Reference : Actualite sur les effets de la vitamine D et l'evaluation du statut vitaminique D.
Scientific journals : Article
Human health sciences : Urology & nephrology
Human health sciences : General & internal medicine
Human health sciences : Endocrinology, metabolism & nutrition
Actualite sur les effets de la vitamine D et l'evaluation du statut vitaminique D.
[en] Update on vitamin D and evaluation of vitamin D status.
Souberbielle, Jean-Claude [> > > >]
Prié, Dominique [ > > ]
Courbebaisse, Marie [> > > >]
Friedlander, Gérard [> > > >]
Houillier, Pascal [> > > >]
Maruani, G. [> > > >]
Cavalier, Etienne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Cormier, Catherine [> > > >]
Annales d'Endocrinologie
Yes (verified by ORBi)
Moulineaux Cedex 9
[en] Knowledge about vitamin D has greatly improved during the last few years. Vitamin D cannot any more be considered as exclusively necessary to prevent ricket/osteomalacia. Its role in the prevention of some osteoporotic fractures in the elderly (in association with calcium nutrition) is now well demonstrated and many epidemiologic and laboratory data argue for a role in the prevention of several diseases or anomalies (cancer, auto-immune diseases, cardiovascular events, sarcopenia...). A few intervention studies confirming some of these effects also exist. Vitamin D status can easily be assessed by measuring serum 25 hydroxy vitamin D (25OHD) level. However, many experts have claimed that the population-based reference values for 25OHD are too low and that the cut-off value below which vitamin D insufficiency can be present is somewhere between 20 and 40ng/mL with a clear tendency to target values above 30ng/mL (75nmol/L). The main consequences are that vitamin D insufficiency is highly frequent whereas the currently recommended supplementation doses are not sufficient.
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