Article (Scientific journals)
A propos d'une analyse retrospective parue dans Lancet sur les benefices de la chirurgie des stenoses carotidiennes symptomatiques. L'importance de definir ce dont on parle
Van Damme, Hendrik; Limet, Raymond
2005In Revue Médicale de Liège, 60 (9), p. 737-40
Peer reviewed
 

Files


Full Text
272.pdf
Publisher postprint (719.62 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] It is important to establish clear definitions concerning carotid artery disease, a topic that recently regained widespread interest in medical literature. Therefore, we summarize a paper of Rothwell and Barnett, recently published in the Lancet 2003 (1). In their analysis, the data of three randomized trials, comparing carotid endarterectomy to optimal medical therapy alone for a symptomatic internal carotid artery stenosis, were pooled after standardization of the measurement of the degree of stenosis and redefinition of the outcome events, to achieve comparability of the results of each trial. This analysis concerns 6092 patients with 35,000 patient-years of follow-up. Surgery offers a marginal benefit for patients with a moderate (50-69%) symptomatic carotid artery stenosis (absolute risk reduction of 4.6% for subsequent ipsilateral stroke at 5 years). Surgery is highly beneficial for patients with a symptomatic 70-99% stenosis (absolute risk reduction of 16% for ipsilateral stroke at 5 years). The benefit is uncertain for a symptomatic "near occlusion" (99% with retarded opacification of the distal internal carotid artery): absolute risk reduction of -1.7% for ipsilateral stroke at 5 years).
Disciplines :
Surgery
Author, co-author :
Van Damme, Hendrik ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Limet, Raymond ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique
Language :
French
Title :
A propos d'une analyse retrospective parue dans Lancet sur les benefices de la chirurgie des stenoses carotidiennes symptomatiques. L'importance de definir ce dont on parle
Alternative titles :
[en] Analysis of Pooled Data from the Randomized Controlled Trials of Endarterectomy for Symptomatic Carotid Stenosis
Publication date :
September 2005
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Volume :
60
Issue :
9
Pages :
737-40
Peer reviewed :
Peer reviewed
Available on ORBi :
since 25 February 2011

Statistics


Number of views
142 (4 by ULiège)
Number of downloads
226 (1 by ULiège)

Scopus citations®
 
8
Scopus citations®
without self-citations
7

Bibliography


Similar publications



Contact ORBi