Article (Scientific journals)
Enhancing ECG disease detection accuracy through deep learning models and P-QRS-T waveform features.
Nayyab, Rida; Waris, Asim; Zaheer, Iqra et al.
2025 • In PLoS ONE, 20 (6), p. 0325358
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Keywords :
Humans; Neural Networks, Computer; Signal Processing, Computer-Assisted; Wavelet Analysis; Deep Learning; Electrocardiography/methods; Arrhythmias, Cardiac/diagnosis; Cardiovascular Diseases/diagnosis; Cardiovascular Diseases/physiopathology; Arrhythmias, Cardiac; Cardiovascular Diseases; Electrocardiography; Multidisciplinary
Abstract :
[en] Cardiovascular diseases (CVDs) have surpassed cancer and become the major cause of death worldwide. An electrocardiogram (ECG) is a non-invasive and quicker method for diagnosing abnormal heart conditions. While research has extensively focused on ECG analysis for disease classification, it has been primarily directed toward binary classification or classification of Arrhythmias, highlighting the dire need for detailed classification models. This study utilises the extensive PTB-XL database ECG records to develop a robust method for classifying various heart abnormalities. The data with unique labels is filtered through the Butterworth bandpass filter and Discrete Wavelet Transform (DWT) db-8. The R-peaks of the clean signal were used to detect the subsequent morphological features, i.e., P-QRS-T intervals and amplitudes. The feature set was balanced using the Synthetic Minority Oversampling Technique for Nominal and Continuous (SMOTE-NC) and fed into Convolutional Neural Network (CNN) and Deep Neural Network (DNN) with 5-fold cross-validation. The models classified the ECG records into one normal and four abnormal classes: Conduction Disturbance (CD), Myocardial Infarction (MI), Hypertrophy (HYP), and ST-T Changes (STTC). Performance metrics such as F1 score, recall, precision, and accuracy were evaluated for each model. The CNN model achieved a mean accuracy of 81% ± 0.03, while the DNN model achieved a mean accuracy of 84% ± 0.01. One key finding is that Hypertrophy (HYP) was consistently classified with up to 98% accuracy. Thus, the study demonstrates the effectiveness of combining advanced signal processing and deep learning techniques for precise multi-class heart disease classification using P-QRS-T features, paving the way for future real-time clinical applications.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Nayyab, Rida ;  Department of Biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad, Pakistan
Waris, Asim;  Department of Biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad, Pakistan
Zaheer, Iqra;  Department of Biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad, Pakistan
Khan, Muhammad Jawad;  Department of Electrical Engineering, School of Engineering, Prince Sattam Bin Abdul Aziz University, Saudi Arabia
Hazzazi, Fawwaz;  Department of Electrical Engineering, College of Engineering, Prince Sattam Bin Abdul Aziz University, Al-Kharj, Saudi Arabia
Ijaz, Muhammad Adeel ;  Department of Biomedical Engineering and Sciences, School of Mechanical and Manufacturing Engineering, National University of Sciences and Technology (NUST), Islamabad, Pakistan
Ashraf, Hassan  ;  Université de Liège - ULiège > Aérospatiale et Mécanique (A&M)
Gilani, Syed Omer ;  Department of Electrical, Computer, and Biomedical Engineering, Abu Dhabi University, Abu Dhabi, United Arab Emirates
Language :
English
Title :
Enhancing ECG disease detection accuracy through deep learning models and P-QRS-T waveform features.
Publication date :
2025
Journal title :
PLoS ONE
eISSN :
1932-6203
Publisher :
Public Library of Science
Volume :
20
Issue :
6
Pages :
e0325358
Peer reviewed :
Peer Reviewed verified by ORBi
Funding text :
Funding: This work was supported by the Abu Dhabi University ORSP grant under grant number 19300909 to author SOG.
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since 30 June 2026

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