[en] Cow's milk proteins allergy (CMA) is an atypical immune system response to cow's milk and dairy products. It's one of the most common food allergies in children affecting 8% of the total pediatric population pediatric population. This comprehensive review examines recent studies in CMA, especially regarding mammalian milk allergies such as goat's, sheep's, buffalo's, camel's, mare's and donkey's milk allergies in order to increase awareness of these selective allergies and to reduce allergy risks for those who have them. The consumption of other mammalian milk types is not recommended because of the significant homology between milk proteins from cow, sheep, goat and buffalo resulting in clinical cross-reactivity. However, camel's, mare's or donkey's milk may be tolerated by some allergic patients. Selective mammalian milk allergies are unusual and rare disorders characterized by severe symptoms including angio-oedema, urticaria, respiratory manifestations and anaphylaxis. Based on the reported allergic cases, cheese products including Ricotta, Romano, Pecorino and Mozzarella, are considered as the most common source of allergens especially in goat's, sheep's and buffalo's milk allergies, while the major allergens in donkey's and mare's milk seems to be whey proteins including lysozyme, α-lactalbumin and β-lactogloblin due to the low casein/whey proteins ratio in equine's milk.
Disciplines :
Food science
Author, co-author :
Lajnaf, Roua ; Alimentary Analysis Unit, National Engineering School of Sfax, BPW 3038, Sfax, Tunisia, Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia, Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia. Electronic address: roua_lajnaf@yahoo.fr
Feki, Sawsan; Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia
Ben Ameur, Salma; Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia
Attia, Hamadi; Alimentary Analysis Unit, National Engineering School of Sfax, BPW 3038, Sfax, Tunisia
Kammoun, Thouraya; Pediatric Department, Hédi Chaker University Hospital, Sfax, Tunisia
Ayadi, Mohamed ; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Masmoudi, Hatem; Immunology Department, Habib Bourguiba University Hospital, Sfax, Tunisia
Language :
English
Title :
Recent advances in selective allergies to mammalian milk proteins not associated with Cow's Milk Proteins Allergy.
This work is carried out under the MOBIDOC scheme, funded by The Ministry of Higher Education and Scientific Research of the Tunisian government through the PromESsE project and managed by the ANPR. This research was partially supported by the L'Oréal Unesco for Women in Science Maghreb Fellowships , 2021/2022.
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