Creatinine; kidney function; non-communicable disease; reference interval; Pathology and Forensic Medicine; Histology; Medical Laboratory Technology; Microbiology (medical)
Abstract :
[en] Median blood creatinine (Qcr) is necessary for an accurate evaluation of geriatric renal function. Nonetheless, there is a significant void in existing literature concerning creatinine reference data unique to the elderly. To improve diagnostic precision and clinical decision-making in this susceptible group, this study developed a corresponding Q model for serum creatinine in geriatric patients stratified by age and sex. To determine the Qcr serum and reference range creatinine concentrations, 913 healthy elderly patients (452 males and 461 females) undergoing routine examinations at clinical laboratories were studied. Creatinine concentration reference intervals were divided into 3 age groups, namely: 60-69 years, 70-79 years, and >80 years. The median and percentiles p2.5 (lower reference limit/LRL) and p97.5 (upper reference limit/URL) were determined by the study. The study determined the Qcr serum creatinine and reference values for the elderly, stratified by age and sex. There were no significant differences observed in creatinine level across the age group, either in males or females. Males exhibited higher creatinine compared to females (p0.05). These recently developed, ageand sex-stratified Qcr values are an invaluable tool for clinical laboratories, enabling more precise, tailored care for elderly patients with renal issues and enabling clinicians to more accurately assess geriatric renal function.
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
Marpaung, Ferdy Royland ; Doctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia ; Department of Clinical Pathology, Dr.Soetomo Academic General Hospital, Surabaya, Indonesia
Santoso, Djoko ; Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Cavalier, Etienne ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale
Aryati, Aryati; Department of Clinical Pathology, Dr.Soetomo Academic General Hospital, Surabaya, Indonesia ; Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia
Language :
English
Title :
Blood Q Creatinine Based on Sex and Age in Healthy Indonesian Geriatrics
Publication date :
20 October 2025
Journal title :
Indonesian Journal of Clinical Pathology and Medical Laboratory
ISSN :
2477-4685
eISSN :
2477-4685
Publisher :
Indonesian Association of Clinical Pathology and Laboratory Medicine
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