Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.

Pierard, Claudine; Colige, Alain; Arrese Estrada, Jorge; Lapiere, C. M.; Pierard, Gérald

doi:10.1159/000247623

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Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.

Pierard, Claudine; Colige, Alain; Arrese Estrada, Jorge et al.

1991 • In Dermatologica, 183 (1), p. 7-9

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/62645

DOI
10.1159/000247623

PubMed
1769424

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Keywords :

Cell Membrane/chemistry; Cell Nucleus/chemistry; Humans; Immunohistochemistry; Keratinocytes/chemistry/ultrastructure; Receptor, Epidermal Growth Factor/analysis; Sweat Glands/chemistry/ultrastructure

Abstract :

[en] We have raised a polyclonal antibody to the 170-kD epidermal growth factor receptor. We found an intercellular pattern of immunoreactivity in the epidermis as well as a positivity of the cytoplasm of keratinocytes and eccrine secretory cells. In some samples, a nuclear labelling was evidenced in these type of cells. There is a close resemblance in the topographical distribution of these cells with nuclear labelling and those synthesizing DNA under phytohaemagglutinin stimulation.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Pierard, Claudine ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Colige, Alain ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Laboratoire des tissus conjonctifs

Arrese Estrada, Jorge ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Lapiere, C. M.

Pierard, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Language :

English

Title :

Immunohistochemical expression of epidermal growth factor receptors in nuclei of a subpopulation of keratinocytes and sweat gland cells.

Publication date :

1991

Journal title :

Dermatologica

ISSN :

0011-9075

Publisher :

Karger, Basel, Switzerland

Volume :

183

Issue :

Pages :

7-9

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 18 June 2010

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Bibliography

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