[en] The author describes recent advances in the chemistry and the pharmacology of African Strychnos. Emphasis is given to the study of leaves of Strychnos usambarensis which contain a series of new molecules (strychnopentamine and isomers, strychnofoline and isostrychnofoline, usambaridines ( hydroxyusambarines), strychnophylline and isomer, 18,19-dihydrousambarine); moreover the revision of the structure of usambarine is demonstrated. A further novel alkaloid (akagerine ) is also identified from the roots of the same species collected in the National Park of Akagera in Rwanda. .
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
French
Title :
Nouvelles recherches sur les alcaloïdes des Strychnos africains
Alternative titles :
[en] Recent Advances in the Chemistry and the Pharmacology of the Alkaloids of African Strychnos
Publication date :
December 1976
Publisher :
Académie Royale de Médecine de Belgique, Bruxelles, Unknown/unspecified
Number of pages :
90
Commissioned by :
Académie Royale de Médecine de Belgique -Concours ordinaire de l'Académie (Ve Section, période 1974-1976)
Commentary :
This dissertation has permitted to the author to receive the Prize of the Belgian Royal Academy of Medicine - Ordinary competition- 5th Section -Period 1976-1978). See Report of the Jury in " Bulletin et Mémoires de l'Académie Royale d Médecine de Belgique Année 1977 Pages 251-252 and Report of the Awards Ceremony organized at Brussels on 18th February 1978 in "Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique" 1978, pages 132-134.
