[en] DNA histograms were oblained by flow cytometry for 39 human prostate carcinomas (27 total
proslatectomy specimens, 5 biopsies and 7 transuretral resections). The study was performed on
formalin-fixed and paraffin-embedded. material. In this report, ploidy index did not seem to be a good
marker of prognosis as no significant variation in ploidy was found neither among the different stages nor
among the different Gleason categories. Proliferative index of the tumors seemed to be a more sensitive
parameter; a significant relation was observed between proliferative index and stage of the tumor. The
authors discuss these results under the light of previously reported observations.
Disciplines :
Biochemistry, biophysics & molecular biology Anatomy (cytology, histology, embryology...) & physiology Laboratory medicine & medical technology
Author, co-author :
de Leval, Laurence ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques - Département des sciences biomédicales et précliniques
Waltregny, David ; Université de Liège - ULiège > Département des sciences cliniques > Urologie - GIGA-R : Labo de recherche sur les métastases
Greimers, Roland ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Boniver, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Language :
English
Title :
Cytofluorometric analysis of prostate cancer specimens: Histological and clinical correlations
