Article (Scientific journals)
Nouveaux alcaloïdes des feuilles de Strychnos usambarensis
Angenot, Luc; Coune, Claude; Tits, Monique
1978In Journal de Pharmacie de Belgique, 33 (1), p. 11-23
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Keywords :
Strychnos usambarensis; dihydrousambarine; usambaridines; strychnobaridine; strychnopentamine; isostrychnopentamines A and B
Abstract :
[en] Fourteen bis-indole alkaloids have been isolated from Strychnos usambarensis leaves. Nine are described here for the frst time: 18,19-dihydro-usambarine; usambaridines and their dihydroderivatives; strychnobaridine; strychnopentamine and isomers. The elucidation of structure and the stereochemistry of these new compounds are also discussed. They possess the "usambarane" skeleton; moreover many are phenolic and amongst them, strychnopentamine and isomers are curiuos alkaloids with five nitrogen atoms: a methylpyrrolidine group is joined to the indole ring of the corynane part of the molecule.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Coune, Claude
Tits, Monique ;  Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Language :
French
Title :
Nouveaux alcaloïdes des feuilles de Strychnos usambarensis
Alternative titles :
[en] New alkaloids from Strychnos usambarensis leaves
Publication date :
1978
Journal title :
Journal de Pharmacie de Belgique
ISSN :
0047-2166
Publisher :
Nationale Pharmaceutique, Bruxelles, Belgium
Volume :
33
Issue :
1
Pages :
11-23
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 04 May 2010

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