Article (Scientific journals)
Effect of hydroxyethylstarch on renal function in cardiac surgery: A large scale retrospective study
Wiesen, Patricia; Canivet, Jean-Luc; Ledoux, Didier et al.
2005In Acta Anaesthesiologica Belgica, 56 (3), p. 257-263
Peer Reviewed verified by ORBi
 

Files


Full Text
37.pdf
Publisher postprint (1.09 MB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] BACKGROUND: Recent reports indicated negative effects of hydroxyethylstarch (HES) on renal function. The goal of this large scale retrospective study was to detect whether there was an association between postoperative deterioration of renal function and the use of HES 200 kD, 0.5 DS in the cardiac surgery setting. METHODS: Retrospective analysis of daily collected data in 3124 patients who underwent coronary artery bypass and/or valvular surgery. Three groups were compared according to differences in fluid therapy: --GEL: gelatin was used as priming fluid of extracorporeal circulation (ECC) and for postoperative filling (n = 1276). --MIX: HES was used as priming fluid of ECC an gelatin was used for postoperative filling (n = 1008). --HES: HES was used as priming fluid of ECC and for postoperative filling (n = 840). MAIN RESULTS: There were no significant differences in postoperative serum creatinine concentrations between the 3 groups: GEL: 12,2 +/- 0,5 mg/l; MIX: 12,3 +/- 0.5 mg/l; HES: 12,3 +/- 0.6 mg/l. The need for postoperative extrarenal epuration was not significantly different between the 3 periods: GEL: 2,9%; MIX: 3,1%; HES: 3,8%. CONCLUSION: The use of HES 200 kD, 0.5 DS in cardiac surgery does not seem to be associated with a clinically significant deterioration of postoperative renal function.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Wiesen, Patricia ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
Canivet, Jean-Luc ;  Université de Liège - ULiège > Soins intensifs
Ledoux, Didier  ;  Centre Hospitalier Universitaire de Liège - CHU > Soins intensifs
Roediger, Laurence ;  Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Damas, Pierre ;  Université de Liège - ULiège > Soins intensifs
Language :
English
Title :
Effect of hydroxyethylstarch on renal function in cardiac surgery: A large scale retrospective study
Publication date :
2005
Journal title :
Acta Anaesthesiologica Belgica
ISSN :
0001-5164
eISSN :
2736-5239
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
56
Issue :
3
Pages :
257-263
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 February 2011

Statistics


Number of views
46 (10 by ULiège)
Number of downloads
4 (4 by ULiège)

Scopus citations®
 
17
Scopus citations®
without self-citations
17

Bibliography


Similar publications



Contact ORBi