Strychnos usambarensis; dihydrousambarine; usambaridines; strychnobaridine; strychnopentamine; isostrychnopentamines A and B
Abstract :
[en] Fourteen bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. Nine are described here for the frst time: 18,19-dihydro-usambarine; usambaridines and their dihydroderivatives; strychnobaridine; strychnopentamine and isomers. The elucidation of structure and the stereochemistry of these new compounds are also discussed. They possess the "usambarane" skeleton; moreover many are phenolic and amongst them, strychnopentamine and isomers are curiuos alkaloids with five nitrogen atoms: a methylpyrrolidine group is joined to the indole ring of the corynane part of the molecule.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Coune, Claude
Tits, Monique ; Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Language :
French
Title :
Nouveaux alcaloïdes des feuilles de Strychnos usambarensis
Alternative titles :
[en] New alkaloids from Strychnos usambarensis leaves
