Establishment of a similarity evaluation model for human Milk phospholipids: A comparative study on the composition and structure of human Milk phospholipids and its natural resources

Zhu, Huiquan; Fauconnier, Marie-Laure; Zhang, Hong; Xu, Xuebing; Wang, Xiaodan; Zhang, Yumeng; Guo, Ruihua; Zhang, Wenyuan; Zhang, Shuwen; Wang, Yunna; Pang, Xiaoyang; Lv, Jiaping

doi:10.1016/j.foodchem.2024.140556

Article (Scientific journals)

Establishment of a similarity evaluation model for human Milk phospholipids: A comparative study on the composition and structure of human Milk phospholipids and its natural resources

Zhu, Huiquan; Fauconnier, Marie-Laure; Zhang, Hong et al.

2024 • In Food Chemistry, p. 140556

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/321447

DOI
10.1016/j.foodchem.2024.140556

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Keywords :

human milk; phospholipids

Abstract :

[en] Human milk phospholipids (HMPLs) play an indispensable role in the neurodevelopment and growth of infants. In this study, a total of 37 phospholipid fatty acid (PLFA) species and 139 phospholipid molecular species were detected from human milk and other natural phospholipid sources (including 5 animal-derived species and 2 plant species). Moreover, a similarity evaluation model for HMPLs was established, including phospholipid classes, PLFAs, and phospholipid molecular species, to evaluate their natural substitutes. The closest scores for HMPL substitute in these three dimensions was 0.89, 0.72, and 0.77, which belonged to mare milk, goat milk, and camel milk, respectively. The highest comprehensive similarity score was obtained by camel milk at 0.75, while the lowest score was observed in soybean phospholipid (0.22). Therefore, these results not only monitored the stereochemical structure of HMPLs and their substitutes, but also further provided new insights for the development of infant formulae.

Disciplines :

Agriculture & agronomy
Chemistry

Author, co-author :

Zhu, Huiquan ; Université de Liège - ULiège > TERRA Research Centre

Fauconnier, Marie-Laure ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)

Zhang, Hong

Xu, Xuebing

Wang, Xiaodan

Zhang, Yumeng

Guo, Ruihua

Zhang, Wenyuan

Zhang, Shuwen

Wang, Yunna

Pang, Xiaoyang

Lv, Jiaping

Language :

English

Title :

Establishment of a similarity evaluation model for human Milk phospholipids: A comparative study on the composition and structure of human Milk phospholipids and its natural resources

Publication date :

July 2024

Journal title :

Food Chemistry

ISSN :

0308-8146

eISSN :

1873-7072

Publisher :

Elsevier BV

Pages :

140556

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://api.elsevier.com/content/article/PII:S0308814624022064?httpAccept=text/xml

Funders :

NSCF - National Natural Science Foundation of China

Funding text :

This research was supported by the China Agriculture Research System National Dairy Industry and Technology System (CARS 36), the National Key R&D Program of China (2021YFD2100700), the National Natural Science Foundation of China (Grant No.32302137), and Arawana Charity Foundation.

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since 26 August 2024

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