[en] Correction to: Nature Reviews Rheumatologyhttps://doi.org/10.1038/s41584-025-01287-w, published online 11 August 2025. In the version of the article initially published, in Fig. 1, the box reading “↑ OPG” should have read “↓ OPG”. In the Fig. 1 caption, the text “..results in increased expression of receptor activator of NF-ᴋB ligand (RANKL) and osteoprotegerin (OPG) in osteoclasts, and sustained RANKL–OPG signalling supports osteoclast activation, resulting in bone resorption” should have read “..results in increased expression of receptor activator of NF-ᴋB ligand (RANKL) and downregulation of osteoprotegerin (OPG) in osteoclasts, leading to osteoclast activation, and resultant bone resorption”. These corrections have now been made to the HTML and PDF versions of the article.
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
Fuggle, Nicholas ; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK
Rizzoli, René ; Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland
Beaudart, Charlotte; Public Health Aging Research & Epidemiology (PHARE) Group, Research Unit in Clinical Pharmacology and Toxicology (URPC), NAmur Research Institute for LIfe Sciences (NARILIS), University of Namur, Namur, Belgium
Cortet, Bernard; Department of Rheumatology, University-Hospital of Lille, Lille, France
Curtis, Elizabeth M; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK
Hiligsmann, Mickaël; Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Maastricht University, Maastricht, Netherlands
Kaufman, Jean-Marc; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium
Veronese, Nicola ; Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia ; Saint Camillus International University of Health Sciences, Rome, Italy
Albergaria, Ben Hur; Espirito Santo Research and Osteoporosis Center, Federal University of Espirito Santo, Vitória, Brazil
Al-Daghri, Nasser; Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
Alokail, Majed; Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
Brandi, Maria Luisa ; University Vita-Salute San Raffaele, Milan, Italy ; FIRMO Foundation, Florence, Italy
Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Burlet, Nansa ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé ; The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), Liege, Belgium
Campusano, Claudia; Department of Internal Medicine, Clínica Universidad de los Andes, Universidad de los Andes, Santiago, Chile ; School of Medicine, Universidad de los Andes, Santiago, Chile
Casado, Enrique ; Department of Rheumatology, Parc Taulí Hospital Universitari, Universitat Autònoma de Barcelona, Sabadell, Spain ; Institut d'Investigació i Innovació Parc Taulí (I3PT-CERCA). Universitat Autònoma de Barcelona, Sabadell, Spain
Cavalier, Etienne ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale
Chandran, Manju; Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital, Singapore, Singapore ; DUKE NUS Medical School, Singapore, Singapore
Cooper, Cyrus ; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK ; NIHR Southampton Biomedical Research Centre, University of Southampton, Southampton, UK ; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK
D'Amelio, Patrizia; Department of Geriatrics and Geriatric Rehabilitation, Lausanne University Hospital, Lausanne, Switzerland
Dawson-Hughes, Bess; Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, USA
Ebeling, Peter R ; Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia
Kanis, John A; Centre for Integrated Research in Musculoskeletal Ageing, Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK
Kurth, Andreas; Johann Wolfgang Goethe University, Frankfurt, Germany
Matijevic, Radmila; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia ; Clinic for Orthopedic Surgery and Traumatology, University Clinical Center of Vojvodina, Novi Sad, Serbia
McCloskey, Eugene ; Centre for Integrated Research in Musculoskeletal Ageing, Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, UK
McClung, Michael; Oregon Osteoporosis Center, Portland, OR, US
Mkinsi, Ouafa; Rheumatology Department, Ibn Roch University Hospital, Casablanca, Morocco
Njeze, Ngozi; Department of Radiation Medicine, University of Nigeria Medical School, Nsukka, Nigeria
Radermecker, Régis ; Université de Liège - ULiège > Département des sciences cliniques > Pharmacologie clinique
Rannou, François; Service de Rééducation et de Réadaptation de l'Appareil Locomoteur et des Pathologies du Rachis, Hôpital Cochin, Assistance publique - hôpitaux de Paris, Centre-Université Paris Cité, Paris, France
Silverman, Stuart; OMC Clinical Research Center, Beverly Hills, CA, USA ; Cedars-Sinai Medical Center, Beverly Hills, CA, USA
Tüzün, Şansın; Department of Physical Medicine and Rehabilitation, Cerrahpaşa School of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey
Zakraoui, Leith; Department of Rheumatology, University of Tunis El Manar, Tunis, Tunisia
Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique ; Biochemistry Department, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia
Harvey, Nicholas C ; MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK. nch@mrc.soton.ac.uk ; NIHR Southampton Biomedical Research Centre, University of Southampton, Southampton, UK. nch@mrc.soton.ac.uk