Zebrafish; Toxicology; ZET; Phenotypes; Morphology; Mode of Action; Chemicals
Abstract :
[en] The zebrafish embryotoxicity test (ZET) has become increasingly prominent in evaluating the bioactivity and safety of chemicals and drugs, attracting scientists and legislators. Within the joint projects between the Laboratory for Organogenesis and Regeneration (ULiege) and the Faculty of Biology (VNU University of Science, Vietnam), we found that some chemicals may induce specific morphological effects on zebrafish embryos. Some of these phenotypic endpoints may indicate underlying mechanisms involved. Our studies have added several specific endpoints to the collection of bioactive indicators.
Disciplines :
Veterinary medicine & animal health Life sciences: Multidisciplinary, general & others
Author, co-author :
Dinh Duy Thanh ; Université de Liège - ULiège > Faculté des Sciences > Doct. scienc. (bioch. biol. moléc. cell. bioinf. mod. ; Université de Liège - ULiège > GIGA
Muller, Marc ; Université de Liège - ULiège > GIGA > GIGA Cancer - Molecular Angiogenesis Laboratory ; Université de Liège - ULiège > GIGA > GIGA I3 - Laboratory for Organogenesis and Regeneration
Tran, My Hanh ; Université de Liège - ULiège > Département des sciences de la vie ; Université de Liège - ULiège > GIGA > GIGA I3 - Laboratory for Organogenesis and Regeneration
Lai-Thanh, Nguyen; VNU University of Science > Cell Biology
Language :
English
Title :
Zebrafish Embryonic Phenotypes as Indicators for Chemical’s Modes of Action
Publication date :
29 November 2024
Event name :
L’Université de Liège et le Vietnam : des partenariats durables
Event organizer :
ULiège
Event place :
Liège, Belgium
Event date :
29 November 2024
Audience :
International
Tags :
GIGA Animal Facility
Development Goals :
3. Good health and well-being 14. Life below water
