[en] Porcine follicle stimulating hormone (pFSH) and porcine luteinizing hormone (pLH), are widely used to induce superovulation in cows. An advantage of this treatment is that the LH:FSH ratio can be varied to optimize the growth of the ovarian follicles. However, due to the relatively short half-life of FSH, the superovulatory treatment requires numerous injections.
A performant radioimmunoassay system (sensitivity=0.2 ng/ml plasma) was used to determine plasma pFSH levels in cows that were superovulated with 2 daily injections of 4 Armour Units (A.U.) of pFSH for 4 d. From plasma profiles, the half-life and the disappearance of pFSH were estimated at 5 h and at 10 to 12 h, respectively, confirming the necessity of using two daily injections.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Demoustier, M.; Université Catholique de Louvain - UCL > Laboratoire de Pharmacie Galénique
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Van Der Zwalmen, P.; Université de Liège - ULiège > Obstétrique et troubles de la reproduction - Faculté de Médecine Vétérinaire
Closset, Jean ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie générale, humaine et pathologique
Gillard, J. L.; Université Catholique de Louvain - UCL > Laboratoire de Pharmacie Galénique
Ectors, Francis ; Université de Liège - ULiège > Faculté de médecine vétérinaire
Language :
English
Title :
Determination of porcine plasma follitropin levels during superovulation treatment in cows
Publication date :
August 1988
Journal title :
Theriogenology
ISSN :
0093-691X
eISSN :
1879-3231
Publisher :
Elsevier, New York, United States - New York
Volume :
30
Issue :
2
Pages :
379-386
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
IRSIA - Institut pour l'Encouragement de la Recherche Scientifique dans l'Industrie et l'Agriculture [BE]
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