ARIA; Artificial intelligence; Asthma; Evidence-based medicine; Person-centered care; Rhinitis; mHealth; Humans; Critical Pathways; Practice Guidelines as Topic; Patient-Centered Care; Asthma/therapy; Artificial Intelligence; Rhinitis, Allergic/therapy; Telemedicine; Rhinitis, Allergic; Immunology and Allergy
Abstract :
[en] The traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients' resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people's values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.1 It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Bousquet, Jean ; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany, ARIA, Montpellier, France. Electronic address: jean.bousquet@orange.fr
Schünemann, Holger J; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany, Department of Health Research Methods, Evidence, and Impact & Department of Medicine, McMaster University, Hamilton, ON, Canada, Department of Biomedical Science, Humanitas University, Pieve Emanuele, Milan, Italy
Sousa-Pinto, Bernardo; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Zuberbier, Torsten; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany, Department of Health Research Methods, Evidence, and Impact & Department of Medicine, McMaster University, Hamilton, ON, Canada
Togias, Alkis; Division of Allergy, Immunology, and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Md
Samolinski, Boleslaw; Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Bedbrook, Anna; ARIA, Montpellier, France
Czarlewski, Wienczyslawa; ARIA, Montpellier, France, Medical Consulting Czarlewski, Levallois, France
Hofmann-Apitius, Martin; Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Bonn, Germany
Litynska, Justyna; Evidence Prime, Kracow, Poland, Gynecological and Obstetrician Polyclinic, District Hospital, Białystok, Poland
Vieira, Rafael José; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Anto, Josep M; ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain, Department of Experimental Sciences, Universitat Pompeu Fabra (UPF), Barcelona, Spain, Department of Epidemiology & Public Health, CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
Fonseca, Joao A; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Brozek, Jan; Department of Health Research Methods, Evidence, and Impact & Department of Medicine, McMaster University, Hamilton, ON, Canada
Bognanni, Antonio; Department of Health Research Methods, Evidence, and Impact & Department of Medicine, Evidence in Allergy group, McMaster University, Hamilton, ON, Canada
Brussino, Luisa; Department of Medical Sciences, University of Torino, Torino, Italy, Allergy and Clinical Immunology Unit, Mauriziano Hospital, Torino, Italy
Canonica, G Walter; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy, Asthma & Allergy Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Cherrez-Ojeda, Ivan; Research Center 'Respiralab', Universidad Espíritu Santo, Samborondón, Ecuador, Department of Allergology & Pulmonology, Respiralab Research Group, Guayaquil, Guayas, Ecuador
Cruz, Alvaro A; Fundaçao ProAR, Federal University of Bahia and GARD/WHO Planning Group, Salvador, Bahia, Brazil
Vecillas, Leticia de Las; Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain
Dykewicz, Mark; Section of Allergy and Immunology, Saint Louis University School of Medicine, Saint Louis, Mo
Gemicioglu, Bilun; Department of Pulmonary Diseases, and Institute of Pulmonology & Tuberculosis, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
Giovannini, Mattia; Department of Health Sciences, University of Florence, Florence, Italy, Allergy Unit, Meyer Children's Hospital IRCCS, Florence, Italy
Haahtela, Tari; Skin and Allergy Hospital, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland
Jacobs, Marc; Department of Bioinformatics, Fraunhofer Institute for Algorithms and Scientific Computing (SCAI), Bonn, Germany
Klimek, Ludger; Department of Otolaryngology, Head & Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany, Center for Rhinology and Allergology, Allergology & Rhinology Department, Wiesbaden, Germany
Kvedariene, Violeta; Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Institute of Biomedical Sciences, Department of Pathology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Larenas-Linnemann, Desiree E; Center of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico
Louis, Gilles ; Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie
Lourenço, Olga; Faculty of Health Sciences and CICS-UBI, Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
Leemann, Lucas; Department of Political Science, University of Zürich, Zürich, Switerland
Morais-Almeida, Mario; Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal
Neves, Ana Luisa; Global Digital Health Unit, Department of Primary Care and Public Health, Imperial College, London, United Kingdom
Nadeau, Kari C; Department of Environmental Health, Harvard TH Chan School of Public Health and Department of Medicine, Division of Allergy and Inflammation, Beth Israel Deaconess Hospital, Boston, Mass
Nowak, Artur; Evidence Prime, Kracow, Poland, Gynecological and Obstetrician Polyclinic, District Hospital, Białystok, Poland
Palamarchuk, Yuliia; Finnish Meteorological Institute (FMI), Atmospheric Composition Research, Helsinki, Finland
Palkonen, Susanna; EFA European Federation of Allergy and Airways Diseases Patients' Associations, Brussels, Belgium
Papadopoulos, Nikolaos G; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece
Parmelli, Elena; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy, Asthma & Allergy Unit, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy
Pereira, Ana Margarida; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, PaCeIT-Patient Centered Innovation and Technologies, Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal, Allergy Unit, Instituto and Hospital CUF, Porto, Portugal
Pfaar, Oliver; Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany
Regateiro, Frederico S; Allergy and Clinical Immunology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Center for Innovative Biomedicine and Biotechnology (CIBB), Faculty of Medicine, University of Coimbra, Coimbra, Portugal, Institute of Immunology, Faculty of Medicine, University of Coimbra, Coimbra, Portugal, UBIAir-Clinical & Experimental Lung Centre and CICS-UBI Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
Savouré, Marine; Université de Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail)-UMR_S 1085, Rennes, France
Taborda-Barata, Luis; Department of Immunoallergology, Cova da Beira University Hospital Centre, Covilhã, Portugal, UBIAir-Clinical & Experimental Lung Centre and CICS-UBI Health Sciences Research Centre, University of Beira Interior, Covilhã, Portugal
Toppila-Salmi, Sanna K; Department of Allergy, Skin and Allergy Hospital, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland, Department of Otorhinolaryngology, University of Eastern Finland and the North Savo Wellbeing Services County, Kuopio, Finland
Torres, Maria J; Allergy Unit, Málaga Regional University Hospital of Málaga, Malaga University, ARADyAL, Malaga, Spain
Valiulis, Arunas; Clinic of Children's Diseases, Institute of Clinical Medicine, Medical Faculty of Vilnius University, Vilnius, Lithuania, Clinic of Asthma, Allergy, and Chronic Lung Diseases, Asthma & Allergy Department, Vilnius, Lithuania
Ventura, Maria Teresa; Allergy and Clinical Immunology, University of Bari Medical School, Bari, Italy, Institute of Sciences of Food Production, National Research Council (ISPA-CNR), Bari, Italy
Williams, Sian; International Primary Care Respiratory Group IPCRG, Edinburgh, United Kingdom
Yepes-Nuñez, Juan J; School of Medicine, Universidad de los Andes, Bogotá, DC, Colombia, Pulmonology Service, Internal Medicine Section, Fundación Santa Fe de Bogotá, University Hospital, Bogotá, DC, Colombia
Yorgancioglu, Arzu; Department of Pulmonary Diseases, Celal Bayar University, Faculty of Medicine, Manisa, Turkey
Zhang, Luo; Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital and Beijing Institute of Otolaryngology, Beijing, China
Zuberbier, Jaron; Department of Otorhinolaryngology, Charité-Universitätsmedizin Berlin, Berlin, Germany
Abdul Latiff, Amir Hamzah; Allergy & Immunology Centre, Pantai Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
Abdullah, Baharudin; Department of Otorhinolaryngology-Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Agache, Ioana; Faculty of Medicine, Transylvania University, Brasov, Romania
Al-Ahmad, Mona; Microbiology Department, College of Medicine, Kuwait University, Kuwait City, Kuwait
Al-Nesf, Maryam Ali; Adult Allergy and Immunology Division-Hamad Medical Corporation, Doha, Qatar
Al Shaikh, Nada A; Otolaryngology Head & Neck Surgery Department, Mouwasat Hospital, Dammam, Saudi Arabia
Amaral, Rita; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal, Department of Cardiovascular and Respiratory Sciences, Porto Health School, Polytechnic Institute of Porto, Porto, Portugal, Department of Women's and Children's Health, Paediatric Research, Uppsala University, Uppsala, Sweden
Ansotegui, Ignacio J; Department of Allergy and Immunology, Hospital Quironsalud Bizkaia, Bilbao, Spain
Asllani, Julijana; Department of Internal Medicine, University of Medicine, Tirana, Albania
Balotro-Torres, Maria Cristina; Section of Allergy, Asthma and Immunology, University of Santo Tomas Hospital, Manila, Philippines
Bergmann, Karl-Christian; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany
Bernstein, Jonathan A; Division of Immunology, Allergy and Rheumatology, Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio
Bindslev-Jensen, Carsten; Department of Dermatology and Allergy Center, Odense Research Centre for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark
Blaiss, Michael S; Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, Ga
Bonaglia, Cristina; Institute "Bona Sforza", University for Linguistic Mediators, Bari, Italy
Bonini, Matteo; Department of Cardiovascular and Respiratory Sciences, Universita Cattolica del Sacro Cuore, Rome, Italy, Department of Neurological, ENT and Thoracic Sciences, Fondazione Policlinico Universitario A Gemelli-IRCCS, Rome, Italy, National Heart and Lung Institute (NHLI), Imperial College London, London, United Kingdom
Bossé, Isabelle; Allergist, Department of Allergy, La Rochelle, France
Braido, Fulvio; Respiratory Clinic, Department of Internal Medicine, University of Genoa, Genoa, Italy, Respiratory & Allergy Clinic, IRCCS Ospedale Policlinico San Martino, Genoa, Italy
Caballero-Fonseca, Fernan; Centro Medico Docente La Trinidad, Allergology & Immunolgy Department, Caracas, Venezuela
Camargos, Paulo; Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil
Carreiro-Martins, Pedro; NOVA Medical School/Comprehensive Health Research Centre (CHRC), Lisbon, Portugal, Serviço de Imunoalergologia, Centro Hospitalar Universitário de Lisboa Central/ULS São José, Lisbon, Portugal
Casale, Thomas; Division of Allergy/Immunology, University of South Florida, Tampa, Fla
Castillo-Vizuete, José-Antonio; Department of Respiratory Medicine, Hospital Universitari Dexeus, Barcelona, Spain, The Group of Rhinitis, Rhinosinusitis and Nasal Polyps, Area of Asthma, SEPAR, Barcelona, Spain
Cecchi, Lorenzo; SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy
Teixeira, Maria do Ceu; Dr Agostinho Neto University hospital, Epidemiology Department, Praia, Cabo Verde, Immunology, Cabo Verde University, Faculty of Medicine, Praia, Cabo Verde
Chang, Yoon-Seok; Division of Allergy and Clinical Immunology, Seoul National University Bundang Hospital, Seoul National University, College of Medicine, Seoul, Republic of Korea
Loureiro, Claudia Chaves; Department of Pneumology, Coimbra University Hospital, Faculty of Medicine, Coimbra, Portugal, Coimbra Institute for Clinical and Biomedical Research, CIBB, Coimbra, Portugal
Christoff, George; Faculty of Public Health, Sofia Medical University, Sofia, Bulgaria
Ciprandi, Giorgio; Casa di Cura Villa Montallegro, Allergology Department, Genova, Italy
Cirule, Ieva; Latvian Association of Allergists, University Children Hospital, Riga, Latvia
Correia-de-Sousa, Jaime; Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal
Costa, Elisio M; CINTESIS@RISE, Biochemistry Lab, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing, University of Porto, Porto, Portugal
Cvetkovski, Biljana; Woolcock Institute of Medical Research, Quality Use of Respiratory Medicine, Sydney, NSW, Australia
de Vries, Govert; Peercode BV, Geldermalsen, the Netherlands
Del Giacco, Stefano; Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology, University Hospital "Duilio Casula", University of Cagliari, Cagliari, Italy
Devillier, Philippe; VIM Suresnes, UMR 0892, Pôle des Maladies des Voies Respiratoires, Hôpital Foch, Université Paris-Saclay, Suresnes, France
Dokic, Dejan; Medical Faculty Skopje, University Clinic of Pulmology and Allergy, Skopje, Republic of Macedonia
Douagui, Habib; Service de Pneumo-Allergologie, Centre Hospitalo-Universitaire de Béni-Messous, Algiers, Algeria
Durham, Stephen R; Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London, United Kingdom
Enecilla, Maria Lourdes; St Luke's Medical Center, ENT Department, Quezon City, Philippines
Fiocchi, Alessandro; Allergy, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy
Fokkens, Wytske J; Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC, Amsterdam, the Netherlands
Fontaine, Jean-François; CHU de Reims, Service des Maladies Respiratoires et Allergiques, Reims, France
Gawlik, Radoslaw; Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia in Katowice, Katowice, Poland
Gereda, Jose E; Clínica Ricardo Palma, Allergy & Immunology Department, Lima, Peru
Gil-Mata, Sara; MEDCIDS-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal, CINTESIS@RISE-Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Giuliano, Antonio F M; Department of Internal Medicine 'A. Murri' and Unit of Geriatric Immunoallergology, University of Bari Medical School, Bari, Italy
Gotua, Maia; Center of Allergy and Immunology, David Tvildiani Medical University, Tbilisi, Georgia
Gradauskiene, Brigita; Department of Immunology and Allergology, Lithuanian University of Health Sciences, Kaunas, Lithuania
Guzman, Maria Antonieta; Immunology and Allergy Division, Clinical Hospital, University of Chile, Santiago, Chile
Hossny, Elham; Pediatric Allergy, Immunology and Rheumatology Unit, Children's Hospital, Ain Shams University, Cairo, Egypt
Hrubiško, Martin; Department of Clinical Immunology and Allergy, Oncology Institute of St Elisabeth, Bratislava, Slovakia
Iinuma, Tomohisa; Department of Otorhinolaryngology, Chiba University, Chiba, Japan
Irani, Carla; Department of Internal Medicine and Infectious Diseases, St Joseph University, Hotel Dieu de France Hospital, Beirut, Lebanon
Ispayeva, Zhanat; Department of Allergology and Clinical Immunology, Kazakhstan Association of Allergology and Clinical Immunology, Kazakh National Medical University, Almaty, Kazakhstan
Ivancevich, Juan Carlos; Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina
Jartti, Tuomas; Research Unit of Clinical Medicine, University of Oulu, Oulu, Finland, Department of Pediatrics and Adolescent Medicine, University of Turku, Turku University Hospital, Turku, Finland
Jeseňák, Miloš; Department of Pulmonology and Phthisiology, Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Bratislava, Slovakia, Institute of Clinical Immunology and Allergology, Jessenius Faculty of Medicine in Martin, Comenius University, Bratislava, Slovakia
Julge, Kaja; Institute of Clinical Medicine, Children's Clinic, Tartu University, Tartu, Estonia
Jutel, Marek; Department of Clinical Immunology, Wrocław Medical University, Wroclaw, Poland, ALL-MED Medical Research Institute, Department of Clinical Immunology, Wroclaw, Poland
Kaidashev, Igor; Poltava State Medical University, Immunology & Allergology Department, Poltava, Ukraine
Bennoor, Kazi S; Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh
Khaltaev, Nicolai; Global NCD Platform, Geneva, Switzerland
Kirenga, Bruce; Makerere University Lung Institute, Pulmonology Medicine Department, Kampala, Uganda
Kraxner, Helga; Department of Otorhinolaryngology, Head and Neck Surgery, Semmelweis University, Budapest, Hungary
Kull, Inger; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden, Sach's Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden
Kulus, Marek; Department of Pediatric Respiratory Diseases and Allergology, Medical University of Warsaw, Warsaw, Poland
Kuna, Piotr; Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland
Kupczyk, Maciej; Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland
Kurchenko, Andriy; Department of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine
La Grutta, Stefania; Institute of Translational Pharmacology (IFT)-National Research Council (CNR), Palermo, Italy
Miculinic, Neven; Croatian Pulmonary Society, Clinical Center for Pulmonary Diseases, Zagreb, Croatia
Lee, Sang Min; Dankook University Hospital, ENT Department, Cheonan, Republic of Korea
Le Thi Tuyet, Lan; Asthma, COPD Outpatient Care Unit, University Medical Center, Hô-Chi-Minh City, Vietnam
Lkhagvaa, Battur; Mongolian National University of Medical Sciences, Health Department, Ulan Bator, Mongolia
Louis, Renaud ; Université de Liège - ULiège > Département des sciences cliniques > Pneumologie - Allergologie
Mahboub, Bassam; Rashid Hospital, DUBAI Health, Dubai, UAE, Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, UAE
Makela, Mika; Skin and Allergy Hospital, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland
Makris, Michael; Allergy Unit "D Kalogeromitros", 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens, "Attikon" University Hospital, Athens, Greece
Maurer, Marcus; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany
Melén, Eric; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden, Sach's Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden
Milenkovic, Branislava; Clinic for Pulmonary Diseases, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Serbian Association for Asthma and COPD, Belgrade, Serbia
Mohammad, Yousser; National Center for Research in Chronic Respiratory Diseases, Collaborating with WHO-EMRO Tishreen University School of Medicine, Latakia, Syria, Al-Sham Private University, Pharmacy Department, Damascus, Syria
Moniuszko, Marcin; Department of Allergology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland
Montefort, Stephen; Department of Medicine, Faculty of Medicine and Surgery, University of Malta, Msida, MSD, Malta
Moreira, Andre; EPIUnit-Institute of Public Health, University of Porto, and Laboratory for Integrative and Translational Research in Population Health (ITR), Porto, Portugal, Serviço de Imunoalergologia, Centro Hospitalar Universitário São João, Porto, Portugal, Basic and Clinical Immunology Unit, Department of Pathology, Faculty of Medicine, University of Porto, Porto, Portugal
Moreno, Pablo; Fundaler, Buenos Aires, Argentina
Mullol, Joaquim; Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain, Clinical & Experimental Respiratory Immunoallergy, FRCB-IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain
Nadif, Rachel; Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Villejuif, France, Inserm, Équipe d'Épidémiologie respiratoire intégrative, CESP, Villejuif, France
Nakonechna, Alla; Clinical Immunology and Allergy Unit, Sheffield Teaching Hospitals, Sheffield, United Kingdom, University of Liverpool, Liverpool, United Kingdom
Navarro-Locsin, Cecilia Gretchen; Department of Otolaryngology-Head & Neck Surgery, St Luke's Medical Center, Quezon City, Philippines, Division of Surgery, Philippine Children's Medical Center, Quezon City, Philippines
Neffen, Hugo E; Center of Allergy, Immunology and Respiratory Diseases, Santa Fe, Argentina
Niedoszytko, Marek; Department of Allergology, Medical University of Gdańsk, Gdansk, Poland
Nunes, Elizabete; Faculty of Medicine, Eduardo Mondlane University, Maputo, Mozambique
Nyembue, Dieudonné; ENT Department, University Hospital of Kinshasa, Kinshasa, Democratic Republic of the Congo
O'Hehir, Robyn; Allergy, Asthma and Clinical Immunology, Alfred Health and Department of Immunology, Central Clinical School, Monash University, Melbourne, VIC, Australia
Ollert, Markus; Department of Infection and Immunity, Luxembourg Institute of Health, Esch-sur-Alzette, Luxembourg, Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark
Ohta, Ken; Japan Antituberculosis Association (JATA), Fukujuji Hospital, Tokyo, Japan
Okamoto, Yoshitaka; Chiba Rosai Hospital, ENT Department, Chiba, Japan, Chiba University Hospital, Department of Otolaryngology, Head and Neck Surgery, Chiba, Japan
Okubo, Kimihiro; Deparment of Otolaryngology, Nippon Medical School, Tokyo, Japan
Olze, Heidi; Department of Otorhinolaryngology, Charité-Universitätsmedizin Berlin, Berlin, Germany
Padukudru, Mahesh Anand; Department of Respiratory Medicine, JSS Medical College, JSSAHER Mysuru, Karnataka, India
Palomares, Oscar; Department of Biochemistry and Molecular Biology, School of Chemistry, Complutense University of Madrid, Madrid, Spain
Pali-Schöll, Isabella; Institute of Pathophysiology and Allergy Research, Medical University Vienna, Vienna, Austria, Interuniversity Messerli Research Institute of the University of Veterinary Medicine and Medical University Vienna, Vienna, Austria
Panzner, Petr; Department of Immunology and Allergology, Faculty of Medicine in Pilsen, Charles University, Prague, Czech Republic
Palosuo, Kati; Department of Allergology, University of Helsinki and Hospital for Skin and Allergic Diseases, Helsinki, Finland
Park, Hae S; Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Republic of Korea
Passalacqua, Giovanni; Allergy and Respiratory Diseases, IRCCS Policlinico San Martino, University of Genoa, Genoa, Italy
Patella, Vincenzo; Division of Allergy and Clinical Immunology, Department of Medicine, "Santa Maria della Speranza" Hospital, Battipaglia, Salerno, Italy, Agency of Health ASL, Division of Allergy and Clinical Immunology, Department of Medicine, Salerno, Italy, Postgraduate Programme in Allergy and Clinical Immunology, University of Naples Federico II, Naples, Italy
Pawankar, Ruby; Department of Pediatrics, Nippon Medical School, Tokyo, Japan
Pétré, Benoît ; Université de Liège - ULiège > Département des sciences de la santé publique > Education thérapeutique du patient au service des soins intégrés
Pitsios, Constantinos; Medical School, University of Cyprus, Nicosia, Cyprus
Plavec, Davor; Prima Nova, Healthcare Institution, Zagreb, Croatia, Medical Faculty, University JJ Strossmayer of Osijek, Osijek, Croatia
Popov, Todor A; Clinic of Occupational Diseases, University Hospital Sveti Ivan Rilski, Sofia, Bulgaria
Puggioni, Francesca; IRCCS Humanitas Research Center, Personalized Medicine Asthma & Allergy, Rozzano, Milan, Italy
Quirce, Santiago; Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain
Raciborski, Filip; Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Ramonaité, Agné; Department of Pulmonology and Allergology, Klaipeda National Hospital, Klaipeda, Lithuania, Vilnius University Medical Faculty, Department of Political Behaviour and Institutions, Vilnius, Lithuania
Recto, Marysia; Division of Adult and Pediatric Allergy and Immunology, University of the Philippines - Philippines General Hospital, Manila, Philippines
Repka-Ramirez, Susana; Department of Allergy, Clinics Hospital, National University, San Lorenzo, Paraguay
Roberts, Graham; Faculty of Medicine, University of Southampton, Southampton, United Kingdom, The David Hide Asthma and Allergy Centre, St Mary's Hospital, Isle of Wight, United Kingdom, NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
Robles-Velasco, Karla; Research Center 'Respiralab', Universidad Espíritu Santo, Samborondón, Ecuador, Department of Allergology & Pulmonology, Respiralab Research Group, Guayaquil, Guayas, Ecuador
Roche, Nicolas; Pneumologie, AP-HP Centre Université de Paris Cité, Hôpital Cochin, Paris, France, UMR 1016, Institut Cochin, Paris, France, Inserm, Epidemiology Department, CESP, Villejuif, France
Rodriguez-Gonzalez, Monica; Pediatric Allergy and Clinical Immunology, Hospital Espanol de Mexico, Mexico City, Mexico
Romualdez, Joel A; Faculty of Medicine & Surgery, University of Santo Tomas, Manila, Philippines
Rottem, Menachem; Division of Allergy, Asthma and Clinical Immunology, Emek Medical Center, Afula, Israel, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
Rouadi, Philip W; Department of Otolaryngology-Head and Neck Surgery, Eye and Ear University Hospital, Beirut, Lebanon, Department of Otorhinolaryngology-Head and Neck Surgery, Dar Al Shifa Hospital, Salmiya, Kuwait
Sastre, Joaquin; Allergy Service, Fundacion Jimenez Diaz, Autonoma University of Madrid, CIBERES-ISCIII, Madrid, Spain
Serpa, Faradiba S; Asthma Reference Center-School of Medicine of Santa Casa de Misericórdia of Vitória, Espírito Santo, Brazil
Sayah, Zineb; SMAIC Société Marocaine d'Allergologie et Immunologie Clinique, Rabat, Morocco
Scichilone, Nicola; PROMISE Department, University of Palermo, Palermo, Italy
Senna, Gianenrico; Asthma-Allergy Unit, University Hospital of Verona, Verona, Italy
Sisul, Juan Carlos; Clínica Sisul, Allergy & Asthma, Medical Director, CLINICA SISUL, FACAAI, SPAAI, Asuncion, Paraguay
Solé, Dirceu; Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo, Brazil
Soto-Martinez, Manuel E; Division of Respiratory Medicine, Department of Pediatrics, Hospital Nacional de Niños, Universidad de Costa Rica, San Jose, Costa Rica
Sova, Milan; Department of Respiratory Medicine and Tuberculosis, University Hospital, Brno, Czech Republic
Sozinova, Olga; Head of Laboratory of Atmospheric processes and Aerobiology, University of Latvia, Riga, Latvia
Stevanovic, Katarina; Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany
Ulrik, Charlotte Suppli; Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Copenhagen, Denmark, Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
Szylling, Anna; Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Tan, Frances M; Department of Pediatrics, Victor R Potenciano Medical Center, Mandaluyong, Philippines
Tantilipikorn, Pongsakorn; Department of Otolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Todo-Bom, Ana; Imunoalergologia, Centro Hospitalar Universitário de Coimbra, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Tomic-Spiric, Vesna; Clinic of Allergology and Immunology, University Clinical Center of Serbia, Belgrade, Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Tsaryk, Vladyslav; Department of Clinical and Laboratory Immunology, Allergology and Medical Genetics, Bogomolets National Medical University, Kyiv, Ukraine
Tsiligianni, Ioanna; International Primary Care Respiratory Group IPCRG, Aberdeen, United Kingdom, Health Planning Unit, Department of Social Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece
Urrutia-Pereira, Marilyn; Federal University of Pampa, Department of Medicine, Uruguaiana, Brazil
Rostan, Marylin Valentin; Pediatrics, Allergy & Immunology, Latín American Society of Allergy, Asthma & immunology (SLAAi), Montevideo, Uruguay
Sofiev, Mikhail; Finnish Meteorological Institute (FMI), Atmospheric Composition Research, Helsinki, Finland
Valovirta, Erkka; Department of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland
Van Eerd, Michiel; Peercode BV, Geldermalsen, the Netherlands
Van Ganse, Eric; Research on Healthcare Performance (RESHAPE), INSERM U1290, Pneumologie et Medicine Respiratoire, Groupement Hospitalier Nord, Hôpital de la Croix Rousse, Lyon, France
Vasankari, Tuula; FiLHA, Finnish Lung Health Association, Helsinki, Finland, Department of Clinical Medicine, Pulmonary Diseases and Clinical Allergology, University of Turku, Turku, Finland
Vichyanond, Pakit; Division of Allergy and Immunology, Department of Pediatrics, Siriraj Hospital, Mahidol University Faculty of Medicine, Bangkok, Thailand
Viegi, Giovanni; Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Pisa, Italy
Wallace, Dana; Nova Southeastern University, College of Allopathic Medicine, Fort Lauderdale, Fla
Wang, De Yun; Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Republic of Singapore
Waserman, Susan; Department of Medicine, Clinical Immunology and Allergy, McMaster University, Hamilton, ON, Canada
Wong, Gary; Department of Paediatrics, Prince of Wales Hospital, Hong Kong, SAR, China
Worm, Margitta; Division of Allergy and Immunology, Department of Dermatology, Allergy and Venerology, Charité Universitätsmedizin Berlin, Berlin, Germany
Yusuf, Osman M; The Allergy and Asthma Institute, Allergy & Asthma Department, Islamabad, Pakistan
Zaitoun, Fares; Clemenceau Medical Center DHCC, Lebanese-American University, Dubai, UAE
Zidarn, Mihaela; University Clinic of Respiratory and Allergic Diseases, Pulmonary & Allergy Department, Golnik, Slovenia, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
This work has received funding from ARIA (Allergic Rhinitis and its Impact of Asthma); CATALYSE (Climate Action To Advance HeaLthY Societies in Europe), the European Union\u2019s Horizon Europe research and innovation program under grant agreement no. 101057131; FRAUNHOFER Institute for Translational Medicine and Pharmacology (ITMP), Immunology and Allergology, Berlin, Germany; University of Porto, Portugal; and MASK-air, which has been supported by EU grants (Impact of air Pollution on Asthma and Rhinitis [POLLAR] project of the European Institute of Innovation and Technology Health; Structural and Development Funds, R\u00E9gion Languedoc Roussillon and Provence-Alpes-C\u00F4te d\u2019Azur; Twinning, European Innovation Partnership on Active and Healthy Ageing, DG Sant\u00E9 and DG Connect); educational grants from Mylan-Viatris, Allergologisk Laboratorium K\u00F8benhavn, GlaxoSmithKline, Novartis, Stallerg\u00E8nes-Greer, and Noucor; and funding from Breathing Together Onlus Association (Associazione Respiriamo Insieme Onlus), Italy; Esp\u00EDritu Santo University, Samborond\u00F3n, Ecuador; Finnish Anti-Tuberculosis Association Foundation and Tampere Tuberculosis Foundation; GA 2 LEN; German Allergy Society AeDA (\u00C4rzteverband Deutscher Allergologen); IPOKRaTES (International Postgraduate Organization for Knowledge transfer, Research and Teaching Excellent Students) Lithuania Fund; Polish Society of Allergology (POLSKIE TOWARZYSTWO ALLERGOLOGICZNE); and University of Li\u00E8ge, Belgium.
Bousquet, J., Anto, J.M., Bachert, C., Baiardini, I., Bosnic-Anticevich, S., Walter Canonica, G., et al. Allergic rhinitis. Nat Rev Dis Primers, 6, 2020, 95.
Zuberbier, T., Lotvall, J., Simoens, S., Subramanian, S.V., Church, M.K., Economic burden of inadequate management of allergic diseases in the European Union: a GA(2) LEN review. Allergy 69 (2014), 1275–1279.
Bousquet, J., Van Cauwenberge, P., Khaltaev, N., Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108:Suppl (2001), S147–S334.
Brozek, J.L., Bousquet, J., Baena-Cagnani, C.E., Bonini, S., Canonica, G.W., Casale, T.B., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol 126 (2010), 466–476.
Brozek, J.L., Bousquet, J., Agache, I., Agarwal, A., Bachert, C., Bosnic-Anticevich, S., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision. J Allergy Clin Immunol 140 (2017), 950–958.
Bousquet, J., Schunemann, H.J., Togias, A., Bachert, C., Erhola, M., Hellings, P.W., et al. Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol 145 (2020), 70–80.e3.
Dykewicz, M.S., Wallace, D.V., Baroody, F., Bernstein, J., Craig, T., Finegold, I., et al. Treatment of seasonal allergic rhinitis: an evidence-based focused 2017 guideline update. Ann Allergy Asthma Immunol 119 (2017), 489–511.e41.
Dykewicz, M.S., Wallace, D.V., Amrol, D.J., Baroody, F.M., Bernstein, J.A., Craig, T.J., et al. Rhinitis 2020: a practice parameter update. J Allergy Clin Immunol 146 (2020), 721–767.
US Food and Drug Administration. Real-world data (RWD) and real-world evidence (RWE) are playing an increasing role in health care decisions. https://www.fda.gov/science-research/science-and-research-special-topics/real-world-evidence. (Accessed 2 August 2022)
Bousquet, J., Addis, A., Adcock, I., Agache, I., Agusti, A., Alonso, A., et al. Integrated care pathways for airway diseases (AIRWAYS-ICPs). Eur Respir J 44 (2014), 304–323.
Bousquet, J., Barbara, C., Bateman, E., Bel, E., Bewick, M., Chavannes, N.H., et al. AIRWAYS-ICPs (European Innovation Partnership on Active and Healthy Ageing) from concept to implementation. Eur Respir J 47 (2016), 1028–1033.
Bousquet, J., Dahl, R., Khaltaev, N., Global alliance against chronic respiratory diseases. Allergy 62 (2007), 216–223.
Yorgancioglu, A., Khaltaev, N., Bousquet, J., Varghese, C., The Global Alliance Against Chronic Respiratory Diseases: journey so far and way ahead. Chin Med J (Engl) 133 (2020), 1513–1515.
Cherrez-Ojeda, I., Bousquet, J., Sarfraz, Z., Sarfraz, A., Rodriguez Gonzales, M., Bedbrook, A., et al. Exploring the role of information and communication technologies in allergic rhinitis in specialist centers: patient perspectives on usefulness, value, and impact on healthcare. Clin Transl Allergy, 14, 2024, e12325.
Bousquet, J.J., Schunemann, H.J., Togias, A., Erhola, M., Hellings, P.W., Zuberbier, T., et al. Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases. Clin Transl Allergy, 9, 2019, 44.
International Alliance of Patients’ Organizations. The global voice for patient-centred healthcare. https://www.iapo.org.uk. (Accessed 5 October 2020)
Mulley, AG Jr, The global role of health care delivery science: learning from variation to build health systems that avoid waste and harm. J Gen Intern Med 28:Suppl 3 (2013), S646–S653.
American Geriatrics Society Expert Panel on Person-Centered Care. Person-centered care: a definition and essential elements. J Am Geriatric Soc 64 (2016), 15–18.
Hakansson, E., Holmstrom, I., Kumlin, T., Kamiski, E., Same same or different? A review of reviews of person-centred and patient-centred care. Patient Educ Concel 1 (2019), 3–11.
Granstrom, E., Wannheden, C., Brommels, M., Hvitfeldt, H., Nystrom, M.E., Digital tools as promoters for person-centered care practices in chronic care? Healthcare professionals’ experiences from rheumatology care. BMC Health Serv Res, 20, 2020, 1108.
Brice, S., Almond, H., Health professional digital capabilities frameworks: a scoping review. J Multidiscip Healthc 13 (2020), 1375–1390.
Rosengren, K., Brannefors, P., Carlstrom, E., Adoption of the concept of person-centred care into discourse in Europe: a systematic literature review. J Health Organ Manag 35 (2021), 265–280.
Agarwal, A., Chen, L., Capozza, K., Roberts, A., Golden, D.B.K., Shaker, M.S., et al. Trustworthy patient-centered guidelines: insights from atopic dermatitis and a proposal for the future. J Allergy Clin Immunol Pract 10 (2022), 2875–2877.
Bousquet, J., Bedbrook, A., Czarlewski, W., Onorato, G.L., Arnavielhe, S., Laune, D., et al. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Clin Transl Allergy, 9, 2019, 16.
Bousquet, J., Fokkens, W., Burney, P., Durham, S.R., Bachert, C., Akdis, C.A., et al. Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper. Allergy 63 (2008), 842–853.
Brandt, D., Bernstein, J.A., Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis. Ann Allergy Asthma Immunol 96 (2006), 526–532.
Bernstein, J.A., Bernstein, J.S., Makol, R., Ward, S., Allergic rhinitis: a review. JAMA 331 (2024), 866–877.
Bernstein, J.A., Levin, L.S., Al-Shuik, E., Martin, V.T., Clinical characteristics of chronic rhinitis patients with high vs low irritant trigger burdens. Ann Allergy Asthma Immunol 109 (2012), 173–178.
Segboer, C., Gevorgyan, A., Avdeeva, K., Chusakul, S., Kanjanaumporn, J., Aeumjaturapat, S., et al. Intranasal corticosteroids for non-allergic rhinitis. Cochrane Database Syst Rev, 2019, 2019, CD010592.
Pang, J.C., Vasudev, M., Du, A.T., Nottoli, M.M., Dang, K., Kuan, E.C., Intranasal anticholinergics for treatment of chronic rhinitis: systematic review and meta-analysis. Laryngoscope 133 (2023), 722–731.
El Khoury, P., Abou Hamad, W., Khalaf, M.G., El Hadi, C., Assily, R., Rassi, S., et al. Ipratropium bromide nasal spray in non-allergic rhinitis: a systematic review and meta-analysis. Laryngoscope 133 (2023), 3247–3255.
Khoueir, N., Khalaf, M.G., Assily, R., Rassi, S., Hamad, W.A., Intranasal antihistamines in the treatment of idiopathic non-allergic rhinitis: a systematic review and meta-analysis. Rhinology 61 (2023), 290–296.
Banov, C.H., Lieberman, P., Vasomotor Rhinitis Study, G., Efficacy of azelastine nasal spray in the treatment of vasomotor (perennial nonallergic) rhinitis. Ann Allergy Asthma Immunol 86 (2001), 28–35.
Testera-Montes, A., Salas, M., Palomares, F., Ariza, A., Torres, M.J., Rondon, C., et al. Local respiratory allergy: from rhinitis phenotype to disease spectrum. Front Immunol, 12, 2021, 691964.
Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 63:Suppl 86 (2008), 8–160.
Members of the Workshops. ARIA in the pharmacy: management of allergic rhinitis symptoms in the pharmacy. Allergic rhinitis and its impact on asthma. Allergy 59 (2004), 373–387.
Bousquet, J., Schunemann, H.J., Samolinski, B., Demoly, P., Baena-Cagnani, C.E., Bachert, C., et al. Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. J Allergy Clin Immunol 130 (2012), 1049–1062.
Bousquet, J., Schunemann, H.J., Hellings, P.W., Arnavielhe, S., Bachert, C., Bedbrook, A., et al. MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis. J Allergy Clin Immunol 138 (2016), 367–374.e2.
Courbis, A.L., Murray, R.B., Arnavielhe, S., Caimmi, D., Bedbrook, A., Van Eerd, M., et al. Electronic clinical decision support system for allergic rhinitis management: MASK e-CDSS. Clin Exp Allergy 48 (2018), 1640–1653.
US Food and Drug Administration. Use of Real-World Evidence to Support Regulatory Decision-Making for Medical Devices. Guidance for Industry and Food and Drug Administration Staff. 2017, US Food and Drug Administration, Bethesda, MD.
Sherman, R.E., Anderson, S.A., Dal Pan, G.J., Gray, G.W., Gross, T., Hunter, N.L., et al. Real-world evidence—What is it and what can it tell us?. N Engl J Med 375 (2016), 2293–2297.
Briere, J.B., Bowrin, K., Taieb, V., Millier, A., Toumi, M., Coleman, C., Meta-analyses using real-world data to generate clinical and epidemiological evidence: a systematic literature review of existing recommendations. Curr Med Res Opin 34 (2018), 2125–2130.
Bousquet, J., Hellings, P.W., Agache, I., Bedbrook, A., Bachert, C., Bergmann, K.C., et al. ARIA 2016: care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle. Clin Transl Allergy, 6, 2016, 47.
Bousquet, J., Anto, J.M., Annesi-Maesano, I., Dedeu, T., Dupas, E., Pepin, J.L., et al. POLLAR: Impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health (EIT Health) project. Clin Transl Allergy, 8, 2018, 36.
Bousquet, J., Arnavielhe, S., Bedbrook, A., Bewick, M., Laune, D., Mathieu-Dupas, E., et al. MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence. Clin Transl Allergy, 8, 2018, 45.
Bousquet, J., Hellings, P.W., Agache, I., Amat, F., Annesi-Maesano, I., Ansotegui, I.J., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) phase 4 (2018): change management in allergic rhinitis and asthma multimorbidity using mobile technology. J Allergy Clin Immunol 143 (2019), 864–879.
Bousquet, J., Farrell, J., Illario, M., ARIA-MASK study group. Aligning the good practice MASK with the objectives of the European Innovation Partnership on Active and Healthy Ageing. Allergy Asthma Immunol Res 12 (2020), 238–258.
Bousquet, J., Toumi, M., Sousa-Pinto, B., Anto, J.M., Bedbrook, A., Czarlewski, W., et al. The Allergic Rhinitis and its Impact on Asthma (ARIA) approach of value-added medicines: as-needed treatment in allergic rhinitis. J Allergy Clin Immunol Pract 10 (2022), 2878–2888.
Bousquet, J., Anto, J.M., Haahtela, T., Jousilahti, P., Erhola, M., Basagana, X., et al. Digital transformation of health and care to sustain Planetary Health: the MASK proof-of-concept for airway diseases-POLLAR symposium under the auspices of Finland's Presidency of the EU, 2019 and MACVIA-France, Global Alliance against Chronic Respiratory Diseases (GARD, WH0) demonstration project, Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing. Clin Transl Allergy, 10, 2020, 24.
Sousa-Pinto, B., Palamarchuk, Y., Leemann, L., Jankin, S., Basagana, X., Ballester, J., et al. From MASK-air(R) and SILAM to CATALYSE (Climate Action to Advance HeaLthY Societies in Europe). J Investig Allergol Clin Immunol 34 (2024), 12–19.
Brozek, J.L., Akl, E.A., Alonso-Coello, P., Lang, D., Jaeschke, R., Williams, J.W., et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines. Part 1 of 3. An overview of the GRADE approach and grading quality of evidence about interventions. Allergy 64 (2009), 669–677.
Brozek, J.L., Akl, E.A., Compalati, E., Kreis, J., Terracciano, L., Fiocchi, A., et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines part 3 of 3. The GRADE approach to developing recommendations. Allergy 66 (2011), 588–595.
Brozek, J.L., Akl, E.A., Jaeschke, R., Lang, D.M., Bossuyt, P., Glasziou, P., et al. Grading quality of evidence and strength of recommendations in clinical practice guidelines: part 2 of 3. The GRADE approach to grading quality of evidence about diagnostic tests and strategies. Allergy 64 (2009), 1109–1116.
Brignardello-Petersen, R., Carrasco-Labra, A., Guyatt, G.H., How to interpret and use a clinical practice guideline or recommendation: users’ guides to the medical literature. JAMA 326 (2021), 1516–1523.
Bousquet, J., Lund, V.J., Van Cauwenberge, P., Bremard-Oury, C., Mounedji, N., Stevens, M.T., et al. Implementation of guidelines for seasonal allergic rhinitis: a randomized controlled trial. Allergy 58 (2003), 733–741.
Bousquet, J., Bodez, T., Gehano, P., Klossek, J.M., Liard, F., Neukirch, F., et al. Implementation of guidelines for allergic rhinitis in specialist practices. A randomized pragmatic controlled trial. Int Arch Allergy Immunol 150 (2009), 75–82.
Costa, D.J., Amouyal, M., Lambert, P., Ryan, D., Schunemann, H.J., Daures, J.P., et al. How representative are clinical study patients with allergic rhinitis in primary care?. J Allergy Clin Immunol 127 (2011), 920–926.e1.
Oyinlola, J.O., Campbell, J., Kousoulis, A.A., Is real world evidence influencing practice? A systematic review of CPRD research in NICE guidances. BMC Health Serv Res, 16, 2016, 299.
Anto, A., Sousa-Pinto, B., Czarlewski, W., Bosnic-Ancitevich, O.P.S., Klimek, L., Matricardi, P., et al. Automatic market research of mobile health apps for the self-management of allergic rhinitis. Clkin Exp Allergy 52 (2022), 1195–1207.
Bastl, K., Bastl, M., Bergmann, K.C., Berger, M., Berger, U., Translating the burden of pollen allergy into numbers using electronically generated symptom data from the patient's hayfever diary in Austria and Germany: 10-year observational study. J Med Internet Res, 22, 2020, e16767.
Giordani, P., Perna, S., Bianchi, A., Pizzulli, A., Tripodi, S., Matricardi, P.M., A study of longitudinal mobile health data through fuzzy clustering methods for functional data: the case of allergic rhinoconjunctivitis in childhood. PLoS One, 15, 2020, e0242197.
Lipp, T., Acar Sahin, A., Aggelidis, X., Arasi, S., Barbalace, A., Bourgoin, A., et al. Heterogeneity of pollen food allergy syndrome in seven Southern European countries: the @IT.2020 multicenter study. Allergy 76 (2021), 3041–3052.
Sousa-Pinto, B., Anto, A., Berger, M., Dramburg, S., Pfaar, O., Klimek, L., et al. Real-world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities. Clin Transl Allergy, 12, 2022, e12208.
Bousquet, J., Devillier, P., Anto, J.M., Bewick, M., Haahtela, T., Arnavielhe, S., et al. Daily allergic multimorbidity in rhinitis using mobile technology: a novel concept of the MASK study. Allergy 73 (2018), 1622–1631.
Sousa-Pinto, B., Sa-Sousa, A., Vieira, R.J., Amaral, R., Klimek, L., Czarlewski, W., et al. Behavioural patterns in allergic rhinitis medication in Europe: a study using MASK-air((R)) real-world data. Allergy 77 (2022), 2699–2711.
Sousa-Pinto, B., Schünemann, H., Sá-Sousa, A., Vieira, R., Amaral, R., Anto, J., et al. Consistent trajectories of rhinitis control and treatment in 16,177 weeks: the MASK-air® longitudinal study. Allergy 78 (2023), 968–983.
Sousa-Pinto, B., Schunemann, H.J., Sa-Sousa, A., Vieira, R.J., Amaral, R., Anto, J.M., et al. Comparison of rhinitis treatments using MASK-air(R) data and considering the Minimal Important Difference. Allergy 77 (2022), 3002–3014.
Sousa-Pinto, B., Jacome, C., Pereira, A.M., Regateiro, F.S., Almeida, R., Czarlewski, W., et al. Development and validation of an electronic daily control score for asthma (e-DASTHMA): a real-world direct patient data study. Lancet Digit Health 5 (2023), e227–e238.
Bedard, A., Basagana, X., Anto, J.M., Garcia-Aymerich, J., Devillier, P., Arnavielhe, S., et al. Mobile technology offers novel insights into the control and treatment of allergic rhinitis: the MASK study. J Allergy Clin Immunol 144 (2019), 135–143.e6.
Bousquet, J., Devillier, P., Arnavielhe, S., Bedbrook, A., Alexis-Alexandre, G., van Eerd, M., et al. Treatment of allergic rhinitis using mobile technology with real-world data: the MASK observational pilot study. Allergy 73 (2018), 1763–1774.
Menditto, E., Costa, E., Midao, L., Bosnic-Anticevich, S., Novellino, E., Bialek, S., et al. Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study. Clin Exp Allergy 49 (2019), 442–460.
Sousa-Pinto, B., Schunemann, H.J., Sa-Sousa, A., Vieira, R.J., Amaral, R., Anto, J.M., et al. Consistent trajectories of rhinitis control and treatment in 16,177 weeks: the MASK-air(R) longitudinal study. Allergy 78 (2023), 968–983.
Vandenplas, O., Suarthana, E., Rifflart, C., Lemiere, C., Le Moual, N., Bousquet, J., The impact of work-related rhinitis on quality of life and work productivity: a general workforce-based survey. J Allergy Clin Immunol Pract 8 (2020), 1583–1591.e5.
Bousquet, J., Schroder-Bernhardi, D., Bachert, C., Canonica, G.W., Cardona, V., Costa, E.M., et al. Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms. Clin Exp Allergy 51 (2021), 1033–1045.
Bousquet, J., Bachert, C., Canonica, G.W., Casale, T.B., Cruz, A.A., Lockey, R.J., et al. Unmet needs in severe chronic upper airway disease (SCUAD). J Allergy Clin Immunol 124 (2009), 428–433.
Bousquet, J., Chanal, I., Alquie, M.C., Charpin, D., Didier, A., Germouty, J., et al. Prevention of pollen rhinitis symptoms: comparison of fluticasone propionate aqueous nasal spray and disodium cromoglycate aqueous nasal spray. A multicenter, double-blind, double-dummy, parallel-group study. Allergy 48 (1993), 327–333.
Bousquet, J., Murray, R., Price, D., Somekh, D., Munter, L., Phillips, J., et al. The allergic allergist behaves like a patient. Ann Allergy Asthma Immunol 121 (2018), 741–742.
Miller, T.A., Health literacy and adherence to medical treatment in chronic and acute illness: a meta-analysis. Patient Educ Couns 99 (2016), 1079–1086.
Batterham, R.W., Hawkins, M., Collins, P.A., Buchbinder, R., Osborne, R.H., Health literacy: applying current concepts to improve health services and reduce health inequalities. Public Health 132 (2016), 3–12.
Agency for Healthcare Research and Quality (AHRQ). The CAHPS ambulatory care improvement guide. Practical strategies for improving patient experience. Strategy 61: shared decision making. https://www.ahrq.gov/cahps/quality-improvement/improvement-guide/6-strategies-for-improving/communication/strategy6i-shared-decisionmaking.html. (Accessed 1 July 2017)
Barry, M.J., Edgman-Levitan, S., Shared decision making–pinnacle of patient-centered care. N Engl J Med 366 (2012), 780–781.
Conard, S., Best practices in digital health literacy. Int J Cardiol 292 (2019), 277–279.
Licari, A., Ferrante, G., Marseglia, Md GL., Corsello, Md G., La Grutta, S., What is the impact of innovative electronic health interventions in improving treatment adherence in asthma? The pediatric perspective. J Allergy Clin Immunol Pract 7 (2019), 2574–2579.
Brozek, J., Borowiack, E., Sadowska, E., Nowak, A., Sousa-Pinto, B., Vieira, R.J., et al. Patients’ values and preferences for health states in allergic rhinitis—an artificial intelligence supported systematic review. Allergy 79 (2024), 1812–1830.
Campbell, H., Hotchkiss, R., Bradshaw, N., Porteous, M., Integrated care pathways. BMJ 316 (1998), 133–137.
Hujala, A., Taskinen, H., Rissanen, S. In, Richardson, E., van Ginneken, E., (eds.) How to support integration to promote care for people with multimorbidity in Europe? European Observatory Policy Briefs, 2017, European Observatory on Health Systems and Policies, Copenhagen, Denmark.
Palmer, K., Marengoni, A., Forjaz, M.J., Jureviciene, E., Laatikainen, T., Mammarella, F., et al. Multimorbidity care model: recommendations from the consensus meeting of the Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS). Health Policy 122 (2018), 4–11.
Chisholm-Burns, M.A., Kim Lee, J., Spivey, C.A., Slack, M., Herrier, R.N., Hall-Lipsy, E., et al. US pharmacists' effect as team members on patient care: systematic review and meta-analyses. Med Care 48 (2010), 923–933.
Lee, J.K., Slack, M.K., Martin, J., Ehrman, C., Chisholm-Burns, M., Geriatric patient care by U.S. pharmacists in healthcare teams: systematic review and meta-analyses. J Am Geriatr Soc 61 (2013), 1119–1127.
Skypala, I.J., de Jong, N.W., Angier, E., Gardner, J., Kull, I., Ryan, D., et al. Promoting and achieving excellence in the delivery of Integrated Allergy Care: the European Academy of Allergy & Clinical Immunology competencies for allied health professionals working in allergy. Clin Transl Allergy, 8, 2018, 31.
Bousquet, J., Pham-Thi, N., Bedbrook, A., Agache, I., Annesi-Maesano, I., Ansotegui, I., et al. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 2). J Thorac Dis 11 (2019), 4072–4084.
Bousquet, J., Pham-Thi, N., Bedbrook, A., Agache, I., Annesi-Maesano, I., Ansotegui, I., et al. Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases-Meeting Report (Part 1). J Thorac Dis 11 (2019), 3633–3642.
Bosnic-Anticevich, S., Costa, E., Menditto, E., Lourenco, O., Novellino, E., Bialek, S., et al. ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”: AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Sante) POLLAR (Impact of Air POLLution on Asthma and Rhinitis) GARD Demonstration project. Allergy 74 (2019), 1219–1236.
Lourenco, O., Bosnic-Anticevich, S., Costa, E., Fonseca, J.A., Menditto, E., Cvetkovski, B., et al. Managing allergic rhinitis in the pharmacy: an ARIA guide for implementation in practice. Pharmacy (Basel), 8, 2020, 85.
Lourenco, O., Cvetkovski, B., Kritikos, V., House, R., Scheire, S., Costa, E.M., et al. Management of allergic rhinitis symptoms in the pharmacy pocket guide 2022. Clin Transl Allergy, 12, 2022, e12183.
Bousquet, J., Pfaar, O., Togias, A., Schunemann, H.J., Ansotegui, I., Papadopoulos, N.G., et al. 2019 ARIA care pathways for allergen immunotherapy. Allergy 74 (2019), 2087–2102.
Bousquet, J., Pfaar, O., Agache, I., Bedbrook, A., Akdis, C.A., Canonica, G.W., et al. ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy. Clin Transl Allergy, 11, 2021, e12014.
Bedard, A., Sofiev, M., Arnavielhe, S., Anto, J.M., Garcia-Aymerich, J., Thibaudon, M., et al. Interactions between air pollution and pollen season for rhinitis using mobile technology: a MASK-POLLAR study. J Allergy Clin Immunol Pract 8 (2020), 1063–1073.e4.
Sofiev, M., Palamarchuk, Y., Bedard, A., Basagana, X., Anto, J.M., Kouznetsov, R., et al. A demonstration project of Global Alliance against Chronic Respiratory Diseases: prediction of interactions between air pollution and allergen exposure-the Mobile Airways Sentinel NetworK-Impact of air POLLution on Asthma and Rhinitis approach. Chin Med J (Engl) 133 (2020), 1561–1567.
Satyaraj, E., Wedner, H.J., Bousquet, J., Keep the cat, change the care pathway: a transformational approach to managing Fel d 1, the major cat allergen. Allergy 74:Suppl 107 (2019), 5–17.
Burte, E., Leynaert, B., Bono, R., Brunekreef, B., Bousquet, J., Carsin, A.E., et al. Association between air pollution and rhinitis incidence in two European cohorts. Environ Int 115 (2018), 257–266.
Burte, E., Leynaert, B., Marcon, A., Bousquet, J., Benmerad, M., Bono, R., et al. Long-term air pollution exposure is associated with increased severity of rhinitis in 2 European cohorts. J Allergy Clin Immunol 145 (2020), 834–842.e6.
Maio, S., Fasola, S., Marcon, A., Angino, A., Baldacci, S., Bilo, M.B., et al. Relationship of long-term air pollution exposure with asthma and rhinitis in Italy: an innovative multipollutant approach. Environ Res, 224, 2023, 115455.
Nadeau, K.C., Agache, I., Jutel, M., Annesi Maesano, I., Akdis, M., Sampath, V., et al. Climate change: a call to action for the United Nations. Allergy 77 (2022), 1087–1090.
Haahtela, T., von Hertzen, L., Anto, J.M., Bai, C., Baigenzhin, A., Bateman, E.D., et al. Helsinki by nature: the Nature Step to Respiratory Health. Clin Transl Allergy, 9, 2019, 57.
Halonen, J.I., Erhola, M., Furman, E., Haahtela, T., Jousilahti, P., Barouki, R., et al. A call for urgent action to safeguard our planet and our health in line with the Helsinki Declaration. Environ Res, 193, 2021, 110600.
Neumann, I., Anto, J.M., Bousquet, J., Schunemann, H.J., The impact of climate change on health needs structured evidence assessment and an evidence to action framework to make decisions: a proposal to adopt the GRADE approach. J Clin Epidemiol 157 (2023), 146–153.
Halonen, J.I., Erhola, M., Furman, E., Haahtela, T., Jousilahti, P., Barouki, R., et al. The Helsinki Declaration 2020: Europe that protects. Lancet Planet Health 4 (2020), e503–e505.
Whitmee, S., Haines, A., Beyrer, C., Boltz, F., Capon, A.G., de Souza Dias, B.F., et al. Safeguarding human health in the Anthropocene epoch: report of the Rockefeller Foundation-Lancet Commission on planetary health. Lancet 386 (2015), 1973–2028.
Anto, J., Human health and the health of Planet Earth go together. J Intern Med 295 (2024), 695–706.
UNEP (United Nations Environment Programme). WCMC (World Conservation Monitoring Centre). A glossary of definitions, Nature loss definition | Biodiversity A-Z. https://www.unep.org/facts-about-nature-crisis. (Accessed 7 December 2022)
Anto, J.M., Bousquet, J., Akdis, M., Auffray, C., Keil, T., Momas, I., et al. Mechanisms of the Development of Allergy (MeDALL): introducing novel concepts in allergy phenotypes. J Allergy Clin Immunol 139 (2017), 388–399.
Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon-Thomsen, A., Keil, T., et al. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy 66 (2011), 596–604.
Bousquet, J., Melen, E., Haahtela, T., Koppelman, G.H., Togias, A., Valenta, R., et al. Rhinitis associated with asthma is distinct from rhinitis alone: the ARIA-MeDALL hypothesis. Allergy 78 (2023), 1169–1203.
Leynaert, B., Neukirch, C., Kony, S., Guenegou, A., Bousquet, J., Aubier, M., et al. Association between asthma and rhinitis according to atopic sensitization in a population-based study. J Allergy Clin Immunol 113 (2004), 86–93.
Cruz, A.A., Popov, T., Pawankar, R., Annesi-Maesano, I., Fokkens, W., Kemp, J., et al. Common characteristics of upper and lower airways in rhinitis and asthma: ARIA update, in collaboration with GA(2)LEN. Allergy 62:Suppl 84 (2007), 1–41.
Bousquet, J., Anto, J.M., Wickman, M., Keil, T., Valenta, R., Haahtela, T., et al. Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis. Allergy 70 (2015), 1062–1078.
Bousquet, J., Anto, J.M., Just, J., Keil, T., Siroux, V., Wickman, M., The multimorbid polysensitized phenotype is associated with the severity of allergic diseases. J Allergy Clin Immunol 139 (2017), 1407–1408.
Pinart, M., Benet, M., Annesi-Maesano, I., von Berg, A., Berdel, D., Carlsen, K.C., et al. Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study. Lancet Respir Med 2 (2014), 131–140.
Fasola, S., Ferrante, G., Cilluffo, G., Malizia, V., Alfano, P., Montalbano, L., et al. Asthma comorbidities: frequency, risk factors, and associated burden in children and adolescents. Children (Basel), 9, 2022, 1001.
Bousquet, J., Sousa-Pinto, B., Anto, J., Amaral, R., Brussino, L., Canonica, G.W., et al. Identification by cluster analysis of patients with asthma and nasal symptoms using the MASK-air® mHealth app. Pulmonology 29 (2023), 292–305.
Cibella, F., Ferrante, G., Cuttitta, G., Bucchieri, S., Melis, M.R., La Grutta, S., et al. The burden of rhinitis and rhinoconjunctivitis in adolescents. Allergy Asthma Immunol Res 7 (2015), 44–50.
Malizia, V., Ferrante, G., Cilluffo, G., Gagliardo, R., Landi, M., Montalbano, L., et al. Endotyping seasonal allergic rhinitis in children: a cluster analysis. Front Med (Lausanne), 8, 2021, 806911.
Siroux, V., Ballardini, N., Soler, M., Lupinek, C., Boudier, A., Pin, I., et al. The asthma-rhinitis multimorbidity is associated with IgE polysensitization in adolescents and adults. Allergy 73 (2018), 1447–1458.
Siroux, V., Boudier, A., Nadif, R., Lupinek, C., Valenta, R., Bousquet, J., Association between asthma, rhinitis, and conjunctivitis multimorbidities with molecular IgE sensitization in adults. Allergy 74 (2019), 824–827.
Toppila-Salmi, S., Lemmetyinen, R., Chanoine, S., Karjalainen, J., Pekkanen, J., Bousquet, J., et al. Risk factors for severe adult-onset asthma: a multi-factor approach. BMC Pulm Med, 21, 2021, 214.
Amaral, R., Bousquet, J., Pereira, A.M., Araujo, L.M., Sa-Sousa, A., Jacinto, T., et al. Disentangling the heterogeneity of allergic respiratory diseases by latent class analysis reveals novel phenotypes. Allergy 74 (2019), 698–708.
Raciborski, F., Bousquet, J., Bousqet, J., Namyslowski, A., Krzych-Falta, E., Tomaszewska, A., et al. Dissociating polysensitization and multimorbidity in children and adults from a Polish general population cohort. Clin Transl Allergy, 9, 2019, 4.
Burte, E., Bousquet, J., Siroux, V., Just, J., Jacquemin, B., Nadif, R., The sensitization pattern differs according to rhinitis and asthma multimorbidity in adults: the EGEA study. Clin Exp Allergy 47 (2017), 520–529.
Savoure, M., Bousquet, J., Leynaert, B., Renuy, A., Siroux, V., Goldberg, M., et al. Rhinitis phenotypes and multimorbidities in the general population: the CONSTANCES cohort. Eur Respir J, 61, 2022, 2200943.
Lemonnier, N., Melen, E., Jiang, Y., Joly, S., Menard, C., Aguilar, D., et al. A novel whole blood gene expression signature for asthma, dermatitis, and rhinitis multimorbidity in children and adolescents. Allergy 75 (2020), 3248–3260.
Bousquet, J., Shamji, M.H., Anto, J.M., Schunemann, H.J., Canonica, G.W., Jutel, M., et al. Patient-centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA-EAACI approach. Allergy 78 (2023), 1758–1776.
Sousa-Pinto, B., Azevedo, L.F., Jutel, M., Agache, I., Canonica, G.W., Czarlewski, W., et al. Development and validation of combined symptom-medication scores for allergic rhinitis. Allergy 77 (2022), 2147–2162.
American Diabetes Association. 6. Glycemic Targets: Standards of Medical Care in Diabetes-2019. Diabetes Care 42:Suppl 1 (2019), S61–S70.
National Institute for Health and Care Excellence. Type 2 diabetes in adults: management. https://www.nice.org.uk/guidance/ng28. (Accessed 30 June 2022)
van der Leeuw, S., van der Molen, T., Dekhuijzen, P.N., Fonseca, J.A., van Gemert, F.A., Gerth van Wijk, R., et al. The minimal clinically important difference of the Control of Allergic Rhinitis and Asthma Test (CARAT): cross-cultural validation and relation with pollen counts. NPJ Prim Care Respir Med, 25, 2015, 14107.
Linhares, D.V., da Fonseca, J.A., Borrego, L.M., Matos, A., Pereira, A.M., Sa-Sousa, A., et al. Validation of control of allergic rhinitis and asthma test for children (CARATKids)—a prospective multicenter study. Pediatr Allergy Immunol 25 (2014), 173–179.
Fonseca, J.A., Nogueira-Silva, L., Morais-Almeida, M., Azevedo, L., Sa-Sousa, A., Branco-Ferreira, M., et al. Validation of a questionnaire (CARAT10) to assess rhinitis and asthma in patients with asthma. Allergy 65 (2010), 1042–1048.
Wang, Y., Chen, H., Zhu, R., Liu, G., Huang, N., Li, W., et al. Allergic Rhinitis Control Test questionnaire-driven stepwise strategy to improve allergic rhinitis control: a prospective study. Allergy 71 (2016), 1612–1619.
Nathan, R.A., Dalal, A.A., Stanford, R.H., Meltzer, E.O., Schatz, M., Derebery, J., et al. Qualitative Development of the Rhinitis Control Assessment Test (RCAT), an instrument for evaluating rhinitis symptom control. Patient 3 (2010), 91–99.
Juniper, E.F., O'Byrne, P.M., Guyatt, G.H., Ferrie, P.J., King, D.R., Development and validation of a questionnaire to measure asthma control. Eur Respir J 14 (1999), 902–907.
Schatz, M., Sorkness, C.A., Li, J.T., Marcus, P., Murray, J.J., Nathan, R.A., et al. Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allergy Clin Immunol 117 (2006), 549–556.
Sousa-Pinto, B., Vieira, R.J., Marquez-Cruz, M., Bognani, A., Gil-Mata, S., Jankin, S., et al. Artificial intelligence-supported development of health guideline questions. Ann Intern Med, 2024 In press.
Neisinger, S., Sousa Pinto, B., Ramanauskaite, A., Bousquet, J., Weller, K., Metz, M., et al. CRUSE((R))—an innovative mobile application for patient monitoring and management in chronic spontaneous urticaria. Clin Transl Allergy, 14, 2024, e12328.
Samolinski, B., Fronczak, A., Kuna, P., Akdis, C.A., Anto, J.M., Bialoszewski, A.Z., et al. Prevention and control of childhood asthma and allergy in the EU from the public health point of view: Polish Presidency of the European Union. Allergy 67 (2012), 726–731.
Valiulis, A., Bousquet, J., Veryga, A., Suprun, U., Sergeenko, D., Cebotari, S., et al. Vilnius Declaration on chronic respiratory diseases: multisectoral care pathways embedding guided self-management, mHealth and air pollution in chronic respiratory diseases. Clin Transl Allergy, 9, 2019, 7.
Bousquet, J., Samolinski, B., Kaidashev, I., Maurer, M., Roche, N., Sousa-Pinto, B., et al. UCRAID (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan. Allergy 78 (2023), 2581–2595.
Bousquet, J., Sousa-Pinto, B., Anto, J.M., Bedbrook, A., Fonseca, J.A., Zuberbier, T., et al. MASK-air: an OECD (Organisation for Economic Co-operation and Development) best practice for public health on integrated care for chronic diseases. J Allergy Clin Immunol Pract, 12, 2024, 2010 6.e7.
OECD. Integrating care to prevent and manage chronic diseases: best practices in public health. 2023, OECD, Paris.
Bousquet, J., VanCauwenberge, P., Khaltaev, N., Allergic Rhinitis and Its Impact on Asthma (ARIA)—Executive summary. Allergy 57 (2002), 841–855.
International Telecommunication Union (ITU). More than three quarters of the world's population owns a mobile phone. https://ww.itu.int./itu-d/reports./statitics/2023/10/10/ff23-mobile-phone-ownership/, 2023. (Accessed 28 April 2015)
World Health Organization. Be he@lthy be mobile: a handbook on how to implement mBreatheFreely, mHealth for COPD and asthma. https://apps.who.int/iris/handle/10665/274575. (Accessed 28 January 2017)
Bousquet, J., VanCauwenberge, P., Khaltaev, N., Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 108 (2002), S147–S334.
Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 63:Suppl 86 (2008), 8–160.
Brozek, J.L., Bousquet, J., Baena-Cagnani, C.E., Bonini, S., Canonica, G.W., Casale, T.B., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 revision. J Allergy Clin Immunol 126 (2010), 466–476.
Brozek, J.L., Bousquet, J., Agache, I., Agarwal, A., Bachert, C., Bosnic-Anticevich, S., et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. J Allergy Clin Immunol 140 (2017), 950–958.
Bousquet, J., Schunemann, H.J., Togias, A., Bachert, C., Erhola, M., Hellings, P.W., et al. Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. J Allergy Clin Immunol 145 (2020), 70–80.e3.
Bousquet, J., Dahl, R., Khaltaev, N., Global alliance against chronic respiratory diseases. Allergy 62 (2007), 216–223.
World Health Organization and International Telecommunication Union. Mobile health for asthma and chronic obstructive respiratory disease (mBreatheFreely). 2017 https://www.who.int/publications/i/item/9789241514002. (Accessed 2 January 2018)
Bousquet, J., Burney, P.G., Zuberbier, T., Cauwenberge, P.V., Akdis, C.A., Bindslev-Jensen, C., et al. GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma ‘epidemic’. Allergy 64 (2009), 969–977.
Bousquet, J., Anto, J., Auffray, C., Akdis, M., Cambon-Thomsen, A., Keil, T., et al. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy 66 (2011), 596–604.
Anto, J.M., Bousquet, J., Akdis, M., Auffray, C., Keil, T., Momas, I., et al. Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes. J Allergy Clin Immunol 139 (2017), 388–399.
Bousquet, J., Illario, M., Farrell, J., Batey, N., Carriazo, A.M., Malva, J., et al. The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing. Transl Med UniSa 19 (2019), 66–81.
Bousquet, J., Mercier, J., Avignon, A., Camuzat, T., Abadie, F., Strategic Intelligence Monitor on Personal Health Systems Phase 3 (SIMPHS3) MACVIA-LR (France) Case Study Report. 2015 https://publications.jrc.ec.europa.eu/repository/handle/JRC94487. (Accessed 15 July 2024)
Bousquet, J., Arnavielhe, S., Bedbrook, A., Fonseca, J., Morais Almeida, M., Todo Bom, A., et al. The Allergic Rhinitis and its Impact on Asthma (ARIA) score of allergic rhinitis using mobile technology correlates with quality of life: the MASK study. Allergy 73 (2018), 505–510.
Bousquet, J., Agache, I., Aliberti, M.R., Angles, R., Annesi-Maesano, I., Anto, J.M., et al. Transfer of innovation on allergic rhinitis and asthma multimorbidity in the elderly (MACVIA-ARIA)—Reference Site Twinning (EIP on AHA). Allergy 73 (2017), 77–92.
Bousquet, J., Bedbrook, A., Czarlewski, W., De Carlo, G., Fonseca, J.A., Gonzalez Ballester, M.A., et al. Digital Health Europe (DHE) Twinning on severe asthma-kick-off meeting report. J Thorac Dis 13 (2021), 3215–3225.
Bousquet, J., Anto, J.M., Annesi-Maesano, I., Dedeu, T., Dupas, E., Pepin, J.L., et al. POLLAR: impact of air POLLution on Asthma and Rhinitis; a European Institute of Innovation and Technology Health (EIT Health) project. Clin Transl Allergy, 8, 2018, 36.
Sofiev, M., Palamarchuk, Y., Bedard, A., Basagana, X., Anto, J.M., Kouznetsov, R., et al. A demonstration project of Global Alliance against Chronic Respiratory Diseases: prediction of interactions between air pollution and allergen exposure-the Mobile Airways Sentinel NetworK-Impact of air POLLution on Asthma and Rhinitis approach. Chin Med J (Engl) 133 (2020), 1561–1567.
Sousa-Pinto, B., Palamarchuk, Y., Leeman, L., Jankin, S., Basagana, X., Ballester, J., et al. From MASK-air® and SILAM to CATALYSE (Climate Action To Advance HeaLthY Societies in Europe). J Invest Allergol Clin Immunol 34 (2024), 12–19.
Bousquet, J., Bedbrook, A., Czarlewski, W., Onorato, G.L., Arnavielhe, S., Laune, D., et al. Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma. Clin Transl Allergy, 9, 2019, 16.
OECD. Integrating care to prevent and manage chronic diseases: best practices in public health. 2023, OCDE, Paris.
Sousa-Pinto, B., Azevedo, L.F., Jutel, M., Agache, I., Canonica, G.W., Czarlewski, W., et al. Development and validation of combined symptom-medication scores for allergic rhinitis. Allergy 77 (2022), 2147–2162.
Sousa-Pinto, B., Jacome, C., Perreira, A., Regateiro, F., Almeida, R., Czarlewski, W., et al. Development and validation of an electronic daily control score for asthma (e-DASTHMA). Lancet Digital Health 5 (2023), e227–e238.
Bousquet, J., Shamji, M.H., Anto, J.M., Schunemann, H.J., Canonica, G.W., Jutel, M., et al. Patient-centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA-EAACI approach. Allergy 78 (2023), 1758–1776.
Pfaar, O., Sousa-Pinto, B., Papadopoulos, N.G., Larenas-Linnemann, D.E., Ordak, M., Torres, M.J., et al. Digitally-enabled, person-centred care (PCC) in allergen immunotherapy: an ARIA-EAACI position paper. Allergy 79 (2024), 2037–2050.
Bousquet, J., Samolinski, B., Kaidashev, I., Maurer, M., Roche, N., Sousa-Pinto, B., et al. UCRAID (Ukrainian Citizen and refugee electronic support in Respiratory diseases, Allergy, Immunology and Dermatology) action plan. Allergy 78 (2023), 2581–2595.
Bousquet, J., Anto, J.M., Sousa-Pinto, B., Czarlewski, W., Bedbrook, A., Haahtela, T., et al. Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: the ARIA-MASK-air® approach. Clin Transl Allergy, 13, 2023, e12215.