Interrelationship of Hypertension, Plasma Lipids and Atherosclerosis

[en] The relationship between hypertension and atherosclerosis has been illustrated by epidemiological, clinical and experimental observations. Typical atherosclerotic lesions develop in arterial wall when hypercholesterolaemia is present. Hypertension aggravates these lesions by causing vascular structural changes. In clinical studies, however, the correction of high blood pressure does not decrease the incidence of coronary heart disease. Several hypotheses have been formulated to account for this observation: one is that reversibility of the structural vascular changes induced by hypertension is not complete when the blood pressure is lowered; another is that antihypertensive drugs have a deleterious effect on the vascular wall.

Disciplines :

Urology & nephrology

Author, co-author :

Krzesinski, Jean-Marie ; Université de Liège - ULiège > Département des sciences cliniques > Néphrologie

Carlier, P. G.; National Fund for Scientific Research, Belgium

Rorive, G. L.; National Fund for Scientific Research, Belgium

Language :

English

Title :

Interrelationship of Hypertension, Plasma Lipids and Atherosclerosis

Publication date :

1988

Journal title :

Drugs

ISSN :

0012-6667

eISSN :

1179-1950

Publisher :

Adis International, United Kingdom

Volume :

Issue :

Suppl 2

Pages :

18-26

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 19 May 2010

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