[en] High Speed Counter Current Chromatography (HSCCC) has been used to isolate and purify two quaternary alkaloids from a sample of curare prepared by the Panare Indians of Estado Bolivar, Venezuela. One of the compounds is the known base Macusine B. The other one is a new but related base named panarine. Its structure has been established unequivocally by spectral and X-ray cristallographic analysis.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Quetin-Leclercq, Joëlle
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Dupont, Léon
Bisset, Norman
Language :
English
Title :
Isolation and Purification of Panarine, a Quaternary Alkaloid from a Venezuelian Curare
Publication date :
1988
Journal title :
Phytochemistry
ISSN :
0031-9422
eISSN :
1873-3700
Publisher :
Pergamon Press, New York, United States - New York
