Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I

[en] Background/Aims: The aim of this study was to identify neuropsychiatric subsyndromes of the Neuropsychiatric Inventory in a large sample of outpatients with Alzheimer's disease (AD). Methods: Cross-sectional data of 2,354 patients with AD from 12 centres from the European Alzheimer's Disease Consortium were collected. Principal component analysis was used for factor analysis. Results: The results showed the presence of 4 neuropsychiatric subsyndromes: hyperactivity, psychosis, affective symptoms and apathy. The subsyndrome apathy was the most common, occurring in almost 65% of the patients. Conclusion: This large study has provided additional robust evidence for the existence of neuropsychiatric subsyndromes in AD. Copyright (c) 2007 S. Karger AG, Basel.

Disciplines :

Sociology & social sciences
Geriatrics
Neurology

Author, co-author :

Aalten, Pauline; Maastricht University Hospital > Alzheimer Centre Limburg > Department of Psychiatry and Neuropsychology

Verhey, Frans R. J.; Maastricht University Hospital > Alzheimer Centre Limburg > Department of Psychiatry and Neuropsychology

Boziki, Marina

Bullock, Roger

Byrne, Eleanor Jane

Camus, Vincent

Caputo, Miriam

Collins, Debby

De Deyn, Peter Paul

Elina, Kazi

More authors (13 more)

Language :

English

Title :

Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I

Publication date :

2007

Journal title :

Dementia and Geriatric Cognitive Disorders

ISSN :

1420-8008

eISSN :

1421-9824

Publisher :

Karger, Basel, Switzerland

Volume :

Issue :

Pages :

457-463

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstract&ArtikelNr=110738&Ausgabe=234104&ProduktNr=224226

Funders :

F.R.S.-FNRS - Fonds de la Recherche Scientifique
EADC - European Alzheimer's Disease Consortium

Available on ORBi :

since 28 January 2009

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318

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