[en] Some non pathogenic microorganisms can induce disease resistance mechanisms expressed systemically in the host plant thereby rendering it less susceptible to further attack by pathogens. In this study, we have investigated the role of bacterial compounds as elicitors of the induced systemic resistance. Lipopeptides, especially surfactin and fengycin, produced by Bacillus subtilis strains are able to stimulate bean and tomato plants and decrease the impact of subsequent pathogen infection. Preliminary experiments on tobacco cells showed that surfactine induces some modifications in the phenylpropanoid pathway. Amphiphilic properties of lipopeptides and NABD, the elicitor isolated from Pseudomonas putida strain BTP1, could be responsible for their activities on plant cells