[en] Knowledge about vitamin D has greatly improved during the last few years. Vitamin D cannot any more be considered as exclusively necessary to prevent ricket/osteomalacia. Its role in the prevention of some osteoporotic fractures in the elderly (in association with calcium nutrition) is now well demonstrated and many epidemiologic and laboratory data argue for a role in the prevention of several diseases or anomalies (cancer, auto-immune diseases, cardiovascular events, sarcopenia...). A few intervention studies confirming some of these effects also exist. Vitamin D status can easily be assessed by measuring serum 25 hydroxy vitamin D (25OHD) level. However, many experts have claimed that the population-based reference values for 25OHD are too low and that the cut-off value below which vitamin D insufficiency can be present is somewhere between 20 and 40ng/mL with a clear tendency to target values above 30ng/mL (75nmol/L). The main consequences are that vitamin D insufficiency is highly frequent whereas the currently recommended supplementation doses are not sufficient.
Disciplines :
Endocrinology, metabolism & nutrition Urology & nephrology General & internal medicine
Author, co-author :
Souberbielle, Jean-Claude
Prié, Dominique
Courbebaisse, Marie
Friedlander, Gérard
Houillier, Pascal
Maruani, G.
Cavalier, Etienne ; Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale
Cormier, Catherine
Language :
French
Title :
Actualite sur les effets de la vitamine D et l'evaluation du statut vitaminique D.
Alternative titles :
[en] Update on vitamin D and evaluation of vitamin D status.
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