Strychnos usambarensis; Melinonine F; Strychnofoline; 18,19-dihydrousambarine; cancer cells; antimitotic activity
Abstract :
[en] The cellular effects of three alkaloids isolated from STRYCHNOS USAMBARENSIS (melinonine F, strychnofoline, 18-19-dihydro-usambarine) are analysed by cytological methods in experimental animal tumours cultivated IN VITRO (B 16 mouse melanoma cells, mouse Ehrlich tumour cells ELT, HW 165 rat hepatoma). Under some experimental conditions, a certain degree of antimitotic activity is demonstrated.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Bassleer, Roger ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)
De Pauw-Gillet, Marie-Claire ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie - Département des sciences biomédicales et précliniques
Massart, B.
Marnette, J. M.
Wiliquet, P.
Caprasse, M.
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
French
Title :
Effets de trois Alcaloides Extraits du Strychnos usambarensis sur des Cellules Cancereuses en Culture
Alternative titles :
[en] Effects of Three Alkaloids Isolated from Strychnos Usambarensis on Cancer Cells in Culture.
