Biomarkers in Atopic Dermatitis.

Atopic dermatitis (AD) is a chronic inflammatory skin condition. The pathogenesis involves genetic, environmental, and immunological factors as well as a barrier dysfunction of the epidermis. Biomarkers may play a significant role in diagnosis, severity assessment, and treatment monitoring of AD. They are categorizable into diagnostic and prognostic as well as severity and stratification biomarkers, offering the potential for a more personalized treatment approach. Although there have been tremendous therapeutic advancements with interleukin (IL) antagonists and Janus kinase (JAK) inhibitors, the domain of biomarkers still requires further research to clarify their place in the diagnosis and prognosis of AD to unravel a better scientific basis for personalized medical care for patients with AD. This article reviews the various biomarkers in relation to the different AD phenotypes and endotypes.

Disciplines :

Dermatology

Author, co-author :

Libon, Florence ; Centre Hospitalier Universitaire de Liège - CHU > > Service de dermatologie

Caron, Juliette; Allergology and Therapeutic Education Service, Saint Vincent-de-Paul Hospital, Lille Cedex, France

Nikkels, Arjen ; Université de Liège - ULiège > Département des sciences cliniques > Dermatologie

Language :

English

Title :

Biomarkers in Atopic Dermatitis.

Publication date :

July 2024

Journal title :

Dermatology and Therapy

ISSN :

2193-8210

eISSN :

2190-9172

Publisher :

Springer, Heidelberg, Germany

Volume :

Issue :

Pages :

1729 - 1738

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://link.springer.com/content/pdf/10.1007/s13555-024-01193-1.pdf

Available on ORBi :

since 29 October 2024

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