Article (Scientific journals)
Research Evolution on Project Management in the Pharmaceutical Sector: a Systematic Literature Review
Mroz, Kamil Dominik; Lisein, Olivier
In pressIn International Journal of Managing Projects in Business
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Keywords :
Drug Development; Pharmaceutical; Biotechnology; Project Management; Projectification; Portfolio Management; Governance; Agility; Systematic Literature Review
Abstract :
[en] This study conducts a Systematic Literature Review (SLR) of Project Management research in the pharmaceutical sector.  While project-based work has become a dominant mode of organizing, PM scholarship in the pharmaceutical industry remains fragmented and under-theorized compared to other project-intensive industries. We analyzed 136 peer-reviewed articles from 1990 to 2025 using the PRISMA protocol. The STAR Model™ (Strategy, Structure, Processes, People, Rewards) was employed as an analytical framework, enabling a multi-dimensional synthesis of how PM has been studied in the sector. The results highlight strong attention to strategy (portfolio management, governance, decision-making), structure (PMOs, maturity, adaptive models), and processes with emphasis on standardization of PM processes. By contrast, people and rewards remain comparatively neglected, despite their critical role in practice. This imbalance reveals that theoretical and empirical advances are uneven, privileging structure and strategy while under-examining human and motivational dynamics. As with all qualitative syntheses, this review has limitations. The reliance on prespecified search terms and selected journals may have excluded relevant studies in adjacent literatures or grey sources. The STAR™ framework provided structure, yet required interpretive judgment by the author, which introduces subjectivity. Despite these constraints, the review offers a systematic map of how PM in pharmaceuticals has been theorized. The findings imply that future research should expand into motivational and human-centered dimensions, employ richer empirical methods (e.g., longitudinal case studies), and build stronger connections between practice-based insights and academic theorizing. This review shows that pharmaceutical firms, as permanent organizations, increasingly depend on temporary projects, positioning project management as a strategic capability. Tracing the evolution of research helps practitioners understand how PM practices have shifted over time, recognize where the sector has lagged behind others, and draw lessons from those trajectories when implementing improvements. The COVID-19 experience underscored how agile yet compliant structures can accelerate therapies. Managers can build on these insights by leveraging PMOs and using the STAR framework as a roadmap to strengthen capabilities, enhance resilience, and increase their impact on patients and society. For society, the broader implication is that PM maturity in the pharmaceutical sector is not only a source of competitive advantage but key to drive societal value for the public good. Stronger PM capabilities can translate into more efficient decision-making in drug development, more resilient supply chains, and greater access to essential medicines, especially in global health emergencies. This is the first longitudinal SLR of pharmaceutical PM, providing a three-decade overview of how research has clustered, evolved, and where it remains underdeveloped. By positioning pharmaceutical projects as a “living laboratory” for project studies, the review demonstrates how highly regulated, knowledge-intensive, and safety-critical contexts can extend broader theories of projectification, paradox, and professionalization. The findings bridge practitioner standards with scholarly inquiry, offering actionable insights for both academics and managers.
Research Center/Unit :
LENTIC - Laboratoire d'Études sur les Nouvelles Formes de Travail, l'Innovation et le Changement - ULiège
HEC Liège Research - ULiège
Disciplines :
General management, entrepreneurship & organizational theory
Strategy & innovation
DOI :
10.1108/IJMPB-12-2024-0330
Author, co-author :
Mroz, Kamil Dominik ;  Université de Liège - ULiège > HEC Liège Research
Lisein, Olivier ;  Université de Liège - ULiège > HEC Liège : UER > UER Management: Gestion du changement, innovation et intrapreneuriat
Language :
English
Title :
Research Evolution on Project Management in the Pharmaceutical Sector: a Systematic Literature Review
Publication date :
In press
Journal title :
International Journal of Managing Projects in Business
ISSN :
1753-8378
eISSN :
1753-8386
Publisher :
Emerald, Bingley, United Kingdom
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 16 February 2026

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