Relationship between maternal concentrations of caprine pregnancy-associated glycoprotein in Alpine goats and the number of fetuses using a homologous radioimmunoassay
Batalha, E. S.; Sulon, Joseph; Figueiredo, J. R.et al.
2001 • In Small Ruminant Research, 42 (2), p. 105-109
[en] The relationship between maternal caprine pregnancy-associated glycoprotein (cPAG) concentrations and fetal number was investigated in 21 nulliparous and 17 multiparous goats. Using a homologous radioimmunoassay (hm-RIA) cPAG was detected in plasma of pregnant goats from the 21st day of pregnancy. Statistical differences between goats bearing single and multiple fetuses were observed after 63 days to the end of pregnancy, except on day 133. After 126 days (3rd week pre-partum) cPAG levels began to decrease slowly in both the groups. The hm-RIA was an efficient method to describe the relationship between maternal PAO concentrations and number of fetuses in goats. (C) 2001 Published by Elsevier Science B.V.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Batalha, E. S.
Sulon, Joseph ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Figueiredo, J. R.
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Martins, G. A.
Silva, L. D. M.
Language :
English
Title :
Relationship between maternal concentrations of caprine pregnancy-associated glycoprotein in Alpine goats and the number of fetuses using a homologous radioimmunoassay
Benitez Ortiz W. Diagnostic de pregnancy et étude de la mortalité embryonnaire chez les ruminants par dosage de la pregnancy associated glycoprotein (PAG) (diagnosis of pregnancy and embryonic mortality in ruminants by radioimmunoassay of pregnancy-associated glycoprotein), Ph.D. Thesis, Institut de Medicine Tropicale Prince Léopold, Antwerp, Belgium; 1992.
Folch J., Benitez Ortiz W., Alabart J.L., Beckers J.F. (1993) Plasma concentration of pregnancy associated glycoprotein (PAG) in Blanca Celtibérica goats and its application for pregnancy diagnosis. ITEA, V Jornada Sobre Producción Animal, Volumen Extra 2(12):364-366.
Garbayo J.M., Remy B., Alabart J.L., Folch J., Wattiez R., Falmagne P., Beckers J.F. (1998) Isolation and partial characterization of a pregnancy-associated glycoprotein family from the goat placenta. Biol. Reprod. 58(1):109-115.
Hayden T.J., Thomas C.R., Forsyth I.A. (1979) Effect of number of young born (litter size) on milk yield of goats: Role for placental lactogen. J. Dairy Sci. 62:53-57.
Mialon M.M., Camous S., Renand G., Martal J., Ménissier F. (1993) Peripheral concentrations of a 60-kDa pregnancy serum protein during pregnancy and after calving and in relationship to embryonic mortality in cattle. Reprod. Nutr. Dev. 33:269-282.
Osborn D.A., Beckers J.F., Sulon J., Gassett J.W., Muller L.I., Murphy B.P., Miller K.V., Marchinton R.L. (1996) Use of glycoprotein assay for pregnancy diagnosis in white-tailed deer. J. Wildlife Manage 60(2):388-393.
Ranilla M.J., Sulon J., Carro M.D., Mantecón A.R., Beckers J.F. (1994) Plasmatic profiles of pregnancy-associated glycoprotein and progesterone levels during pregnancy in Churra and Merino sheep. Theriogenology 42:537-542.
Roberts R.M., Xie S., Nagel R.J., Low G.B., Green J., Beckers J.F. (1995) Glycoproteins of the aspartyl proteinase gene family secreted by the developing placenta. Aspartic Proteinase: Structure, Function, Biology and Biomedical Implications , Takahashi, K. (Ed.). Plenum Press, New York; 231-240.
User's Guide: Statistics, Version 6.11, SAS Institute Inc., Cary, NC; 1996.
Skinner J.G., Gray D., Gebbie F.E., Beckers J.F., Sulon J. (1996) Field evaluation of pregnancy diagnosis using bovine pregnancy-associated glycoprotein (bPAG). Cattle Prac. BCVA 4(3):281-284.
Vasques M.I., Horta A.E.M., Marques C.C., Sasser R.G., Humblot P. (1995) Levels of bPSP-B throughout single and twin pregnancies after AI or transfer of IVM/IVF cattle embryos. Anim. Reprod. Sci. 38:279-289.
Wooding F.B.P. (1992) Current topic: The synepitheliochorial placenta of ruminants: Binucleate cell fusion and hormone production. Placenta 13:101-113.
Wooding F.B.P., Morgan G., Monaghan S., Hamon M., Heap R.B. (1996) Functional specialization in the ruminant placenta: Evidence for two populations of foetal binucleate cells of different selective synthetic capacity. Placenta 17:75-86.
Xie S., Low B.G., Nagel R.J., Kramer K.K., Anthony R.V., Zoli A.P., Beckers J.F., Roberts R.M. (1991) Identification of the major pregnancy-specific antigens of cattle and sheep as inactive members of the Aspartic proteinase family. Proc. Natl. Acad. Sci. U.S.A. 88:10247-10251.
Zoli A.P., Beckers J.F., Woulters-Ballman P., Closset J., Falmagne P., Ectors F. (1991) Purification and characterization of a bovine pregnancy associated glycoprotein. Biol. Reprod. 45:1-10.
Zoli A.P., Guilbault L.A., Delahaut P., Benitez-Ortiz W., Beckers J.F. (1992) Radioimmunoassay of a bovine pregnancy glycoprotein in serum: Its application for pregnancy diagnosis. Biol. Reprod. 46:83-92.
Zoli A.P., Beckers J.F., Benitez Ortiz W., Ectors F. (1993) Isolement, purification et caractérisation d'une glycoprotéine placentaire bovine: Mise au point d'une dosage radioimmunologique sensible et spécifique. Actualité Scientifique, Maîtrise de la reproduction et amélioration génétique des ruminants. Edition Aupelf 235-247.
