ANTOINE, M.-H., BERKENBOOM, G., FANG, Z. Y., FONTAINE, J., HERCHUELZ, A. AND LEBRUN, P.: Mechanical and ionic response of rat aorta to diazoxide. Eur. J. Pharmacol. 216: 299-306, 1992.
ANTOINE, M.-H., HERMANN, M., HERCHUELZ, A. AND LEBRUN, P.: Sodium nitroprusside inhibits glucose-induced insulin release by activating ATP-sensitive K+ channels. Biochim. Biophys. Acta 1175: 293-301, 1993.
ASHCROFT, F. M., HARRISON, D. E. AND ASHCROFT, S. J. H.: Glucose induces closure of single potassium channels in isolated rat pancreatic B-cells. Nature 312: 446-448, 1984.
ASHCROFT, F. M. AND RORSMAN, P.: Electrophysiology of the pancreatic B-cell. Prog. Biophys. Mol. Biol. 54: 87-143, 1989.
COOK, D. L. AND HALES, C. N.: Intracellular ATP directly blocks K+ channels in pancreatic B-cells. Nature 311: 271-273, 1984.
DUNNE, M. J.: Protein phosphorylation is required for diazoxide to open ATP-sensitive potassium channels in insulin (RINm5F) secreting cells. FEBS Lett. 250: 262-266, 1989.
DUNNE, M. J.: Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells. Br. J. Pharmacol. 99: 487-492, 1990.
DUNNE, M. J., FINDLAY, I. AND PETERSEN, O. H.: Effects of pyridine nucleotides on the gating of ATP-sensitive potassium channels in insulin-secreting cells. J. Membr. Biol. 12: 205-216, 1988.
GARRINO, M. G., PLANT, T. D. AND HENQUIN, J. C.: Effects of putative activators of K+ channels in mouse pancreatic B-cells. Br. J. Pharmacol. 98: 957-965, 1989.
HAMILL, O. P., MARTY, A., NEHER, E., SAKMANN, B. AND SIGWORTH, F. J.: Improved patch-clamp cell techniques for high resolution current recordings from cells and cell-free membrane patches. Pflugers Arch. 391: 85-100, 1981.
HARDING, E. A., JAGGAR, J. H., SQUIRES, P. E. AND DUNNE, M. J.: Polymyxin B has multiple blocking actions on the ATP-sensitive potassium channel in insulin-secreting cells. Pflügers Arch. 426: 31-39, 1994.
HELLMAN, B.: Calcium and pancreatic B-cell function. 3. Validity of the La3+-wash technique for discriminating between superficial and intracellular 46Ca. Biochim. Biophys. Acta 540: 534-542, 1978
HENQUIN, J. C., DEBUYSER, A., DREWS, G. AND PLANT, T. D.: Regulation of K+ permeability and membrane potential in insulin secreting cells. In Nutrient Regulation of Insulin Secretion, ed. by P. R. Flatt, pp. 173-191, Portland Press Ltd, London, 1992.
HERCHUELZ, A., COUTURIER, E. AND MALAISSE, W. J.: Regulation of calcium fluxes in pancreatic islets: glucose-induced calcium-calcium exchange. Am. J. Physiol. 238: E96-E103, 1980.
HERCHUELZ, A., POCHET, R., PASTIELS, C. AND VAN PRAET, A.: Heterogeneous changes in [Ca2+]1 induced by glucose, tolbutamide and K+ in single rat pancreatic B-cells. Cell Calcium 12: 577-586, 1991.
LEBRUN, P., ANTOINE, M.-H. AND HERCHUELZ, A.: Minireview: K+ channel openers and insulin release. Life Sci. 51: 795-806, 1992.
LEBRUN, P., DEVREUX, V., HESMANN, M. AND HERCHUELZ, A.: Pinacidil inhibits insulin release by increasing K+ outflow from pancreatic B-cells. Eur. J. Pharmacol. 156: 283-286, 1988.
LEBRUN, P., DEVREUX, V., HERMANN, M. AND HERCHUELZ, A.: Similarities between the effects of pinacidil and diazoxide on ionic and secretory events in rat pancreatic islets. J. Pharmacol. Exp. Ther. 250: 1011-1018, 1989.
LEBRUN, P. AND ATWATER, I.: Effects of the calcium channel agonist, BAY K 8644, on electrical activity in mouse pancreatic B-cells. Biophys. J. 48: 919-930, 1985.
LEBRUN, P., MALAISSE, W. J. AND HERCHUELZ, A.: Evidence for two distinct modalities of Ca2+ influx into pancreatic B-cell. Am. J. Physiol. 242: E59-E66, 1982.
LECLERCQ-MEYER, V., MARCHAND, J., REBOLLEDO, O., MALAISSE, W. J. AND LECLERCQ, R.: A combined radioimmunoassay for glucagon and insulin. Diabetologia 11: 419-425, 1975.
LEVY, J., HERCHUELZ, A., SENER, A., MALAISSE-LAGAE, F. AND MALAISSE, W. J.: Cytochalasin B-induced impairment of glucose metabolism in islets of Langerhans. Endocrinology 98: 429-437, 1976.
MALAISSE, W. J., BOSCHERO, A. C., KAWAZU, S., AND HUTTON, J. C.: The stimulus secretion coupling of glucose-induced insulin release. XXVII. Effect of glucose on K+ fluxes in isolated islets. Pflügers Arch. 373: 237-242, 1978.
MALAISSE, W. J. AND LEBRUN, P : Mechanisms of sulfonylurea-induced insulin release. Diabetes Care 13: suppl 3, 9-17, 1990.
PIROTTE, B., DE TULLIO, P., LEBRUN, P., ANTOINE, M.-H., FONTAINE, J., MASEREEL, B., SCHYNTS, M., DUPONT, L., HERCHUELZ, A. AND DELARGE, J.: 3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: A new class of potassium channel openers? J. Med. Chem. 36: 3211-3213, 1993.
PLASMAN, P.-O., HERCHUELZ, A. AND LEBRUN, P.: Dual effect of 1,4-dihydropyridines on Ca2+ inflow into rat pancreatic islet cells. Naunyn-Schmiedeberg's Arch. Pharmacol. 343: 90-95, 1991
RUDY, B.: Diversity and ubiquity of K channels. Neuroscience 25: 729-749, 1988.
STURGESS, N. C., ASHFORD, M. L. J., COOK, D. L. AND HALES, C. N.: The sulphonylurea receptor may be an ATP-sensitive potassium channel. Lancet 8453: 474-475, 1985.
TRUBE, G., RORSMAN, P. AND OHNO-SHOSAKU, T.: Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic B-cells. Pflügers Arch. 407: 493-499, 1986.
DE TULLIO P., PIROTTE B., LEBRUN P., FONTAINE J., DUPONT L., ANTOINE M.-H., OUEDRAOGO R., KHELILI S., MAGGETTO C., MASEREEL B., DIOUF O., PODONA T. AND DELARGE J.: 3- and 4-Substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers: Synthesis, pharmacological evaluation and structure-activity relationships. J. Med. Chem., in press, 1996.