[en] "Placenta Accreta Spectrum" (PAS) is a rare but serious pregnancy condition where the placenta abnormally adheres to the uterine wall and fails to spontaneously release after delivery. When it occurs, PAS is associated with high maternal morbidity and mortality - as PAS management can be particularly challenging. This two-part review summarizes current evidence in PAS management, identifies its most challenging aspects, and offers evidence-based recommendations to improve management strategies and PAS outcomes. The first part of this two-part review highlighted the general anesthetic approach, surgical and interventional management strategies, specialized "centers of excellence," and multidisciplinary PAS treatment teams. The high rates of PAS morbidity and mortality are often provoked by PAS-associated coagulopathies and peripartal hemorrhage (PPH). Anesthesiologists need to be prepared for massive blood loss, transfusion, and to manage potential coagulopathies. In this second part of this two-part review, we specifically reviewed the current literature pertaining to hemostatic changes, blood loss, transfusion management, and postpartum venous thromboembolism prophylaxis in PAS patients. Taken together, the two parts of this review provide a comprehensive survey of challenging aspects in PAS management for anesthesiologists.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Enste, Rick ; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Cricchio, Patrick; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Dewandre, Pierre-Yves ; Université de Liège - ULiège > Département des sciences cliniques
Braun, Thorsten ; Department of Obstetrics and 'Exp. Obstetrics', Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Leonards, Christopher O; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Niggemann, Phil ; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Spies, Claudia ; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Henrich, Wolfgang; Department of Obstetrics and 'Exp. Obstetrics', Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Kaufner, Lutz ; Department of Anesthesiology and Operative Intensive Care Medicine (CCM, CVK), Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Language :
English
Title :
Placenta Accreta Spectrum Part II: hemostatic considerations based on an extended review of the literature.
Competing interests: All authors state no conflict of interest in relation to this study. R.E. states no conflict of interest. P.C. states no conflict of interest. PY.D. received honoraria for lecture and consulting for CAF-DCF an LFB company. T.B. received research funds in relation to DFG-project BR2925/11-1. C.O.L. states no conflict of interest. P.N. states no conflict of interest. C.S. reports grants from Deutsche Forschungsgemeinschaft/German Research Society, grants from Deutsches Zentrum für Luft- und Raumfahrt e.V. (DLR)/German Aerospace Center, grants from Einstein Stiftung Berlin/Einstein Foundation Berlin, grants from Gemeinsamer Bundesausschuss/Federal Joint Committee (G-BA), grants from Inneruniversitäre Forsch-ungsförderung/Inner University Grants, grants from Projektträger im DLR/Porject Management Agency, grants from Stifterverband/Non-Profit Society Promoting Science and Education, grants from European Society of Anaesthesiology and Intensive Care, grants from Baxter Deutschland GmbH, grants from Fresenius Medical Care, grants from Grünenthal GmbH, grants from Masimo Europe Ltd., grants from Pfizer Pharma PFE GmbH, personal fees from Georg Thieme Verlang, grants from Dr. F. Köhler Chemie GmbH, grants from Sintetica GmbH, grants from Stifterverband für die deutsche Wissenschaft e.V./Philips, grants from Stiftung Charité, grants from AGUETTANT Deutschland GmbH, grants from AbbVie Deutschland GmbH & Co. KG, grants from Amomed Pharma GmbH, grants from InTouch Health, grants from Copra System GmbH, grants from Correvio GmbH, grants from Gemeinsamer Bundesausschuss/Federal Joint Committee (G-BA) -Innovationsfond, grants from Max-Planck-Gesellschaft zur Förderung der Wissenschaft e.V., grants from Deutsche Gesellschaft für Anesthesiologie & Intensivmedizin (DGAI), grants from Stifterverband für die deutsche Wissenschaft e.V./Medtronic, grants from Philips Electronics Nederland BV, grants from BMBF/RKI, grants from BMBF, grants from Deutsche Forschungsgemeinschaft/German Research Societ, grants from Drägerwerk AG & Co. KGaA outside the submitted work. In addition C.S. has the patents 10 2014 215 211.9, 10 2018 114 364.8, 10 2018 110 275.5, 50 2015 010 534.8, 50 2015 010 347.7, 10 2014 215 212.7 licensed. W.H. states no conflict of interest. L.K. reports honoraria for lecture from Novo Nordisk, CSL Behring and HICC Deutschland GbR.
Collins, SL, Alemdar, B, van Beekhuizen, HJ, Bertholdt, C, Braun, T, Calda, P, et al.. Evidence-based guidelines for the management of abnormally invasive placenta: recommendations from the International Society for Abnormally Invasive Placenta. Am J Obstet Gynecol 2019;220:511-26. https://doi.org/10.1016/j.ajog.2019.02.054.
Jauniaux, E, Chantraine, F, Silver, RM, Langhoff-Roos, J. For the FIGO placenta accreta diagnosis and management expert consensus panel. FIGO consensus guidelines on placenta accreta spectrum disorders: epidemiology. Int J Gynecol Obstet 2018;140:265-73. https://doi.org/10.1002/ijgo.12407.
Esakoff, TF, Sparks, TN, Kaimal, AJ, Kim, LH, Feldstein, VA, Goldstein, RB, et al.. Diagnosis and morbidity of placenta accreta: diagnosis and morbidity of placenta accreta. Ultrasound Obstet Gynecol 2011;37:324-7. https://doi.org/10.1002/uog.8827.
Quist-Nelson, J, Crank, A, Oliver, EA, Kim, CH, Richard, S, George, B, et al.. The compliance with a patient-safety bundle for management of placenta accreta spectrum. J Matern Fetal Neonatal Med 2019;34:1-7. https://doi.org/10.1080/14767058.2019.1671349.
Nieto, AJ, Echavarría, MP, Carvajal, JA, Messa, A, Burgos, JM, Ordoñez, C, et al.. Placenta accreta: importance of a multidisciplinary approach in the Colombian hospital setting. J Matern Fetal Neonatal Med 2020;33:1321-9. https://doi.org/10.1080/14767058.2018.1517328.
Khokhar, RS, Baaj, J, Khan, MU, Dammas, FA, Rashid, N. Placenta accreta and anesthesia: a multidisciplinary approach. Saudi J Anaesth 2016;10:332-4. https://doi.org/10.4103/1658-354x.174913.
Sivasankar, C. Perioperative management of undiagnosed placenta percreta: case report and management strategies. Int J Womens Health 2012;4:451-4. https://doi.org/10.2147/ijwh.s35104.
Fratto, VM, Conturie, CL, Ballas, J, Pettit, KE, Stephenson, ML, Truong, YN, et al.. Assessing the multidisciplinary team approaches to placenta accreta spectrum across five institutions within the University of California fetal Consortium (UCfC). J Matern Fetal Neonatal Med 2021;34:2971-6. https://doi.org/10.1080/14767058.2019.1676411.
Nieto-Calvache, AJ, López-Girón, MC, Quintero-Santacruz, M, Bryon, AM, Burgos-Luna, JM, Echavarría-David, MP, et al.. A systematic multidisciplinary initiative may reduce the need for blood products in patients with abnormally invasive placenta. J Matern Fetal Neonatal Med 2022;35:738-44. https://doi.org/10.1080/14767058.2020.1731460.
Biele, C, Kaufner, L, Schwickert, A, Nonnenmacher, A, von Weizsäcker, K, Muallem, MZ, et al.. Conservative management of abnormally invasive placenta complicated by local hyperfibrinolysis and beginning disseminated intravascular coagulation. Arch Gynecol Obstet 2021;303:61-8. https://doi.org/10.1007/s00404-020-05721-0.
Matsuzaki, S, Yoshino, K, Endo, M, Tomimatsu, T, Takiuchi, T, Mimura, K, et al.. Successful anticoagulant therapy for disseminated intravascular coagulation during conservative management of placenta percreta: a case report and literature review. BMC Pregnancy Childbirth 2017;17:443. https://doi.org/10.1186/s12884-017-1634-8.
Salim, R, Chulski, A, Romano, S, Garmi, G, Rudin, M, Shalev, E. Precesarean prophylactic balloon catheters for suspected placenta accreta: a randomized controlled trial. Obstet Gynecol 2015;126:1022-8. https://doi.org/10.1097/aog.0000000000001113.
Zhu, H, Wang, S, Shi, J, Yao, L, Wang, L, Chen, H, et al.. Prophylactic endovascular balloon occlusion of the aorta in cases of placenta accreta spectrum during caesarean section: points from the anaesthesiologist's perspective. BMC Pregnancy Childbirth 2020;20:446. https://doi.org/10.1186/s12884-020-03136-y.
Dai, M, Jin, G, Lin, J, Zhang, Y, Chen, Y, Zhou, Q, et al.. Control of postpartum hemorrhage in women with placenta accreta spectrum using prophylactic balloon occlusion combined with Pituitrin intra-arterial infusion. Eur Radiol 2020;30:4524-33. https://doi.org/10.1007/s00330-020-06813-w.
Cali, G, Forlani, F, Giambanco, L, Amico, ML, Vallone, M, Puccio, G, et al.. Prophylactic use of intravascular balloon catheters in women with placenta accreta, increta and percreta. Eur J Obstet Gynecol Reprod Biol 2014;179:36-41. https://doi.org/10.1016/j.ejogrb.2014.05.007.
Sentilhes, L, Ambroselli, C, Kayem, G, Provansal, M, Fernandez, H, Perrotin, F, et al.. Maternal outcome after conservative treatment of placenta accreta. Obstet Gynecol 2010;115:526-34. https://doi.org/10.1097/aog.0b013e3181d066d4.
Schwickert, A, van Beekhuizen, HJ, Bertholdt, C, Fox, KA, Kayem, G, Morel, O, et al.. Association of peripartum management and high maternal blood loss at cesarean delivery for placenta accreta spectrum (PAS): a multinational database study. Acta Obstet Gynecol Scand 2021;100(1 Suppl):29-40. https://doi.org/10.1111/aogs.14103.
Frank Wolf, M, Maymon, S, Shnaider, O, Singer-Jordan, J, Maymon, R, Bornstein, J, et al.. Two approaches for placenta accreta spectrum: B-lynch suture versus pelvic artery endovascular balloon. J Matern Fetal Neonatal Med 2020;33:2711-7. https://doi.org/10.1080/14767058.2018.1558199.
Fishel Bartal, M, Papanna, R, Zacharias, NM, Soriano-Calderon, N, Limas, M, Blackwell, SC, et al.. Planned versus unplanned delivery for placenta accreta spectrum. Am J Perinatol 2020;39:252-8. https://doi.org/10.1055/s-0040-1714676.
Schröder, L, Pötzsch, B, Rühl, H, Gembruch, U, Merz, WM. Tranexamic acid for hyperfibrinolytic hemorrhage during conservative management of placenta percreta. Obstet Gynecol 2015;126:1012-5.
Weiniger, CF, Elram, T, Ginosar, Y, Mankuta, D, Weissman, C, Ezra, Y. Anaesthetic management of placenta accreta: use of a pre-operative high and low suspicion classification. Anaesthesia 2005;60:1079-84. https://doi.org/10.1111/j.1365-2044.2005.04369.x.
Taylor, NJ, Russell, R. Anaesthesia for abnormally invasive placenta: a single-institution case series. Int J Obstet Anesth 2017;30:10-5. https://doi.org/10.1016/j.ijoa.2017.01.008.
Bourrellier, L, Bensalem, R, Bersot, Y, Bertrand, A, Duminil, L, Malinovsky, JM, et al.. Disseminated intravascular coagulation syndrome two months after conservative management of placenta accreta. About two patients. Eur J Obstet Gynecol Reprod Biol 2017;215:266-7. https://doi.org/10.1016/j.ejogrb.2017.06.031.
Shamshirsaz, AA, Fox, KA, Erfani, H, Clark, SL, Hui, SK, Shamshirsaz, AA, et al.. Coagulopathy in surgical management of placenta accreta spectrum. Eur J Obstet Gynecol Reprod Biol 2019;237:126-30. https://doi.org/10.1016/j.ejogrb.2019.04.026.
Papillon-Smith, J, Hobson, S, Allen, L, Kingdom, J, Windrim, R, Murji, A. Prophylactic internal iliac artery ligation versus balloon occlusion for placenta accreta spectrum disorders: a retrospective cohort study. Int J Gynaecol Obstet 2020;151:91-6. https://doi.org/10.1002/ijgo.13256.
Saito, K, Mariya, T, Fujibe, Y, Saito, M, Hirokawa, N, Ishioka, S, et al.. Common iliac artery dissection as a complication of common iliac artery balloon occlusion for placenta percreta: a case report. J Obstet Gynaecol Res 2021;47:1172-7. https://doi.org/10.1111/jog.14601.
Zhou, X, Sun, X, Wang, M, Huang, L, Xiong, W. The effectiveness of prophylactic internal iliac artery balloon occlusion in the treatment of patients with pernicious placenta previa coexisting with placenta accreta. J Matern Fetal Neonatal Med 2021;34:93-8. https://doi.org/10.1080/14767058.2019.1599350.
Yamada, T, Hirahata, E, Ihara, N, Nishimura, D, Inoue, K, Kato, J, et al.. Cesarean hysterectomy in a hybrid operating room for placenta percreta: a report of three cases. JA Clin Rep 2019;5:9. https://doi.org/10.1186/s40981-019-0230-5.
Mei, Y, Luo, D, Wei, S, Wang, L, Liao, X, Jing, H, et al.. Comparison of emergency cesarean hysterectomy with and without prophylactic placement of intravascular balloon catheters in patients with placenta accreta spectrum. J Matern Fetal Neonatal Med 2020;35:3190-5. https://doi.org/10.1080/14767058.2020.1815187.
Pinas-Carrillo, A, Bhide, A, Moore, J, Hartopp, R, Belli, AM, Arulkumaran, S, et al.. Outcomes of the first 50 patients with abnormally invasive placenta managed using the "Triple P Procedure" conservative surgical approach. Int J Gynaecol Obstet 2020;148:65-71. https://doi.org/10.1002/ijgo.12990.
Li, P, Liu, X, Li, X, Wei, X, Liao, J. Clinical outcomes and anesthetic management of pregnancies with placenta previa and suspicion for placenta accreta undergoing intraoperative abdominal aortic balloon occlusion during cesarean section. BMC Anesthesiol 2020;20:133. https://doi.org/10.1186/s12871-020-01040-8.
Peng, W, Shen, L, Wang, S, Wang, H. Retrospective analysis of 586 cases of placenta previa and accreta. J Obstet Gynaecol 2020;40:609-13. https://doi.org/10.1080/01443615.2019.1634019.
Liu, J, Xu, J, Jiao, D, Duan, X, Han, X. Comparison of the efficacy of prophylactic balloon occlusion of the abdominal aorta at or below the level of the renal artery in women with placenta accreta undergoing cesarean section. J Matern Fetal Neonatal Med 2021;34:2427-34. https://doi.org/10.1080/14767058.2019.1667325.
Whittington, JR, Pagan, ME, Nevil, BD, Kalkwarf, KJ, Sharawi, NE, Hughes, DS, et al.. Risk of vascular complications in prophylactic compared to emergent resuscitative endovascular balloon occlusion of the aorta (REBOA) in the management of placenta accreta spectrum. J Matern Fetal Neonatal Med 2022;35:3049-52. https://doi.org/10.1080/14767058.2020.1802717.
Stubbs, MK, Wellbeloved, MA, Vally, JC. The management of patients with placenta percreta: a case series comparing the use of resuscitative endovascular balloon occlusion of the aorta with aortic cross clamp. Indian J Anaesth 2020;64:520-3. https://doi.org/10.4103/ija.ija_121_20.
Tokue, H, Tokue, A, Tsushima, Y, Kameda, T. Safety and efficacy of aortic vs. internal iliac balloon occlusion for cesarean delivery in coexisting placenta accreta and placenta previa. Cardiovasc Intervent Radiol 2020;43:1277-84. https://doi.org/10.1007/s00270-020-02548-9.
Cho, SB, Hong, SJ, Lee, S, Won, JH, Choi, HC, Ha, JY, et al.. Preoperative prophylactic balloon-assisted occlusion of the internal iliac arteries in the management of placenta increta/percreta. Medicina 2020;56:368. https://doi.org/10.3390/medicina56080368.
Yuan, Q, Jin, Y, Chen, L, Ling, L, Bai, XM. Prophylactic uterine artery embolization during cesarean delivery for placenta previa complicated by placenta accreta. Int J Gynaecol Obstet 2020;149:43-7. https://doi.org/10.1002/ijgo.13072.
Titapant, V, Tongdee, T, Pooliam, J, Wataganara, T. Retrospective analysis of 113 consecutive cases of placenta accreta spectrum from a single tertiary care center. J Matern Fetal Neonatal Med 2020;33:3324-31. https://doi.org/10.1080/14767058.2018.1530757.
Kim, MJ, Kim, IJ, Kim, S, Park, IY. Postpartum hemorrhage with uterine artery embolization: the risk of complications of uterine artery embolization. Minim Invasive Ther Allied Technol 2022;31:276-83. https://doi.org/10.1080/13645706.2020.1789662.
Frasca, D. A Cesarean hysterectomy for invading placenta percreta: anesthetic safety considerations - a case report. AANA J 2012;80:373-8.
Kamani, AA, Gambling, DR, Christilaw, J, Flanagan, ML. Anaesthetic management of patients with placenta accreta. Can J Anaesth 1987;34:613-7. https://doi.org/10.1007/bf03010522.
Desbriere, R, Pascal, A, Katsogiannou, M, Mace, P, Laplane, C, Amar-Millet, A, et al.. Delayed disseminated intravascular coagulation revealed by spontaneous hematomas after conservative treatment of placenta percreta. Eur J Obstet Gynecol Reprod Biol 2018;226:77-8. https://doi.org/10.1016/j.ejogrb.2018.05.020.
Kume, K, Tsutsumi, MY, Soga, T, Sakai, Y, Kambe, N, Kawanishi, R, et al.. A case of placenta percreta with massive hemorrhage during cesarean section. J Med Invest 2014;61:208-12. https://doi.org/10.2152/jmi.61.208.
Binici, O, Büyükflrat, E. Anesthesia for cesarean section in parturients with abnormal placentation: a retrospective study. Cureus 2019;11:e5033. https://doi.org/10.7759/cureus.5033.
Karacaer, F, Biricik, E, Ilglnel, M, Tunay, D, Sucu, M, Ünlügenç, H. Retrospective analysis of eighty-nine caesarean section cases with abnormal placental invasion. Turk J Anaesthesiol Reanim 2019;47:112-9. https://doi.org/10.5152/tjar.2018.31799.
Atallah, D, Abou Zeid, H, Moubarak, M, Moussa, M, Nassif, N, Jebara, V. "You only live twice": multidisciplinary management of catastrophic case in placenta Accreta Spectrum-a case report. BMC Pregnancy Childbirth 2020;20:135. https://doi.org/10.1186/s12884-020-2817-2.
Ma, Y, You, Y, Jiang, X, Lin, X. Use of nitroglycerin for parallel transverse uterine cesarean section in patients with pernicious placenta previa and placenta accrete and predicted difficult airway: a case report and review of literature. Med 2020;99:e18943. https://doi.org/10.1097/md.0000000000018943.
Ito, M, Oshita, K, Tanaka, K, Hara, M, Hiraki, T. Massive obstetric hemorrhage during cesarean section in a patient after conception by frozen-thawed embryo transfer: a case report. JA Clin Rep 2020;6:2. https://doi.org/10.1186/s40981-019-0308-0.
Cojocaru, L, Lankford, A, Galey, J, Bharadwaj, S, Kodali, BS, Kennedy, K, et al.. Surgical advances in the management of placenta accreta spectrum: establishing new expectations for operative blood loss. J Matern Fetal Neonatal Med 2020;3:1-10. https://doi.org/10.1080/14767058.2020.1852213.
Urfalloglu, A, Öksüz, G, Bilal, B, Teksen, S, Callşlr, F, Boran, ÖF, et al.. Retrospective evaluation of anesthetic management in cesarean sections of pregnant women with placental anomaly. Anesthesiol Res Pract 2020;2020:1358258. https://doi.org/10.1155/2020/1358258.
Bartels, HC, Mulligan, KM, Craven, S, Rogers, AC, Higgins, S, O'Brien, DJ, et al.. Maternal morbidity in placenta accreta spectrum following introduction of a multi-disciplinary service compared to standard care: an Irish perspective. Ir J Med Sci 2021;190:1451-7. https://doi.org/10.1007/s11845-020-02473-3.
Khoiwal, K, Gaurav, A, Kapur, D, Kumari, O, Sharma, P, Bhandari, R, et al.. Placenta percreta-a management dilemma: an institutional experience and review of the literature. J Turk Ger Gynecol Assoc 2020;21:228-35. https://doi.org/10.4274/jtgga.galenos.2020.2020.0106.
Imtiaz, R, Masood, Z, Husain, S, Husain, S, Izhar, R, Hussain, S. A comparison of antenatally and intraoperatively diagnosed cases of placenta accreta spectrum. J Turk Ger Gynecol Assoc 2020;21:84-9. https://doi.org/10.4274/jtgga.galenos.2019.2019.0063.
Herbert, K, Buchbinder, L, Seshachellam, V, Lee, L. Resuscitative endovascular balloon occlusion of the aorta and concomitant tranexamic acid for cesarean hysterectomy complicated by common femoral artery thrombosis: a case report. Cureus 2020;12:e11197. https://doi.org/10.7759/cureus.11197.
Bluth, A, Schindelhauer, A, Nitzsche, K, Wimberger, P, Birdir, C. Placenta accreta spectrum disorders-experience of management in a German tertiary perinatal centre. Arch Gynecol Obstet 2021;303:1451-60. https://doi.org/10.1007/s00404-020-05875-x.
Chen, M, Liu, X, You, Y, Wang, X, Li, T, Luo, H, et al.. Internal iliac artery balloon occlusion for placenta previa and suspected placenta accreta: a randomized controlled trial. Obstet Gynecol 2020;135:1112-9. https://doi.org/10.1097/aog.0000000000003792.
Bergakker, SA. Case report: management of elective cesarean delivery in the presence of placenta previa and placenta accreta. AANA J 2010;78:380-4.
Erez, O. Disseminated intravascular coagulation in pregnancy-clinical phenotypes and diagnostic scores. Thromb Res 2017;151(1 Suppl):56-60. https://doi.org/10.1016/S0049-3848(17)30069-5.
Erez, O, Mastrolia, SA, Thachil, J. Disseminated intravascular coagulation in pregnancy: insights in pathophysiology, diagnosis and management. Am J Obstet Gynecol 2015;213:452-63. https://doi.org/10.1016/j.ajog.2015.03.054.
Schwickert, A, Chantraine, F, Ehrlich, L, Henrich, W, Muallem, MZ, Nonnenmacher, A, et al.. Maternal serum VEGF predicts abnormally invasive placenta better than NT-proBNP: a multicenter case-control study. Reprod Sci 2021;28:361-70. https://doi.org/10.1007/s43032-020-00319-y.
Snir, A, Brenner, B, Paz, B, Ohel, G, Lanir, N. The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading. Thromb Res 2013;132:477-83. https://doi.org/10.1016/j.thromres.2013.08.023.
Solomon, C, Collis, RE, Collins, PW. Haemostatic monitoring during postpartum haemorrhage and implications for management. Br J Anaesth 2012;109:851-63. https://doi.org/10.1093/bja/aes361.
Guo, Z, Han, X, Zhang, H, Zheng, W, Yang, H, Ma, J. Association between pre-delivery coagulation indicators and invasive placenta accreta spectrum. Clin Appl Thromb Hemost 2022;28:107602962110705. https://doi.org/10.1177/10760296211070580.
Chen, Y, Wang, L, Bao, J, Sha, X, Cui, L, Huang, Q, et al.. Persistent hypoxia induced autophagy leading to invasiveness of trophoblasts in placenta accreta. J Matern Fetal Neonatal Med 2021;34:1297-303. https://doi.org/10.1080/14767058.2019.1635582.
Jauniaux, E, Hussein, AM, Elbarmelgy, RM, Elbarmelgy, RA, Burton, GJ. Failure of placental detachment in accreta placentation is associated with excessive fibrinoid deposition at the utero-placental interface. Am J Obstet Gynecol 2022;226:243.e1-10. https://doi.org/10.1016/j.ajog.2021.08.026.
Judy, AE, Lyell, DJ, Druzin, ML, Dorigo, O. Disseminated intravascular coagulation complicating the conservative management of placenta percreta. Obstet Gynecol 2015;126:1016-8. https://doi.org/10.1097/aog.0000000000000960.
Al-Khan, A, Bulmer, JN, Chantraine, F, Chen, CP, Chen, Q, Collins, S, et al.. IFPA Meeting 2012 Workshop Report III: trophoblast deportation, gestational trophoblastic disease, placental insufficiency and fetal growth restriction, trophoblast over-invasion and accreta-related pathologies, placental thrombosis and fibrinolysis. Placenta 2013;34:S11-6. https://doi.org/10.1016/j.placenta.2012.11.018.
Muñoz, M, Acheson, AG, Auerbach, M, Besser, M, Habler, O, Kehlet, H, et al.. International consensus statement on the peri-operative management of anaemia and iron deficiency. Anaesthesia 2017;72:233-47. https://doi.org/10.1111/anae.13773.
Mueller, MM, Van Remoortel, H, Meybohm, P, Aranko, K, Aubron, C, Burger, R, et al.. Patient blood management: recommendations from the 2018 frankfurt consensus conference. JAMA 2019;321:983-97. https://doi.org/10.1001/jama.2019.0554.
Kaufner, L, von Heymann, C. AWMF Leitlinie 001-024l_S3_Praeoperative-Anaemie; 2018. [Online]. Available from: https://www.awmf.org/uploads/tx_szleitlinien/001-024l_S3_Praeoperative-Anaemie_2018-04-verlaengert.pdf.
Zdanowicz, JA, Surbek, D. Patient blood management in obstetrics-Review. Transfus Apher Sci 2019;58:412-5. https://doi.org/10.1016/j.transci.2019.06.017.
Surbek, D, Vial, Y, Girard, T, Breymann, C, Bencaiova, GA, Baud, D, et al.. Patient blood management (PBM) in pregnancy and childbirth: literature review and expert opinion. Arch Gynecol Obstet 2020;301:627-41. https://doi.org/10.1007/s00404-019-05374-8.
Butwick, AJ, McDonnell, N. Antepartum and postpartum anemia: a narrative review. Int J Obstet Anesth 2021;47:102985. https://doi.org/10.1016/j.ijoa.2021.102985.
Mauritz, AA, Dominguez, JE, Guinn, NR, Gilner, J, Habib, AS. Blood-conservation strategies in a blood-refusal parturient with placenta previa and placenta percreta. A A Case Rep 2016;6:111-3. https://doi.org/10.1213/xaa.0000000000000258.
Harding, K, Holmes, A, Phillips, C, Lightfood, D, Osman, I, Black, M, et al.. Antenatal care for uncomplicated pregnancies, NICE Guidance, 2021 [Online]. Available from: https://www.nice.org.uk/guidance/ng201.
Breymann, C, Honegger, C, Hösli, I, Surbek, D. Diagnosis and treatment of iron-deficiency anaemia in pregnancy and postpartum. Arch Gynecol Obstet 2017;296:1229-34. https://doi.org/10.1007/s00404-017-4526-2.
Pavord, S, Myers, B, Robinson, S, Allard, S, Strong, J, Oppenheimer, C, et al.. UK guidelines on the management of iron deficiency in pregnancy. Br J Haematol 2012;156:588-600. https://doi.org/10.1111/j.1365-2141.2011.09012.x.
Hobson, SR, Kingdom, JC, Murji, A, Windrim, RC, Carvalho, JCA, Singh, SS, et al.. No. 383-Screening, diagnosis, and management of placenta accreta spectrum disorders. J Obstet Gynaecol Can 2019;41:1035-49. https://doi.org/10.1016/j.jogc.2018.12.004.
Kaufner, L, Henkelmann, A, von Heymann, C, Feldheiser, A, Mickley, L, Niepraschk-von Dollen, K, et al.. Can prepartum thromboelastometry-derived parameters and fibrinogen levels really predict postpartum hemorrhage? J Perinat Med 2017;45:427-35. https://doi.org/10.1515/jpm-2016-0009.
Karlsson, O, Jeppsson, A, Thornemo, M, Lafrenz, H, Rådström, M, Hellgren, M. Fibrinogen plasma concentration before delivery is not associated with postpartum haemorrhage: a prospective observational study. Br J Anaesth 2015;115:99-104. https://doi.org/10.1093/bja/aev039.
Collins, PW, Lilley, G, Bruynseels, D, Laurent, DBS, Cannings-John, R, Precious, E, et al.. Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study. Blood 2014;124:1727-36. https://doi.org/10.1182/blood-2014-04-567891.
de Lange, NM, van Rheenen-Flach, LE, Lancé, MD, Mooyman, L, Woiski, M, van Pampus, EC, et al.. Peri-partum reference ranges for ROTEM(R) thromboelastometry. Br J Anaesth 2014;112:852-9. https://doi.org/10.1093/bja/aet480.
Charbit, B, Mandelbrot, L, Samain, E, Baron, G, Haddaoui, B, Keita, H, et al.. The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage. J Thromb Haemostasis 2007;5:266-73. https://doi.org/10.1111/j.1538-7836.2007.02297.x.
Bonhomme, F, Boehlen, F, Clergue, F, de Moerloose, P. Preoperative hemostatic assessment: a new and simple bleeding questionnaire. Can J Anesth/J Can Anesth 2016;63:1007-15. https://doi.org/10.1007/s12630-016-0688-9.
Kahr, MK, Brun, R, Zimmermann, R, Franke, D, Haslinger, C. Validation of a quantitative system for real-time measurement of postpartum blood loss. Arch Gynecol Obstet 2018;298:1071-7. https://doi.org/10.1007/s00404-018-4896-0.
Diaz, V, Abalos, E, Carroli, G. Methods for blood loss estimation after vaginal birth. Cochrane Database Syst Rev 2018;9:CD010980. https://doi.org/10.1002/14651858.CD010980.pub2.
Bamberg, C, Niepraschk-von Dollen, K, Mickley, L, Henkelmann, A, Hinkson, L, Kaufner, L, et al.. Evaluation of measured postpartum blood loss after vaginal delivery using a collector bag in relation to postpartum hemorrhage management strategies: a prospective observational study. J Perinat Med 2015;44:433-9. https://doi.org/10.1515/jpm-2015-0200.
Brecher, M, Monk, T, Goodnough, L. A standardized method for calculating blood loss. Transfusion 1997;37:1070-4. https://doi.org/10.1046/j.1537-2995.1997.371098016448.x.
Eckerdal, P, Kollia, N, Löfblad, J, Hellgren, C, Karlsson, L, Högberg, U, et al.. Delineating the association between heavy postpartum haemorrhage and postpartum depression. Plos One 2016;11:e0144274. https://doi.org/10.1371/journal.pone.0144274.
Muñoz, M, Stensballe, J, Ducloy-Bouthors, AS, Bonnet, MP, De Robertis, E, Fornet, I, et al.. Patient blood management in obstetrics: prevention and treatment of postpartum haemorrhage. In: A NATA consensus statement. Milan, Italy: Blood Transfusion; 2019, vol. 17:112-36 pp.
Prick, B, Jansen, A, Steegers, E, Hop, W, Essink-Bot, M, Uyl-de Groot, C, et al.. Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial. BJOG An Int J Obstet Gynaecol 2014;121:1005-14. https://doi.org/10.1111/1471-0528.12531.
American College of Obstetricians and Gynecologists. ACOG practice bulletin: clinical management guidelines for obstetrician-gynecologists number 76, October 2006: postpartum hemorrhage. Obstet Gynecol 2006;108:1039-47. https://doi.org/10.1097/00006250-200610000-00046.
Patil, V, Ratnayake, G, Fastovets, G, Wijayatilake, DS. Clinical pearls part 3: anaesthetic management of abnormally invasive placentation. Curr Opin Anaesthesiol 2018;31:280-9. https://doi.org/10.1097/aco.0000000000000601.
Practice Bulletin No 183. Postpartum hemorrhage. Obstet Gynecol 2017;130:e168-86. https://doi.org/10.1097/AOG.0000000000002346.
Gattas, DJ, Dan, A, Myburgh, J, Billot, L, Lo, S, Finfer, S, et al.. CHEST Management Committee. Fluid resuscitation with 6% hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: systematic review of effects on mortality and treatment with renal replacement therapy. Intensive Care Med 2013;39:558-68. https://doi.org/10.1007/s00134-013-2840-0.
Hunsicker, O, Francis, RC. Assessment of hemodynamic efficacy and safety of 6% hydroxyethyl starch 130/0.4 vs. 0.9% NaCl fluid replacement in patients with severe sepsis: how to guide fluid therapy? Crit Care 2012;16:464. https://doi.org/10.1186/cc11836.
Eur. Med. Agency. Hydroxyethyl-starch solutions (HES) should no longer be used in patients with sepsis or burn injuries critically ill-CMDh endorses PRAC recommendations; 2013 [Online]. Available from: https://www.ema.europa.eu/en/news/hydroxyethyl-starch-solutions-hes-should-no-longer-be-used-patients-sepsis-burn-injuries-critically.
Mardel, SN, Saunders, FM, Allen, H, Menezes, G, Edwards, CM, Ollerenshaw, L, et al.. Reduced quality of clot formation with gelatin-based plasma substitutes. Br J Anaesth 1998;80:204-7. https://doi.org/10.1093/bja/80.2.204.
Kozek-Langenecker, SA, Ahmed, AB, Afshari, A, Albaladejo, P, Aldecoa, C, Barauskas, G, et al.. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology First update 2016. Eur J Anaesthesiol 2017;34:332-95. https://doi.org/10.1097/eja.0000000000000630.
Khan, KS, Moore, P, Wilson, M, Hooper, R, Allard, S, Wrench, I, et al.. A randomised controlled trial and economic evaluation of intraoperative cell salvage during caesarean section in women at risk of haemorrhage: the SALVO (cell SALVage in Obstetrics) trial. Health Technol Assess 2018;22:1-88. https://doi.org/10.3310/hta22020.
Waters, JH, Beck, S, Yazer, MH. How do I perform cell salvage in obstetrics? Transfusion 2019;59:2199-202. https://doi.org/10.1111/trf.15352.
Rogers, WK, Wernimont, SA, Kumar, GC, Bennett, E, Chestnut, DH. Acute hypotension associated with intraoperative cell salvage using a leukocyte depletion filter during management of obstetric hemorrhage due to amniotic fluid embolism. Anesth Analg 2013;117:449-52. https://doi.org/10.1213/ane.0b013e3182938079.
Ralph, C, Faulds, J, Sullivan, I. Cell salvage and leucocyte depletion filters. Anaesthesia 2010;65:1228-9. https://doi.org/10.1111/j.1365-2044.2010.06547.x.
Simonazzi, G, Bisulli, M, Saccone, G, Moro, E, Marshall, A, Berghella, V. Tranexamic acid for preventing postpartum blood loss after cesarean delivery: a systematic review and meta-analysis of randomized controlled trials. Acta Obstet Gynecol Scand 2016;95:28-37. https://doi.org/10.1111/aogs.12798.
Sentilhes, L, Sénat, MV, Le Lous, M, Winer, N, Rozenberg, P, Kayem, G, et al.. Tranexamic acid for the prevention of blood loss after cesarean delivery. N Engl J Med 2021;384:1623-34. https://doi.org/10.1056/nejmoa2028788.
WOMAN Trial Collaborators. Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial. Lancet 2017;389:2105-16. https://doi.org/10.1016/S0140-6736(17)30638-4.
Schlembach, D, Helmer, H, Henrich, W, von Heymann, C, Kainer, F, Korte, W, et al.. Peripartum haemorrhage, diagnosis and therapy. Guideline of the DGGG, OEGGG and SGGG (S2k level, AWMF registry No. 015/063, march 2016). Geburtshilfe Frauenheilkd 2018;78:382-99. https://doi.org/10.1055/a-0582-0122.
World Health Organization. WHO recommendation on tranexamic acid for the treatment of postpartum haemorrhage; 2017. [Online]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK493081/.
Mavrides, E, Allard, S, Chandraharan, E, Collins, P, Green, L, Hunt, BJ, et al.. Prevention and management of postpartum haemorrhage: green-top guideline no. 52. BJOG 2017;124:e106-49. https://doi.org/10.1111/1471-0528.14178.
Butwick, A, Lyell, D, Goodnough, L. How do I manage severe postpartum hemorrhage? Transfusion 2020;60:897-907. https://doi.org/10.1111/trf.15794.
Bates, SM, Rajasekhar, A, Middeldorp, S, McLintock, C, Rodger, MA, James, AH, et al.. American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy. Blood Adv 2018;2:3317-59. https://doi.org/10.1182/bloodadvances.2018024802.
Samama, CM, Albaladejo, P, Laversin, S, Marret, E. Prévention de la maladie thromboembolique veineuse périopératoire et obstétricale. Ann Fr Anesth Reanim 2005;24:853-61. https://doi.org/10.1016/j.annfar.2005.06.011.
Nelson-Piercy, C, MacCallum, P, Mackillop, L. Reducing the risk of venous thromboembolism during pregnancy and the puerperium green-top guideline no. 37a April 2015. London, UK: Royal College of Obstetricians & Gynaecologists; 2015.
Encke, A, Haas, S, Kopp, I, Abholz, HH, Bode, C, Bootz, F, et al.. S3-Leitlinie prophylaxe der venösen Thromboembolie (VTE), 2. Komplett überarbeitete Auflage 2015;238:95-9.
Sang, CQ, Zhao, N, Zhang, J, Wang, SZ, Guo, SL, Li, SH, et al.. Different combination strategies for prophylaxis of venous thromboembolism in patients: a prospective multicenter randomized controlled study. Sci Rep 2018;8:8277. https://doi.org/10.1038/s41598-018-25274-2.
Feng, JP, Xiong, YT, Fan, ZQ, Yan, LJ, Wang, JY, Gu, ZJ. Efficacy of intermittent pneumatic compression for venous thromboembolism prophylaxis in patients undergoing gynecologic surgery: a systematic review and meta-analysis. Oncotarget 2017;8:20371-9. https://doi.org/10.18632/oncotarget.13620.
Kakkos, SK, Caprini, JA, Geroulakos, G, Nicolaides, AN, Stansby, G, Reddy, DJ. Combined intermittent pneumatic leg compression and pharmacological prophylaxis for prevention of venous thromboembolism in high-risk patients. In: Cochrane database of systematic reviews. Chichester, UK: John Wiley & Sons; 2008. [Online].
Sabri, S, Roberts, VC, Cotton, LT. Prevention of early postoperative deep vein thrombosis by intermittent compression of the leg during surgery. BMJ 1971;4:394-6. https://doi.org/10.1136/bmj.4.5784.394.
