GC-Suited Sample Preparation Approaches for Omics Studies

Franchina, Flavio; Pierret, Damien; Purcaro, Giorgia

doi:10.1002/9781394209309.ch2

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GC-Suited Sample Preparation Approaches for Omics Studies

Franchina, Flavio; Pierret, Damien; Purcaro, Giorgia

2026 • In Gas Chromatography-Mass Spectrometry for Omics Applications

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https://hdl.handle.net/2268/347937

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10.1002/9781394209309.ch2

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Keywords :

dynamic headspace (DHS); liquid-phase extractions (LPE); miniaturization, thermal desorption tubes (TDT); semivolatile organic compounds (sVOC); solid-phase extraction (SPE); static headspace (SHS); volatile organic compounds (VOC); Dynamic headspace; Liquid phase extraction; Liquid-phase extraction; Miniaturisation; Miniaturization, thermal desorption tube; Semivolatile organic compound; Semivolatile organic compounds; Solid-phase extraction; Static headspace; Thermal; Volatile organic compound; Volatile organics; Chemistry (all); Biochemistry, Genetics and Molecular Biology (all)

Abstract :

[en] Despite the advances in separation and detection techniques, sample processing is still the basis for chemical analyses, in which effective sample extraction and clean-up are necessary to achieve reliable results. Indeed, sample preparation is the critical step before analysis as it can significantly affect selectivity, sensitivity, and reproducibility. Generic sample preparation protocols are lacking in this fast-growing analytical field, and a fine balance must be tuned between ensuring elimination of interferences and not excluding chemical domains from the analysis. This chapter will give insights into the evaluation of sample preparation approaches suitable for analysis of volatile and semivolatile compounds.

Disciplines :

Chemistry
Life sciences: Multidisciplinary, general & others

Author, co-author :

Franchina, Flavio ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie analytique, organique et biologique ; Department of Chemical Pharmaceutical, and Agricultural Sciences, University of Ferrara, Ferrara, Italy

Pierret, Damien ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)

Purcaro, Giorgia ; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)

Language :

English

Title :

GC-Suited Sample Preparation Approaches for Omics Studies

Publication date :

May 2026

Main work title :

Gas Chromatography-Mass Spectrometry for Omics Applications

Publisher :

wiley

ISBN/EAN :

978-1-394-20930-9
978-1-394-20927-9

Peer reviewed :

Peer reviewed

Additional URL :

https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781394209309.ch2

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since 17 August 2026

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