Article (Scientific journals)
Impact of erythropoietic activity on red cell parameters in chronic renal failure patients.
Bovy, Christophe; Krzesinski, Jean-Marie; Gothot, André et al.
2004In Haematologica, 89 (6), p. 748-9
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Keywords :
Erythrocyte Indices; Erythrocytes/pathology; Erythropoiesis; Humans; Kidney Failure, Chronic/blood
Abstract :
[en] We measured red cell parameters during recombinant human erythropoietin (rHuEPO) therapy associated with appropriate iron supplementation in chronic hemodialysis patients. Increased erythropoietic activity led to a bias in red cell parameter determination. The percentage of hypochromic red blood cells, usually used as the most effective predictor of response to iron supplementation, increased following the appearance of a younger red cell population since the same Hb content in these younger, larger cells gives a lower Hb concentration.
Disciplines :
Hematology
Author, co-author :
Bovy, Christophe ;  Centre Hospitalier Universitaire de Liège - CHU > Néphrologie
Krzesinski, Jean-Marie ;  Centre Hospitalier Universitaire de Liège - CHU > Néphrologie
Gothot, André ;  Centre Hospitalier Universitaire de Liège - CHU > Hématologie biologique et immuno hématologie
Beguin, Yves  ;  Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique
Language :
English
Title :
Impact of erythropoietic activity on red cell parameters in chronic renal failure patients.
Publication date :
2004
Journal title :
Haematologica
ISSN :
0390-6078
eISSN :
1592-8721
Publisher :
Ferrata Storti Foundation, Pavia, Italy
Volume :
89
Issue :
6
Pages :
748-9
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 16 February 2009

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