Continuous intravenous lidocaine infusion; Douleur chronique viscérale; Multimodal protocols; Neuropathie périphérique; Perfusion intraveineuse continue de lidocaïne; Peripheral neuropathy; Protocoles multimodaux; Systemic use of lidocaine; Utilisation systémique de la lidocaïne; Visceral chronic pain; Emergency Medicine; Emergency Nursing; Anesthesiology and Pain Medicine
Abstract :
[en] Systemic lidocaine, widely used for postoperative surgical pain prophylaxis, is increasingly relevant for refractory chronic pain management, particularly visceral pain. This review explores its practical applications in peripheral neuropathies, complex regional pain syndromes, and chronic visceral pain resistant to other recommended molecules. Validated dosages and systemic anti-hyperalgesic and anti-inflammatory mechanisms (prolonged sodium channel blockade, voltage-gated channel modulation) are described and supported by randomized trials and meta-analyses demonstrating the benefit of this indication. Clinical monitoring strategies (continuous ECG, prior hepatic function assessment) and contraindications (arrhythmias, heart failure) are specified for safe use in outpatient or inpatient settings. The complementary role of this molecule in multimodal protocols (antiepileptics, antidepressants, and enhanced recovery programs) is also addressed. This synthesis aims to guide clinicians toward this promising extension of its practical use.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Lejeune, Delphine ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation ; Fondation Léon Fredericq, Belgium
Thierry, Gabriel ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation ; Groupe francophone de réhabilitation améliorée après chirurgie (GRACE® , Francophone Group for Enhanced Recovery after Surgery), Beaumont, France
Kaba, Abdourhamane; Département d’anesthésie et réanimation, centre hospitalier universitaire de Liège, Liège, Belgium ; Centre de recherche et d’enseignement du département de chirurgie (CREDEC), centre hospitalier universitaire de Liège, GIGA Institute, université of Liège, Liège, Belgium ; Groupe francophone de réhabilitation améliorée après chirurgie (GRACE® , Francophone Group for Enhanced Recovery after Surgery), Beaumont, France
Bonhomme, Vincent ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Hans, Grégory ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Language :
French
Title :
Place de la lidocaïne intraveineuse dans le traitement de la douleur aiguë et chronique
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