[en] Usambarensine is a bisindolinic alkaloid found in the bark of Strychnos usambarensis roots. The crystal and molecular structure of usambarensine.2HBr.2H2O has been solved by direct methods thanks to a Hilger-Watts four-circle diffractometer. The crystals are monoclinic; refinement of the parameters was carried out with 2459 reflexions. The absolute configuration of the molecule, determined by X-ray anomalous scattering, confirms the 3 alpha cis configuration ( 11alpha cis, IUPAC) assigned earlier by spectral, chromatographic and biogenetic data.This configuration seems dependent on the presence of an ethylidenic chain in the corynane part of the molecule.
Disciplines :
Pharmacy, pharmacology & toxicology Physics
Author, co-author :
Dideberg, Otto
Dupont, Léon
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
French
Title :
Détermination de la Structure Cristalline et de la Configuration Absolue du Bromhydrate d'Usambarensine
Alternative titles :
[en] Crystal Structure and Absolute Configuration of Usambarensine Hydrobromide
Publication date :
1975
Journal title :
Acta Crystallographica. Section B, Structural Crystallography and Crystal Chemistry
ISSN :
0567-7408
Publisher :
Munksgaard International Publishers, Copenhagen, Denmark
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.