A difficult path to point-of-care measurement of glomerular filtration rate.

[en] Transdermal detection of fluorescent markers has potential to provide point-of-care measurement of glomerular filtration rate. However, validation of proposed approaches and confirmation of their clinical utility should be required ahead of their adoption in the clinic.

Disciplines :

Urology & nephrology

Author, co-author :

Delanaye, Pierre ; Université de Liège - ULiège > Département des sciences cliniques > Néphrologie

Glassock, Richard J; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

Language :

English

Title :

A difficult path to point-of-care measurement of glomerular filtration rate.

Publication date :

12 March 2025

Journal title :

Nature Reviews Nephrology

ISSN :

1759-5061

eISSN :

1759-507X

Publisher :

Springer Science and Business Media LLC, England

Volume :

Pages :

285-286

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://www.nature.com/articles/s41581-025-00947-0.pdf

Available on ORBi :

since 23 April 2025

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Bibliography

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National Kidney Foundation K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification Am. J. Kidney Dis. 39 Suppl. 1 S1 S266
P. Delanaye C. Mariat The applicability of eGFR equations to different populations Nat. Rev. Nephrol. 9 513 522 1:CAS:528:DC%2BC3sXhsVWrurjK 10.1038/nrneph.2013.143 23856996
N. Ebert et al. Assessment of kidney function: clinical indications for measured GFR Clin. Kidney J. 14 1861 1870 1:CAS:528:DC%2BB3MXis1Sgs77M 10.1093/ckj/sfab042 34345408 8323140
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N. Ebert et al. Iohexol plasma clearance measurement protocol standardization for adults: a consensus paper of the European Kidney Function Consortium Kidney Int. 106 583 596 1:CAS:528:DC%2BB2cXhvVWrsr7M 10.1016/j.kint.2024.06.029 39097002
R.B. Dorshow M.P. Debreczeny S.L. Goldstein J.J. Shieh Clinical validation of the novel fluorescent glomerular filtration rate tracer agent relmapirazin (MB-102) Kidney Int. 106 679 687 1:CAS:528:DC%2BB2cXhs1OjsbzK 10.1016/j.kint.2024.06.012 38964736
R.B. Dorshow M.P. Debreczeny S.L. Goldstein Glomerular filtration rate measurement utilizing transdermal detection methodology J. Am. Soc. Nephrol. 10.1681/ASN.0000000639 39918882