Allergic reactions; Cow milk protein allergies; Cows' milk; Earliest life; Food allergies; Milk protein
Abstract :
[en] Cow's milk protein allergy (CMPA) is considered as the most common food allergy in early life and may cause anaphylaxis reactions in severe cases. This review summarises recent findings in CMPA studies, especially regarding the main relevant cow's milk substitutes such as hydrolysed and plant-based (soy and rice) formulas in addition to other mammalian milk types (goat, sheep, donkey, mare and camel) to reduce allergy risks for children. Extensively hydrolysed cow's milk formulas are mainly used as an alternative for children with CMPA, despite their poor palatability. Goat's and sheep's milk and soy-based formulas are not recommended because of their high cross-reactivity with cow's milk proteins. On the contrary, equine's and camel's milk proteins are suggested as suitable alternative solutions due to their low sequence identity levels with cow's milk proteins. Nonetheless, further research needs to confirm the usefulness of these milk types as a solution in paediatric CMPA.
Disciplines :
Food science
Author, co-author :
Lajnaf, Roua ; Alimentary Analysis Unit, National Engineering School of Sfax, Sfax, Tunisia ; Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia ; Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia
Feki, Sawsan; Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia
Ben Ameur, Salma; Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia
Attia, Hamadi; Alimentary Analysis Unit, National Engineering School of Sfax, Sfax, Tunisia
Kammoun, Thouraya; Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia
Ayadi, Mohamed ; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Masmoudi, Hatem; Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia
Language :
English
Title :
Cow's milk alternatives for children with cow's milk protein allergy - Review of health benefits and risks of allergic reaction
This work is carried out under the MOBIDOC scheme, funded by The Ministry of Higher Education and Scientific Research of the Tunisian government through the PromESsE project and managed by the ANPR. This research was partially supported by the L'Oréal UNESCO for Women in Science Maghreb Fellowships 2022.
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