e-nose, Sampling, Breath, Lung cancer, Metal oxide
Disciplines :
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others
Author, co-author :
Martin, Justin ; Université de Liège - ULiège > Sphères ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM)
Liégeois, Simon-Pierre ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM)
Jalloh, Muhamad Bailor ; Université de Liège - ULiège > Sphères ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM)
Rosiers, Mauri ; Université de Liège - ULiège > Sphères ; ULiège. Arlon Campus Environnement - Liège Université. Arlon Campus Environnement > Sensinf of Atmospheres and Monitoring
Falzone, Claudia ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM) ; Université de Liège - ULiège > Sphères
Henriche, Jean-François ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM) ; Université de Liège - ULiège > Sphères
Romain, Anne-Claude ; Université de Liège - ULiège > Département des sciences et gestion de l'environnement (Arlon Campus Environnement) > Sensing of Atmospheres and Monitoring (SAM)
Language :
English
Title :
Enhancing Electronic Nose Performance in Clinical Breath Analysis Through Sampling Design
Publication date :
20 May 2026
Event name :
International symposium on e-nose (ISOEN)
Event organizer :
International symposium on e-nose and chemical sensing (ISOCS)
Event place :
Chongqing, China
Event date :
17-20 mai 2026
Audience :
International
Peer review/Selection committee :
Peer reviewed
References of the abstract :
Electronic noses (e-noses) have shown promise for non-invasive lung cancer screening through the analysis of
volatile organic compounds (VOCs) in exhaled breath, yet clinical translation remains limited by pre-analytical
variability. This study investigates the influence of flexible polymer components, pumping strategies, and sampling bag reuse on VOC retention and contamination. It focuses on sampling-induced variability, rather than solely on sensor performance or data analysis. Controlled experiments using thermal desorption gas chromatography–mass spectrometry (TD-GCMS) evaluated VOC retention and residual contamination are presented. Results show that membrane pumps significantly increase variability and that bag washing cannot reliably eliminate contamination at low concentrations. These findings support the use of single-use bags, minimized storage times, and pump-free transfer to improve robustness of clinical e-nose breath sampling workflows.
