Progres recents dans la pharmacologie des hypnotiques et anxiolytiques

Scuvée-Moreau, Jacqueline; Seutin, Vincent

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Progres recents dans la pharmacologie des hypnotiques et anxiolytiques

Scuvée-Moreau, Jacqueline; Seutin, Vincent

2001 • In Revue Médicale de Liège, 56 (3), p. 159-64

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https://hdl.handle.net/2268/37743

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Keywords :

Receptors; benzodiazepines; anxiolytic effect

Abstract :

[en] Recent studies on the respective contribution of GABAA receptor subunits in the various pharmacological effects of benzodiazepines suggest that the sedative and amnesic properties of diazepam are mediated by enhancement of gabaergic transmission in neurons expressing the alpha 1 subunit while the anxiolytic effect is selectively mediated by alpha 2 subunit. These findings suggest that a separation of the pharmacological properties of benzodiazepines is possible and that drugs with increased clinical specificity could be developed.

Disciplines :

Pharmacy, pharmacology & toxicology

Author, co-author :

Scuvée-Moreau, Jacqueline ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Pharmacologie - Département des sciences biomédicales et précliniques

Seutin, Vincent ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Pharmacologie

Language :

French

Title :

Progres recents dans la pharmacologie des hypnotiques et anxiolytiques

Alternative titles :

[en] Recent Progress in the Pharmacology of Hypnotics and Anxiolytics

Publication date :

March 2001

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

Issue :

Pages :

159-64

Available on ORBi :

since 20 May 2010

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Bibliography

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