Analgesics; Injections; Obstetrics; Opioid; Regional anesthesia; Spinal; Critical Care and Intensive Care Medicine; Anesthesiology and Pain Medicine; General Medicine
Abstract :
[en] INTRODUCTION: Spinal anesthesia with intrathecal morphine (ITM) is a common anesthesia technique for cesarean delivery. The hypothesis was that the addition of ITM will delay micturition in women undergoing cesarean delivery.
METHODS: Fifty-six ASA physical status I and II women scheduled to undergo elective cesarean delivery under spinal anesthesia were randomized to the PSM group (50 mg prilocaine + 2.5 mcg sufentanil + 100 mcg morphine; n = 30) or PS group (50 mg prilocaine + 2.5 mcg sufentanil; n = 24). The patients in the PS group received a bilateral transverse abdominal plane (TAP) block. The primary outcome was the effect of ITM on the time to micturition and the secondary outcome was the need for bladder re-catheterization.
RESULTS: The time to first urge to urinate (8 [6-10] hours in the PSM group versus 6 [4-6] hours in the PS group) and the time to first micturition (10 [8-12] hours in the PSM group versus 6 [6-8] hours in the PS group) were significantly (p < 0.001) prolonged in the PSM group. Two patients in the PSM group met the 800 mL criterium for urinary catheterization after 6 and 8 h respectively.
CONCLUSION: This study is the first randomized trial to demonstrate that the addition of ITM to the standardized mixture of prilocaine and sufentanil significantly delayed micturition.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Gautier, Nicolas; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Lejeune, Delphine ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation ; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Al Zein, Lilas; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Kesteloot, Cédric; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Ciccarella, Yannick; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Bouvet, Lionel; Department of Anesthesia and Critical Care, Hospices Civils de Lyon, Lyon, France
Cops, Jirka ; NYSORA, New York, USA. Electronic address: jirka@nysora.com
Hadzic, Admir; Department of Anesthesiology, Ziekenhuis Oost-Limburg, Genk, Belgium, Department of Anesthesiology & Algology, Faculty of Medicine, KULeuven, Leuven, Belgium
Gautier, Philippe E; Department of Anesthesiology, Clinique Sainte-Anne Saint-Rémi - CHIREC, Anderlecht, Belgium
Language :
English
Title :
The effects of intrathecal morphine on urinary bladder function and recovery in patients having a cesarean delivery - A randomized clinical trial.
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