Baile, C., McLaughlin, C. L., Della-Ferra, M. A. (1986) Role of cholecystokinin and opioid peptides in control of food intake. Physiol. Rev. 66: 172-234
Bell, S. C., Gochman, C., Wei, P. H. (1975) Synthesis of heterocyclic fused thiazolecarboxylic acids I. J. Heterocycl. Chem. 12: 1207-1210
Blundell, J. (1991) Pharmacological approaches to appetite suppression. Trends Pharmacol. Sci. 12: 147-157
Chang, R. S. L., Lotti, V. J. (1986) Biochemical and pharmacological characterization of a new extremely potent and selective non peptide cholecystokinin antagonist. Proc. Natl Acad. Sci. USA 83: 4923-4926
Chang, R. S. L., Lotti, V. J., Monaghan, R. L., Birnbaum, J., Stapley, E. O., Goötz, M. A., Albers-Schonberg, G., Patchett, A. A., Liesch, J. M., Hensens, O. D., Springer, J. P. (1985) A potent nonpeptide cholecystokinin antagonist selective for peripheral tissues isolated from Aspergillus alliaceus. Science 230: 177
Cherner, J. A., Sutliff, V. E., Grybowski, D. M., Jensen, R. T., Gardner, J. D. (1988) Functionally distinct receptors for cholecystokinin and gastrin on dispersed chief cells from guinea pig stomach. Am. J. Physiol. 254: G151-G155
Crawley, J. N., Corwin, R. L. (1994) Biological actions of cholecystokinin. Peptides 15: 731-755
de Tullio, P., Pirotte, B., Dupont, L., Masereel, B., Laeckmann, D., Podona, T., Diouf, O., Lebrun, P., Delarge, J. (1995) Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-thiadiazine 1,1-dioxides. Tetrahedron 51: 3221-3234
de Tullio, P., Pirotte, B., Lebrun, P., Fontaine, J., Dupont, L., Antoine, M.-H., Ouedraogo, R., Khelili, S., Maggetto, C., Masereel, B., Diouf, O., Podona, T., Delarge, J. (1996) 3- and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium-channel openers: synthesis, pharmacological evaluation and structure-activity relationships. J. Med. Chem. 39: 937-948
European Patent application (1988) no. 0 268 990 A2
Evans, B. E., Rittle, K. E., Bock, M. G., DiPardo, R. M., Freidinger, R. M., Whitter, W. L., Gould, N. P., Lundell, G. F., Hommick, C. F., Veber, D. F., Anderson, P. S., Chang, R. S. L., Lotti, V. J., Cerino, D. J., Chen, T. B., Kling, P. J., Kunkel, K. A., Springer, J. P., Hirshfield, J. (1987) Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists. J. Med. Chem. 30: 1229-1239
Freidinger, R. M. (1989) Cholecystokinin and gastrin antagonists. Med. Res. Rev. 9: 271-290
Goëtz, M. A., Lopez, M., Monaghan, R. L., Chang, R. S. L., Lotti, V. J., Chen, T. B. (1985) Asperlicin, a novel non-peptidal cholecystokinin antagonist from Aspergillus alliaceus, fermentation, isolation and biological properties. J. Antibiot. 41: 875-877
Hahne, W. F., Jensen, R. T., Lemp, G. F., Gardner, J. D. (1981) Proglumide and benzotript members of a different class of cholecystokinin receptor antagonists. Proc. Natl Acad. Sci. USA 78: 6304-6308
Hayao, S., Strycker, W., Phillips, B., Fujimori, H., Vidrio, H. (1968) Sedative, antiadrenergic, and hypotensive 2-substituted 2H-1,2,4-benzothiadiazin-3(4H)-one 1,1-dioxides. J. Med. Chem. 11: 1246-1248
Hersey, S. J., May, D., Schyberg, D. (1983) Stimulation of pepsinogen release from isolated gastric glands by cholecystokinin-like peptides. Am. J. Physiol. 244: 192-197
Iversen, L. L., Dourish, C. T., Iversen, S. D. (1991) Cholecystokinin receptors: synthetic antagonists with selectivity for receptor subtypes and possible clinical applications. Biochem. Soc. Trans. 19: 913-915
Jensen, R. T., Wank, S. A., Rowley, W. H., Sato, S., Gardner, J. D. (1989) Interaction of CCK with pancreatic acinar cells. Trends Pharmacol. Sci. 10: 418-423
Lejeune, R., Delarge, J., Thunus, L. (1984). Preparation de disulphure de mercapto-3-pyridinesulphonamide-2. J. Pharm. Belg. 39: 217-224
Liddle, R. A., Gertz, B. J., Kanayama, S., Beccaria, L., Coker, L. D., Turnbull, T. A. (1989) Effects of a novel cholecystokinin (CCK) receptor antagonist, MK-329, on gallbladder contraction and gastric emptying in humans. Implication for the physiology of CCK. J. Clin. Invest. 84: 1220-1225
Louie, D. S., Liang, J. P., Owyang, C. (1988) Characterization of a new CCK antagonist, L-364-718: in vitro and in vivo studies. Am. J. Physiol. 255: 261-266
Makovec, F., Chisté, R., Bani, M., Revel, L., Setnikar, I., Rovati, L. A. (1986) New glutamic and aspartic derivatives with potent CCK-antagonistic activity. Eur. J. Med. Chem. Chim. Ther. 21: 9-20
McRoberts, J. W. (1986) Cholecystokinin and pain: a review. Anesth. Prog. 33: 87-90
Moran, T. H., Robinson, P. H., Goldrich, M. S., McHugh, P. R. (1986) Two brain cholecystokinin receptors: implications for behavioural actions. Brain Res. 362: 175-179
Nadzan, A. M., Kerwin, J. F. (1991) Cholecystokinin agonists and antagonists. Ann. Rep. Med. Chem. 20: 191-200
Patel, S., Smith, A. J., Chapman, K. L., Fletcher, A. E., Kemp, J. A., Marshall, G. R., Hargreaves, R. J., Ryecroft, W., Iversen, L. L., Iversen, S. D., Baker, R., Showell, G. A., Bourrain, S., Eduvelil, J. G., Matassa, V. G., Freedman, S. B. (1994) Biological properties of the benzodiazepine amidine derivative L-740,093, a cholecystokinin-B/gastrin receptor antagonist with high affinity in vitro and high potency in vivo. Mol. Pharmacol. 46: 943-948
Petersen, H. J. (1973) Synthesis of 3-amino- and 3-substituted amino-2H-1,2,4-benzothiadiazine 1,1-dioxides. Acta Chem. Scand. 27: 2655-2660
Pirotte, B., Masereel, B., Schynts, M., Delarge, J. (1990) Les sulfamides diurétiques: des origines aux perspectives d'avenir. Chimie Nouvelle 8: 920-924
Pirotte, B., de Tullio, P., Lebrun, P., Antoine, M.-H., Fontaine, J., Masereel, B., Schynts, M., Dupont, L., Herchuelz, A., Delarge, J. (1993) 3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers? J. Med. Chem. 36: 3211-3213
Raffa, L., Di Bella, M., Melegari, M., Vampa, G. (1962) Ricerche nel campo della 1,2,4-benzotiadiazina. Il Farmaco 18: 331-339
Rehfeld, J. F., Larsson, L. I., Goltermann, N. R., Schwartz, T. W., Holst, J. J., Jensen, S. L., Morley, J. S. (1980) Neural regulation of pancreatic hormone secretion of C-terminal tetrapeptide of CCK. Nature 284: 33-38
Satoh, M., Kondoh, Y., Okamoto, Y., Nishida, A., Miyata, K., Ohta, M., Mase, T., Murase, K. (1995) New 1,4-benzodiazepin-2-one derivatives as gastrin/cholecystokinin-B antagonists. Chem. Pharm. Bull. 43: 2159-2167
Singh, L., Lewis, A. S., Field, M. J., Hughes, J., Woodruff, G. N. (1991) Evidence for an involvement of the brain cholecystokinin B receptor in anxiety. Proc. Natl. Acad. Sci. USA 88: 1130-1133
VanDijk, A., Richards, J. G., Trzeciak, A., Gillessen, D., Mohler, H. (1984) Cholecystokinin receptors: biochemical demonstration and autoradiographied localization in rat brain and pancreas using [3H]-cholecystokinin-8 as radioligand. J. Neurosci. 4: 1021-1033
Weller, H., Miller, A., Moquin, R., Dickinson, K., Hedberg, S., Moreland, S., Cohen, R., Delanay, C., Skwish, S., Williams, S. (1992) Benzothiadiazine dioxides: a new class of potent angiotensin-II (AT1) receptor antagonists. Bioorg. Med. Chem. Lett. 2: 115-112
West German Patent (1972) No. 2 155 483; Chem. Abstr. 77: 66325
Wettstein, J. G., Buèno, L., Junien, J. L. (1994) CCK antagonists: pharmacology and therapeutic interest. Pharmacol. Ther. 62: 267-282
Wollweber, H., Horstmann, H., Stoepel, K., Garthoff, B., Puls, W., Krause, H. P., Thomas, G. (1981) 3-Amino-2H-1,2,4-benzothiadiazine-1,1-dioxide mit antihypertensiver und potentieller diabetogener Wirkung. Arzneimittelforschung 31: 279-288
Woodruff, G. N., Hughes, J. (1991) Cholecystokinin antagonist. Ann. Rev. Pharmacol. Toxicol. 31: 469-501
Yu, D. H., Huang, S. C., Wank, S. A., Mantey, S., Gardner, J. D., Jensen, R. T. (1990) Pancreatic receptors for cholecystokinin: evidence for three receptor classes. Am. J. Physiol. 258: G86-G95
Yu, M. J., Thrasher, K. J., McCowan, J. R., Mason, N. R., Mendelsohn, L. G. (1991) Quinazolinone cholecystokinin-B receptor ligands. J. Med. Chem. 34: 1505-1508
Yu, M. J., McCowan, J. R., Mason, N. R., Deeter, J. B., Mendelsohn, L. G. (1992) Synthesis and X-ray crystallographic analysis of quinazolinone cholecystokinin: gastrin receptor ligands. J. Med. Chem. 35: 2534-2542