Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element

Anti-Bacterial Agents/pharmacology; Cameroon; *DNA Transposable Elements; Drug Resistance, Multiple, Bacterial/*genetics; Escherichia coli/drug effects/*enzymology/genetics; Humans; Klebsiella pneumoniae/drug effects/*enzymology/genetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; beta-Lactamases/*biosynthesis/genetics

Abstract :

[en] CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli emerged recently in Cameroon. CTX-M-15 was encoded by two different multiresistance plasmids, of which one carried an ISEcp1-bla(CTX-M-15) element flanked by a 5-bp target site duplication and inserted within a Tn2-derived sequence. A truncated form of this element in the second plasmid was identified.

Disciplines :

Microbiology

Author, co-author :

Gangoue Pieboji, Joseph ; Institut de Recherches médicales et d'étude des plantes médicinales -IMPM-cameroun

Miriagou, V.

Vourli, S.

Tzelepi, E.

Ngassam, P.

Tzouvelekis, L. S.

Language :

English

Title :

Emergence of CTX-M-15-producing enterobacteria in Cameroon and characterization of a blaCTX-M-15-carrying element

Publication date :

2005

Journal title :

Antimicrobial Agents and Chemotherapy

ISSN :

0066-4804

eISSN :

1098-6596

Publisher :

American Society for Microbiology (ASM), Washington, United States - District of Columbia

Volume :

Issue :

Pages :

441-3

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

2004/12/24

Available on ORBi :

since 22 June 2010

Statistics

Number of views

68 (0 by ULiège)

Number of downloads

166 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Arlet, G., Brami, G., Decre, D., Flippo, A., Gaillot, O., Lagrange, P.H., Philippon, A., Molecular characterisation by PCR-restriction fragment length polymorphism of TEM β-lactamases (1995) FEMS Microbiol. Lett., 134, pp. 203-208
Baraniak, A., Fiett, J., Hryniewicz, W., Nordmann, P., Gniadkowski, M., Ceftazidime-hydrolysing CTX-M-15 extended-spectrum-β-lactamase (ESBL) in Poland (2002) J. Antimicrob. Chemother., 50, pp. 393-396
Bonnet, R., Growing group of extended-spectrum β-lactamases: The CTX-M enzymes (2004) Antimicrob. Agents Chemother., 48, pp. 1-14
Decousser, J.W., Poirel, L., Nordmann, P., Characterization of a chromosomally encoded extended-spectrum class A β-lactamase from Kluyvera cryocrescens (2001) Antimicrob. Agents Chemother., 45, pp. 3595-3598
Edelstein, M., Pimkin, M., Palagin, I., Edelstein, I., Stratchounski, L., Prevalence and molecular epidemiology of CTX-M extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Russian hospitals (2003) Antimicrob. Agents Chemother., 47, pp. 3724-3732
Karim, A., Poirel, L., Nagarajan, S., Nordmann, P., Plasmid-mediated extended-spectrum-β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1 (2001) FEMS Microbiol. Lett., 201, pp. 237-241
Lartigue, M.F., Poirel, L., Heritier, C., Tolun, V., Nordmann, P., First description of CTX-M-15-producing Klebsiella pneumoniae in Turkey (2003) J. Antimicrob. Chemother., 52, pp. 315-316
Lartigue, M.F., Poirel, L., Nordmann, P., Diversity of genetic environment of blaCTX-M genes (2004) FEMS Microbiol. Lett., 234, pp. 201-207
Mahillon, J., Chandler, M., Insertion sequences (1998) Microbiol. Mol. Biol. Rev., 62, pp. 725-774
Mushtaq, S., Woodford, N., Potz, N., Livermore, D.M., Detection of CTX-M-15 extended-spectrum-β-lactamase in the United Kingdom (2003) J. Antimicrob. Chemother., 52, pp. 528-529
Neuwirth, C., Siebor, E., Pruneaux, M., Zarnayova, M., Simonin, C., Kisterman, J.P., Labia, R., First isolation of CTX-M15-producing Escherichia coli from two French patients (2003) J. Antimicrob. Chemother., 51, pp. 471-473
Pagani, L., Dell'Amico, E., Migliavacca, R., D'Andrea, M.M., Giacobone, E., Amicosante, G., Romero, E., Rossolini, G.M., Multiple CTX-M-type extended-spectrum-β-lactamases in nosocomial isolates of Enterobacteriaceae from a hospital in northern Italy (2003) J. Clin. Microbiol., 41, pp. 4264-4269
Poirel, L., Decousser, J.-W., Nordmann, P., Insertion sequence ISEcp1B is involved in expression and mobilization of a blaCTX-M, β-lactamase gene (2003) Antimicrob. Agents Chemother., 47, pp. 2938-2945
Poirel, L., Gniadkowski, M., Nordmann, P., Biochemical analysis of the ceftazidime-hydrolysing extended-spectrum- β-lactamase CTX-M-15 and of its structurally related β-lactamase CTX-M-3 (2002) J. Antimicrob. Chemother., 50, pp. 1031-1034
Siu, L.K., Lo, J.Y.C., Yuen, K.Y., Chau, P.Y., Ng, M.H., Ho, P.L., β-lactamases in Shigella flexneri isolates from Hong Kong and Shanghai and a novel OXA-1-like β-lactamase, OXA-30 (2000) Antimicrob. Agents Chemother., 44, pp. 2034-2038
Tzouvelekis, L.S., Tzelepi, E., Tassios, P.T., Legakis, N.J., CTXM-type beta-lactamases: An emerging group of extended-spectrum enzymes (2000) Int. J. Antimicrob. Agents, 14, pp. 137-142
Yu, W.-L., Cheng, K.-C., Wu, L.-T., Pfaller, M.A., Winokur, P.L., Jones, R.N., Emergence of two Klebsiella pneumoniae isolates harboring plasmid-mediated CTX-M-15 β-lactamase in Taiwan (2004) Antimicrob. Agents Chemother., 48, pp. 362-363