adipose tissue; herbal medicines; phytotherapy; weight loss; Pharmacology; Complementary and Alternative Medicine
Abstract :
[en] Tynanthus fasciculatus (Vell.) Miers (Bignoniaceae) is a plant used in traditional medicine in southeastern Brazil, with aphrodisiac, antiparasitic, and tonic effects. Its extracts have a range of categories of active compounds identified, but their effects are scarcely reported in the scientific literature. We described, for the first time, the effects of T. fasciculatus infusion on body weight and adipose tissue depot weight in a Swiss mouse model. All studied doses (100, 200, and 300 mg/kg) caused a significant reduction in the weight of the interscapular brown adipose tissue and the epididymal white adipose tissue depots. The doses of 100 and 200 mg were also effective in controlling body weight gain. The infusion of T. fasciculatus was efficient in reducing adiposity and controlling weight gain.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Maia Ladeira, Luiz Carlos ; Université de Liège - ULiège > Département d'aérospatiale et mécanique > Génie biomécanique ; Université de Liège - ULiège > GIGA > GIGA Molecular & Computational Biology - Biomechanics & Computationel Tissues Engineering
Damasceno, Eduardo Medeiros ; Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Brazil
de Melo, Aline Leão de Andrade Bandeira ; Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Brazil
da Silva, Janaina ; Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Brazil
Maldonado, Izabel Regina Dos Santos Costa ; Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Brazil
da Matta, Sérgio Luis Pinto ; Departamento de Biologia Geral, Universidade Federal de Viçosa, Viçosa, Brazil
Language :
English
Title :
Anti-adiposity effect of cipó-cravo (Tynanthus fasciculatus), a vine from the Brazilian Atlantic Forest
The authors are thankful to Enedina Sacramento for English proofreading and \u201CCoordena\u00E7\u00E3o de Aperfei\u00E7oamento de Pessoal de N\u00EDvel Superior\u201D (CAPES) for the L.C.M.Ladeira scholarship (Proc. Nr. 88882.436984/2019-01).
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