Diagnostic differentiel et traitement medical dans la maladie de Cushing.

ACTH Syndrome, Ectopic/complications; Adenoma/complications/diagnosis/secretion/surgery; Adrenal Cortex Neoplasms/complications/surgery; Adrenocortical Hyperfunction/complications/drug therapy; Adrenocorticotropic Hormone/blood/secretion; Adult; Algorithms; Carcinoid Tumor/secretion; Child; Corticotropin-Releasing Hormone/diagnostic use; Cushing Syndrome/classification/diagnosis/drug therapy/etiology; Dexamethasone/diagnostic use; Diagnosis, Differential; Diagnostic Imaging; Dopamine Agonists/therapeutic use; Female; Humans; Hypothalamo-Hypophyseal System/drug effects/physiopathology; Magnetic Resonance Imaging; Male; Petrosal Sinus Sampling; Pituitary Neoplasms/complications/diagnosis/secretion/surgery; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System/drug effects/physiopathology; Pregnancy; Pregnancy Complications, Neoplastic; Vasopressins/diagnostic use; Exploration radioisotopique; Radiodiagnostic; Imagerie médicale; Hypercorticisme; Corticosurrénale pathologie; Surrénale pathologie; Tumeur bénigne; Endocrinopathie; Hypophyse pathologie; Homme; Traitement; Diagnostic; Analyse biochimique; Positon; Emission; Tomoscintigraphie; Tomodensitométrie; Imagerie RMN; Cushing syndrome; Hypophyse; Adénome

Abstract :

[en] Cushing's disease remains a difficult diagnosis in spite of new technical procedures such as pituitary MRI, selective bilateral petrosal or cavernous sampling, (111)In pentreotide scan and 18 Flurodeoxyglucose pituitary PET scan. In this article, we review biological diagnostic procedures of Cushing's disease and corticotroph adenomas. According to our experience and the literature, we summarize the approach in medical treatment of Cushing's disease.
[fr] Le diagnostic de la maladie de Cushing reste difficile en dépit des nombreuses avancées techniques telles que l'IRM hypophysaire, le cathétérisme sélectif des sinus pétreux inférieurs ou encore des sinus caverneux, le 111In pentréotide scan et le PET scan avec 18 flurodéoxyglucose hypophysaires. Dans cet article, nous passons en revues les méthodes de diagnostic biologique de la maladie de Cushing et des adénomes corticotropes, les diagnostics différentiels ainsi que le traitement médical selon notre expérience et les données les plus récentes de la littérature.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

Beckers, Albert ; Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie

Valdes Socin, Hernan Gonzalo ; Université de Liège - ULiège > Endocrinologie clinique

Betea, Daniela ; Centre Hospitalier Universitaire de Liège - CHU > Endocrinologie clinique

Stevenaert, Achille ; Centre Hospitalier Universitaire de Liège - CHU > Neurochirurgie

Language :

French

Title :

Diagnostic differentiel et traitement medical dans la maladie de Cushing.

Alternative titles :

[en] Differential diagnosis and medical treatment in Cushing's disease

Publication date :

May 2002

Journal title :

Neuro-Chirurgie

ISSN :

0028-3770

Publisher :

Masson, Paris, France

Volume :

Issue :

2-3 Pt 2

Pages :

163-172

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 21 June 2010

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Bibliography

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