Glomerular filtration rate estimation in adults: myths and promises.

[en] [en] BACKGROUND: In daily practice, glomerular filtration rate (GFR) is estimated with equations including renal biomarkers. Among these biomarkers, serum creatinine remains the most used. However, there are many limitations with serum creatinine we will discuss in the current review. We will also discuss how creatinine-based equations have been developed and what we can expect from them in terms of performance to estimate GFR. SUMMARY: Different creatinine-based equations have been proposed. We will show the advantages of the recent European Kidney Function Consortium (EKFC) equation. This equation can be used in children and adults. This equation can also be used with some flexibility in different populations. KEY MESSAGES: GFR is estimated by creatinine-based equations, but the most important for nephrologists is probably to know the limitations of these equations.

Disciplines :

Urology & nephrology
Laboratory medicine & medical technology

Author, co-author :

Delanaye, Pierre ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale

Cavalier, Etienne ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale

Stehlé, Thomas

Pottel, Hans ; Université de Liège - ULiège > Département des sciences cliniques

Language :

English

Title :

Glomerular filtration rate estimation in adults: myths and promises.

Publication date :

12 January 2024

Journal title :

Nephron journals

ISSN :

1660-8151

eISSN :

2235-3186

Publisher :

S. Karger AG, Switzerland

Pages :

1-7

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://karger.com/nef/article-pdf/doi/10.1159/000536243/4165105/000536243.pdf

Available on ORBi :

since 10 April 2024

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16 (2 by ULiège)

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