Renal control of the peripheral uptake of exogenous gastrin in the dog

[en] The extraction of plasma gastrim during intravenous infusion of exogenous hormone has been measured in the head, gastrointestinal tract, or kidney of dogs sbmitted to sham srugery, evisceration, or binephrectomy without or with subsequent kidney transplantation. A significant gastrin extraction xas demontrated not only in the kidney, but also in the head and in the gastrointestinal tract; moreover, plasma gastrin extraction in the head and the bowel was considerably reduced by binephrectomy and was brought back to control values after subsequent kidney transplantation. A non specific effect of surgery and a variation in peripheral blood flow seem to be excluded. Thuis a control by the kidney the peripheral removal of blood gastrin is evidenced, the mechanism of wich remains hypthetical

Disciplines :

Hematology

Author, co-author :

Loly, Jean ; Université de Liège - ULiège > Département des sciences cliniques > Hépato-gastroentérologie

Depresseux, Jean-Claude ; Université de Liège - ULiège > Unités de recherche interfacultaires > GIGA-CRC In vivo Imaging (Centre de Recherche du Cyclotron)

Brassine, A.

Nizet, Adrien ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale

Language :

English

Title :

Renal control of the peripheral uptake of exogenous gastrin in the dog

Publication date :

1982

Journal title :

Pflügers Archiv: European Journal of Physiology

ISSN :

0031-6768

eISSN :

1432-2013

Publisher :

Springer, Berlin, Germany

Volume :

395

Pages :

171-174

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 14 May 2024

Statistics

Number of views

6 (0 by ULiège)

Number of downloads

4 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Becker H.D., Reeder D.D., Thompson J.C. (1973) Extraction of circulating endogenous gastrin by the small bowel. Gastroenterology 65(6):903-906.
Booth R.A.D., Reeder D.D., Hjelmquist U.B., Brandt E.N., Thompson J.C. (1973) Renal inactivation of endogenous gastrin in dogs. Arch Surg 106:851-854.
Buijs P.H.O. (1979) Gastrine. Ned Tijdschr Geneeskd 123(5):168-172.
Christensen C.K., Nielsen H.E., Katrup O., Olsen K.J., Brandsborg M., Brandsborg O. (1979) Serum gastrin and serum calcitonin in patients with chronic renal failure. Acta Endocrinol (Copenh) 91(3):564-570.
Clendinnen B.G., Reeder D.D., Brandt E.N., Thompson J.C. (1973) Effect of nephrectomy on the rate and pattern of disappearance of exogenous gastrin in dogs. Gut 14:462-467.
Davidson W.D., Springberg P.D., Falkinburg N.R. (1973) Renal extraction and excretion of endogenous gastrin in the dog. Gastroenterology 64:955-961.
Davidson W.D., Moore T.C., Shippey W., Conovaloff A.J. (1974) Effect of bilateral nephrectomy and bilateral ureteral ligation on serum gastrin levels in the rat. Gastroenterology 66:522-525.
Dencker H., Hakanson R., Liedberg G., Norryd C., Oscarson J., Rehfeld J.F., Stadil F. (1973) Gastrin in portal and peripheral venous blood after feeding in man. Gut 14:856-860.
El Munshid H.A., Liedberg G., Rehfeld J.F., Sundler F., Larsson L.I., Hakanson R. (1976) Effect of bilateral nephrectomy on serum gastrin concentration, gastric histamine content, histidine decarboxylase activity and acid secretion in the rat. Scand J Gastroenterol 11:87-91.
Evans J.C.W., Reeder D.D., Becker H.D., Thompson J.C. (1974) Extraction of circulating endogenous gastrin by the gastric fundus. Gut 15:112-115.
Gedde-Dahl D. (1975) Serum gastrin response to food stimulation in male azotemic patients. Scand J Gastroenterol 10:683-687.
Gedde-Dahl D., Flatmark A. (1975) Serum gastrin in patients with azotemia. Scand J Urol Nephrol 25-27.
Gold C.H., Morley J.E., Viljoen M., Outim L., De Foeca M., Kalk W.J. (1980) Gastric acid secretion and serum gastrin levels in patients with chronic renal failure on regular hemodialysis. Nephron 25:92-95.
Greco A.V., Altomonte L., Ghirlanda G., Rebuzzi A.G., Manna R., Bertoli A. (1979) Serum gastrin in portal and peripheral veins after arginine in man. Acta Hepatogastroenterol (Stuttg) 26(2):98-101.
Hallgren R., Landelius J., Fjellstrom K.E., Lundqvist G. (1979) Gastric acid secretion in uraemia and circulating levels of gastrin, somatostatin and pancreatic polypeptide. Gut 20:763-768.
Hansky J. (1979) Effect of renal failure on gastrointestinal hormones. World J Surg 31(3):463-467.
Hartung H., Kirchner R., Trendelenburg C. (1978) Metabolism of endogenous gastrin. Leber Magen Darm 8(2):87-90.
Hohnke L.A., Wilder D.E. (1978) Evidence for renal modulation of serum gastrin concentration in the rat. Scand J Gastroenterol 13:89.
Korman M.G., Laver M.C., Hansky J. (1972) Hypergastrinemia in chronic renal failure. Br Med J 1:209-210.
Korman M.G., Laver M.C., Hansky J. (1973) Azotemia and hypergastrinemia. Gastroenterology 64:132-133.
Lichardus B., Nizet A. (1972) Water and sodium excretion following blood volume expansion under conditions of constant arterial, venous and plasma oncotic pressures and constant haematocrit. Clin Sci 42:701-709.
Lundqvist H., Gustavsson S., Lundqvist G. (1978) Distribution and metabolism of gastrin. An experimental study of the fate of¹²³I gastrin in the rats as studied by external detection with a γ-camera. Eur Surg Res 10(2):109-120.
Lundqvist G., Hallgren R., Landelius J., Fjellstrom K.E. (1978) Further studies on plasma immunoreactive gastrin in uremia. Scand J Gastroenterol 13:117.
McGuigan J.E. (1977) Serum gastrin in health and disease. Am J Digest Dis 22:712-716.
Muolo A., Ghidini G., Ancona G., Franzin G., Galvani E., Rinaldi M., Confortini P. (1979) Gastroduodenal mucosal changes, gastric acid secretion, and gastrin levels, following successful kidney transplantation. Transplant Proc 11(2):1277-1278.
Nielsen H.E., Christensen C.K., Brandsborg M., Brandsborg O. (1980) The effect of renal transplantation on basal serum gastrin concentration. Acta Med Scand 207:85-87.
Rayford P.L., Thompson J.C. (1977) Gastrin. Surg Gynecol Obstet 145:257-268.
Reeder D.D., Brandt E.N., Watson L.C., Hjelmquist U.B., Thompson J.C. (1972) Pre- and post-hepatic measurements of man of endogenous gastrin. Surgery 72(1):34-41.
Shiu K.M. (1976) Hypergastrinemia in cirrhosis of liver. Gut 17:700-708.
Straus E., Gerson C.D., Yalow R.S. (1974) Hypersecretion of gastrin associated with the short bowel syndrome. Gastroenterology 66:175-180.
Strunz U.J., Walsh J.H., Grossman M.I. (1978) Removal of gastrin by various organs in dog. Gastroenterology 74:32.
Sveinsdottir E., Thorloff P., Risberg J., Infvar D.H., Lassen N.A. (1970) Calculation of regional cerebral blood flow: initial-slope-index compared to height-over-total-area values. Brain and blood flow , R.W., Ross Russel, Pitman, London; 85.
Taylor J.L., Dockray G.L. (1976) Hypergastrinemia in renal failure, the biological significance of molecular forms of gastrin. Br J Surg 63:657.
Thompson J.C., Reeder D.D., Davidson W.D., Charters A.C., Brückner W.L., Lemmi C.A.E., Miller J.H. (1969) Effect of hepatic transit of gastrin, pentagastrin and histamine measured by gastric secretion and by assay of hepatic vein blood. Ann Surg 170(3):493-503.
Thompson J.C., Rayford P.L., Ramus N.I., Fender H.R., Villar H.V. (1975) Patterns of release and uptake of heterogeneous forms of gastrin. Gastrointestinal hormones , J.C., Thompson, University of Texas Press, Austin Texas; 125-151.
Thompson J.C., Llanos O.L., Teichmann R.K., Schafmayer A., Rayford P.L. (1979) Catabolism of gastrin and secretin. World J Surg 31(3):469-475.
Wickbom G., Landor J.H., Bushkin F.L., McGuigan J.E. (1975) Changes in canine gastric acid output and serum gastrin levels following massive small intestinal resection. Gastroenterology 69:448-452.
Yamagata, Ishimori A., Sakurada H., Miura Y., Tsuda K., Kanamura T., Nakanome T., Yamagata S. (1976) Role of the kidney in gastrin metabolism. Tohoku J Exp Med 118:45-51.