Reference : Positron emission tomography (PET) evaluation of abdominal aortic aneurysm (AAA)
Scientific journals : Article
Human health sciences : Surgery
Positron emission tomography (PET) evaluation of abdominal aortic aneurysm (AAA)
SakalihasanN, Natzi mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie cardio-vasculaire]
Van Damme, Hendrik mailto [Université de Liège - ULiège > Département des sciences cliniques > Service de chirurgie cardio-vasculaire > >]
Gomez, P. [> > > >]
Rigo, Pierre mailto [Université de Liège - ULiège > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
Lapiere, C. M. [> > > >]
Nusgens, Betty mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Laboratoire de Biologie des Tissus Conjonctifs > >]
Limet, Raymond [Université de Liège - ULiège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique]
European Journal of Vascular and Endovascular Surgery
Yes (verified by ORBi)
United Kingdom
[en] Aged ; Aorta, Abdominal/metabolism/surgery ; Aortic Aneurysm, Abdominal/metabolism/radionuclide imaging/surgery ; Aortic Rupture/metabolism/radionuclide imaging/surgery ; Back Pain/etiology ; emission-computed ; Fluorodeoxyglucose F18/diagnostic use ; Image Enhancement ; Lung Neoplasms/mortality/radionuclide imaging ; metalloendopeptidases ; Tomography, Emission-Computed ; Treatment Outcome ; Vascular Surgical Procedures
[en] Background: aneurysmal disease is associated with all inflammatory Cell infiltrate and enzymatic degradation of the vessel wall. Aim of the study: to detect increased metabolic activity in abdominal aortic aneurysms (AAA) by means of positron emission tomography (PET-imaging). Study design: twenty-six patients with AAA underwent PET-imaging Results: in tell patients, PET-imaging revealed increased, fluoro-deoxy-glucose (18-FDG) uptake at the level of the aneurysm. Patients with positive PET-imaging had one or more of the following elements in their clinical history: history Of recent non-aortic surgery (n = 4) a painful inflammatory aortic aneurysm (n = 2). moderate low back pain (n = 2), rapid (>5 mm in 6 months) expansion (n = 4), discovery by PET-scan of a previously undiagnosed lung cancer (n = 3) or parotid tumour (n = 1). Five patients with a positive PET scan required urgent surgery within two to 30 days. Among the 16 patients with negative PET-imaging of their aneurysm, only one had recent non-aortic surgery, none of them required urgent surgery, only two had a rapidly expanding AAA, and in only one patient, PET-imaging revealed an unknown lung cancer. Conclusion: these data suggest a possible association between increased 18-FDG uptake and AAA expansion and rupture.
Researchers ; Professionals
original publication available in Eur J Vasc Endovasc Surg

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