Article (Scientific journals)
Cost-Effectiveness Analysis of Photobiomodulation After Third Molar Extraction for Pain Control.
Campos, Thalita Molinos; Campos, Mayra Costanti Vilela; Mesquita-Ferari, Raquel Agnelli et al.
2025In International Journal of Environmental Research and Public Health, 22 (2), p. 159
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Keywords :
cost-effectiveness; low-level laser; oral surgery; orofacial pain; photobiomodulation; Humans; Pain, Postoperative; Pain Management/methods; Pain Management/economics; Brazil; Cost-Effectiveness Analysis; Cost-Benefit Analysis; Molar, Third/surgery; Low-Level Light Therapy/methods; Low-Level Light Therapy/economics; Tooth Extraction; Low-Level Light Therapy; Molar, Third; Pain Management; Pollution; Public Health, Environmental and Occupational Health; Health, Toxicology and Mutagenesis
Abstract :
[en] [en] UNLABELLED: This study aims to evaluate the cost-effectiveness of photobiomodulation applied after third molar extraction. MATERIALS AND METHODS: To evaluate cost-effectiveness, 15 studies were selected for a systematic review and 8 studies for a meta-analysis to determine the effectiveness of photobiomodulation after surgery. In the present study, as a measure of effectiveness, the pain scale (visual analog scale) was used. The laser value was extracted from the Unified Terminology of Supplementary Health (Brazilian Health System) according to the laser application protocol most common among the clinical trials selected for the meta-analysis. As for drugs, they were determined from those most used among the works included in the meta-analysis and within the protocols established by the Brazilian Ministry of Health. RESULTS: The results of the overall analysis show a significant reduction in pain on the second day after surgery for the experimental group compared to the control (MD, -1.15; 95% CI, -1.73, -0.57). The control group has a lower cost and lower effectiveness, while laser treatment has a higher cost and higher effectiveness. Faced with this situation, the professional must clinically assess whether the cost of USD 34.62 for controlled pain intensity using the laser is worth the extra health benefit. CONCLUSIONS: Regarding the cost-effectiveness assessment, the control group has a lower cost and lower effectiveness, while laser treatment has a higher cost and higher effectiveness The decision of which treatment to choose must consider whether the cost of the therapeutic alternative outweighs the clinical gain caused by the treatment. CLINICAL RELEVANCE: One of the most executed procedures in dentistry is the extraction of third molars. To reduce the negative post-surgical effects, anti-inflammatory drugs are prescribed, which can generate unwanted effects. Photobiomodulation is a technique to modulate inflammation, accelerate tissue repair, and reduce pain and discomfort in different clinical situations.
Disciplines :
Dentistry & oral medicine
Author, co-author :
Campos, Thalita Molinos;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Campos, Mayra Costanti Vilela;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Mesquita-Ferari, Raquel Agnelli;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil ; Postgraduate Program in Rehabilitation Sciences, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Horliana, Anna Carolina Ratto Tempestini;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Bussadori, Sandra Kalil;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil ; Postgraduate Program in Rehabilitation Sciences, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Duran, Cinthya Cosme Gutierrez ;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil ; Postgraduate Program in Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Padilha, Alexandre;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Brugnera Júnior, Aldo ;  Education College of the European Master in Oral Laser Applications (EMDOLA), University of Liege, Pl. du Vingt Août 7, 4000 Liège, Belgium ; IFSC, University of São Paulo, USP, Avenida Trabalhador São-Carlense, n° 400, Parque Arnold Schimidt-CEP, São Carlos 13566-590, SP, Brazil
Namour, Samir  ;  Université de Liège - ULiège > Département des sciences dentaires
Navarro, Ricardo Scarparo;  Bioengineering Postgraduate Program, Scientific and Technological Institute, Universidade Brasil, Rua Carolina Fonseca, 584, São Paulo 08230-030, SP, Brazil
Fernandes, Kristianne Porta Santos;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Motta, Lara Jansiski;  Postgraduate Program in Biophotonics Medicine, Nove de Julho University (UNINOVE), Rua Vergueiro, 235/249-Liberdade, São Paulo 01504-001, SP, Brazil
Language :
English
Title :
Cost-Effectiveness Analysis of Photobiomodulation After Third Molar Extraction for Pain Control.
Publication date :
25 January 2025
Journal title :
International Journal of Environmental Research and Public Health
ISSN :
1660-4601
eISSN :
1661-7827
Publisher :
MDPI, Switzerland
Volume :
22
Issue :
2
Pages :
159
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
CAPES - Coordenação de Aperfeicoamento de Pessoal de Nível Superior
Funding text :
This study was financed in part by the Coordena\u00E7\u00E3o de Aperfei\u00E7oamento de Pessoal de N\u00EDvel Superior\u2013Brasil (CAPES)\u2013Finance Code 001.
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