Establishment of a similarity evaluation model for human Milk phospholipids: A comparative study on the composition and structure of human Milk phospholipids and its natural resources
[en] Human milk phospholipids (HMPLs) play an indispensable role in the neurodevelopment and growth of infants. In this study, a total of 37 phospholipid fatty acid (PLFA) species and 139 phospholipid molecular species were detected from human milk and other natural phospholipid sources (including 5 animal-derived species and 2 plant species). Moreover, a similarity evaluation model for HMPLs was established, including phospholipid classes, PLFAs, and phospholipid molecular species, to evaluate their natural substitutes. The closest scores for HMPL substitute in these three dimensions was 0.89, 0.72, and 0.77, which belonged to mare milk, goat milk, and camel milk, respectively. The highest comprehensive similarity score was obtained by camel milk at 0.75, while the lowest score was observed in soybean phospholipid (0.22). Therefore, these results not only monitored the stereochemical structure of HMPLs and their substitutes, but also further provided new insights for the development of infant formulae.
Disciplines :
Agriculture & agronomy Chemistry
Author, co-author :
Zhu, Huiquan ; Université de Liège - ULiège > TERRA Research Centre
Fauconnier, Marie-Laure ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)
Zhang, Hong
Xu, Xuebing
Wang, Xiaodan
Zhang, Yumeng
Guo, Ruihua
Zhang, Wenyuan
Zhang, Shuwen
Wang, Yunna
Pang, Xiaoyang
Lv, Jiaping
Language :
English
Title :
Establishment of a similarity evaluation model for human Milk phospholipids: A comparative study on the composition and structure of human Milk phospholipids and its natural resources
NSCF - National Natural Science Foundation of China
Funding text :
This research was supported by the China Agriculture Research System
National Dairy Industry and Technology System (CARS 36), the National Key R&D Program of China (2021YFD2100700), the National Natural Science Foundation of China (Grant No.32302137), and Arawana Charity Foundation.
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