérone se profilent à l'horizon avec l'avènement des antagonistes des récepteurs de l'angiotensine Il. Le losartan est lepremier agent de cette famille, de nature non peptidique et actif par voie orale. Sa longue durée d'action permet une seule administration par jour. Cet agent bloque tous les effets connus de l'angiotensine II par une action au niveau des récepteurs appelés AT1. Au vu des premiers résultats publiés, il constitue un concurrent des inhibiteurs de l'enzyme de conversion dans l'hypertension et la décompensation cardiaque.

Disciplines :

Urology & nephrology

Author, co-author :

Krzesinski, Jean-Marie ; Université de Liège - ULiège > Néphrologie

Turatzinse, L.

Rorive, Georges ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques

Language :

French

Title :

Hypertension artérielle et antagonistes du récepteur de l'angiotensine II

Publication date :

1996

Journal title :

Médecine et Hygiène

ISSN :

0025-6749

Publisher :

Editions Médecine et Hygiène

Volume :

2127

Pages :

1480-1486

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 12 August 2010

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