Reference : Folipidine, a new type quinoline alkaloid from plants of the Haplophyllum genus
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
Folipidine, a new type quinoline alkaloid from plants of the Haplophyllum genus
Akhmedzhanova, V. I. [> > > >]
Rasulova, K. A. [> > > >]
Bessonova, I. A. [> > > >]
Shashkov, A. S. [> > > >]
Abdullaev, N. D. [> > > >]
Angenot, Luc mailto [Université de Liège - ULiège > Département de pharmacie > Pharmacognosie >]
Chemistry of Natural Compounds
Kluwer Academic/Plenum Publishers
Yes (verified by ORBi)
New York
[en] Haplophyllum foliosum ; H. pedicellatum ; Rutaceae ; new quinoline alkaloid folipidine ; chemical transformations ; spectral data (UV, IR, mass, NMR, 2D(1)H-H-1 COSY, NOESY, H-1-C-13 HSQC, HMBC) ; antitumor activity
[en] The new quinoline alkaloid folipidine, the structure of which was established by chemical transformations and spectral data (UV, IR, mass, NMR) using APT 2D H-1-H-1 COSY, NOESY, and H-1-(13)CHSQC, HMBC, was isolated from two plants of the Haplophyllum mints. Folipidine is the first representative of a new type of quinoline alkaloids that contain a heteroaromatic skeleton of [3,4-b]conjugated pyrrole and quinoline fragments. The total alkaloids of these plants exhibit antitumor activity. Folipidine does not possess such activity.

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