[en] The diversity of substances used illegally as growth promoters in meat production requires the development of multi-analyte methods of analysis involving a sample pretreatment step that is as rapid and as easy as possible, followed by a specific and sensitive determination of several residues within the same run. A general strategy for the screening and confirmatory analysis of fifteen artificial anabolic compounds in urine samples is described. It is based on solid-phase extraction on C18 Empore discs and amino-bonded columns followed, after derivatization (trimethylsilyl or methyloxime-trimethylsilyl derivatives), by gas chromatography coupled with collisionally activated dissociation tandem mass spectrometry.
Disciplines :
Chemistry Food science
Author, co-author :
Van Vyncht, G.
Gaspar, P.
De Pauw, Edwin ; Université de Liège - ULiège > Chimie physique, spectrométrie de masse
Maghuin-Rogister, Guy ; Université de Liège - ULiège > Département de sciences des denrées alimentaires > Département de sciences des denrées alimentaires
Language :
English
Title :
Multi-Residue Screening and Confirmatory Analysis of Anabolic Steroids in Urine by Gas Chromatography Coupled with Tandem Mass Spectrometry
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